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Traip (NM_011634) Mouse Untagged Clone
CAT＃: MC200902
Traip (untagged) - Mouse TRAF-interacting protein (Traip), (10ug)
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | Trip |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC017374 sequence for NM_011634
CACGCGTCCGATTTGAAGGAACCGGAGCGGCGGCCGGTTCGGCCACCAAACTGTGTCTGTCGCTGGCAGC TGGTTCCCTGGGCTGCTTGAGTCGAGCCATCATGCCTATCCGCGCTCTGTGCACTATCTGCTCCGACTTC TTCGATCACTCCCGTGACGTGGCTGCCATCCACTGTGGCCACACTTTTCATCTGCAATGCCTAATCCAGT GGTTTGAGACAGCACCAAGTCGGACCTGCCCACAGTGTAGAATCCAGGTTGGCAAAAAGACTATTATAAA CAAACTTTTCTTTGACCTCGCCCAGGAAGAGGAGAATGTCTTGGATGCAGAATTCTTAAAGAATGAACTG GACAGCGTCAAAGCTCAGCTTTCCCAGAAAGACAGGGAGAAACGGGACAGCCAGGCCATTATCGACACTC TACGGGACACCCTGGAAGAACGCAATGCTACTGTGGAGTCCCTACAGAACGCCTTAAACAAGGCAGAGAT GCTGTGTTCCACCCTGAAAAAACAGATGAAGTTCCTGGAGCAGCGGCAGGATGAGACCAAACAAGCTCGG GAGGAGGCCCACCGACTCAAGTGCAAGATGAAAACCATGGAGCAAATTGAGCTCCTACTCCAGAGCCAGC GGTCTGAGGTGGAGGAGATGATTCGAGACATGGGTGTGGGACAGTCAGCGGTGGAGCAGCTGGCTGTGTA CTGCGTGTCCCTCAAGAAAGAGTATGAGAATCTGAAGGAAGCTCGGAAGGCCACAGGGGAACTGGCTGAC AGGTTGAAGAAGGATTTGGTGTCCTCTAGGAGTAAGTTGAAGACTCTCAACACTGAGCTGGATCAGGCCA AGTTAGAACTGAGGTCAGCCCAGAAGGACTTACAAAGTGCTGACCAGGAGATCATGAGCCTAAGAAAGAA GCTGATGATCCTCCAGGGAACCTTGAGCCTGCCTCCGGCGACCAATGAGACGGTCAGCCGCCTGGTTTTT GAGAGCCCAGCCCCTGTGGAGATGATGAACCCGAGGCTTCACCAGCCACCCTTCGGTGATGAGATTGATC TCAATACCACCTTTGATGTAAATACCCCTCCAACCCAGACCTCTGGCTCCCAGCATTGCCTCCCCAAGAA GCTGTGCCTGGAGAGGGCACGCTCTCCCATGCAGAATGTCCTCAAGAAGGTGCACAAAGTCTCCAAGCCG GAGTCCCAGCTCTCACTGGGTGGCCAGCGATGTGTAGGAGAGCTAGATGAGGAACTGGCTGGTGCCTTCC CTCTCTTCATCCGGAATGCTGTCCTGGGTCAGAAACAGCCCAACAGGACCACAGCAGAATCCCGTTGCAG CACAGATGTGGTAAGAATAGGCTTTGATGGGCTTGGAGGACGAACAAAATTCATCCAGCCTAGGGACACA ACCATTATCCGACCAGTGCCTGTTAAGTCCAAGGCCAAGAGTAAACAGAAAGTGAGAATAAAGACTGTGA GTTCTGCCTCCCAGCCCAAGCTGGATACCTTTTTATGTCAGTGAACGGTGACCAGAGTCATGTTTGCAAT TAGTGGGCCAAGACCTGGCTAACCGGAAGTGTTTTTGGAAGATGGCTCCTCTTGGACCAGTCCAAGAGAG ATGCCCAGAAAACACACTTCCTGTGTTCACTGCGCCCTGCACCACACTGGGAAGCCACATGACCAGTTTA CTGTTCCGATCAGCAGGGCCTACTTCCAGTTGCAGGGTTTTGCTTATAGCTACAACCAGGTGTGGCTGGA CTCCTTTTGTTTTTATAGAACAGGGTCACATTGACTCTAAGTGGATGGGAGTGCTGGAGGATCCTATGCA GGCTGTAGGACCCTGCGCTTGAACTCCTGCCTGCCTCCAGCTTATTGCTTGAAATTATGGGGTGAGGTGG TGATAGGGAAAGGTTGGGGAAGTTTTCTGTGTAAAATAAAAGGCATCTTTTCTTCTAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_011634 |
| Insert Size | 1413 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC017374, AAH17374 |
| RefSeq Size | 2024 bp |
| RefSeq ORF | 1413 bp |
| Locus ID | 22036 |
| UniProt ID | Q8VIG6 |
| Gene Summary | E3 ubiquitin ligase acting as a negative regulator of innate immune signaling. Inhibits activation of NF-kappa-B mediated by TNF. Negatively regulates TLR3/4- and RIG-I-mediated IRF3 activation and subsequent IFNB1 production and cellular antiviral response by promoting 'Lys-48'-linked polyubiquitination of TNK1 leading to its proteasomal degradation (By similarity) (PubMed:17544371, PubMed:22945920). Involved in response to genotoxic lesions during genome replication. Promotes H2AX and RPA2 phosphorylation after replication-associated DNA damage and assists fork progression at UV-induced replication-blocking lesions during S phase. Might also play a role in promoting translesion synthesis by mediating the assembly of 'Lys-63'-linked poly-ubiquitin chains on the Y-family polymerase POLN in order to facilitate bypass of DNA lesions and preserve genomic integrity. The function in translesion synthesis is controversial (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG207523 | Traip (tGFP-tagged) - Mouse TRAF-interacting protein (Traip) |
CNY 3,710.00 |
|
| MR207523 | Traip (Myc-DDK-tagged) - Mouse TRAF-interacting protein (Traip) |
CNY 3,656.00 |
|
| MR207523L3 | Lenti ORF clone of Traip (Myc-DDK-tagged) - Mouse TRAF-interacting protein (Traip) |
CNY 5,230.00 |
|
| MR207523L4 | Lenti ORF clone of Traip (mGFP-tagged) - Mouse TRAF-interacting protein (Traip) |
CNY 6,056.00 |
