RUNX2 (NM_001015051) Human 3' UTR Clone

Specifications

Product Data
Product Name	RUNX2 (NM_001015051) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AML3; CBF-alpha-1; CBFA1; CCD; CCD1; CLCD; OSF-2; OSF2; PEA2aA; PEBP2aA
ACCN	NM_001015051
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC221230 3’UTR clone of NM_001015051 The sequence shown below is from the reference sequence of NM_001015051. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATGGATGAATCTGTTTGGCGACCATATTGAAATTCCTCAGCAGTGGCCCAGTGGTATCTGGGGGCCACA TCCCACACGTATCAATATATACATATATAGAGAGAGTGCATATATATGTATATCGATTAGCTATCTACA AAGTGCCTATTTTTTAGAAGATTTTTCATTCACTCACTCAGTCATGATCTTGCAGCCATAAGAGGGTAG ATATTGAGAAGCAGAAGGCTCAAGAGAGACAATTGCAATCGAGCTTCAGATTGTTTACTATTTAAGATG TACTTTTACAAAGGAACAAAGAAGGGAAAAGGTATTTTTGTTTTTGTTGTTTGGTCTGTTATCATCAAT AACCTGTTCATATGCCAATTCAGAGAGGTGGACTCCAGGTTCAGGAGGGAGAAGAGCAAAGCCGCTTCC TCTCTGTGCTTTGAAACTTCACACCCTCACGGTGGCAGCTGTGTATGGACCAGTGCCCTCCGCAGACAG CTCACAAAACCAGTTGAGGTGCACTAAAGGGACATGAGGTAGAATGGATGCTTCCATCACAGTACCATC ATTCAGAATAACTCTTCCAATTTCTGCTTTCAGACATGCTGCAGGTCCTCATCTGAACTGTTGGGTTCG TTTTTTTTTTTTTTTTTCCTGCTCCAAGAAAGTGACTTCAAAAATAACTGATCAGGATAGATTATTTTA TTTTACTTTTTAACACTCCTTCTCCCCTTTTCCCACTGAACCAAAAAGAAATCCCATCCCTAAAACCTG CCTTCTCCTTTTATGCAAAACTGAAAATGGCAATACATTATTATAGCCATAATGGTATAGATAGTGATT GCGTTTGGCTATGTGTTGTTTTCTTTTTTTTTAAATTATGAATATGTGTAAAATCTGAGGTAACTTGCT AACGTGAATGGTCATATAACTTTAAAGATATATTTATAATTATTTAATGACATTTGGACCCTTGAAACA TTTCTTAGTGTATTGATATGTTGACTTCGGTCTCTAAAAGTGCTCTTTATTAAATAACAAATTTCTTCA GTGGTCTAGAGCCATATCTGAAATATTGCTAAGCAATTTCAGTTCATCCAGGCACAATGTGATTTTAAA AAATACTTCCATCTCCAAATATTTTAGATATAGATTGTTTTTGTGATGTATGAAGGAAATGTTATGTTT AGTTCTTTCAGATCTTTGAATGCCTCTAACACAGCTTTGCCTTCTAAAGCGGTAATTAGGGATTTAAAA AACAACCTTTAGCCCTTTATCAGCATGAAATGCTGGAGTGATGTGGTTTTCTAATTTCTTTGGGGTAAT TATGACTCTTGTCATATTAAAAAGACAAGCACAAGTAAATCATTGAACTACAGAAAAATGTTCTGTGGT TTCATAGTTAAGCAAAACTCTAAATCGCCAGGCTTCATAGCAAAGACATAGTCAGCTAAAAGCCGCACA TGTGGATAGAGGGTTCAATTATGAGACACCTAGTACAGGAGAGCAAAATTGCACCAGAGATTCTTAACC AACCAGCCTTACCAAACAACACAACAGGGGAACCCCAATCTGCCTTACCCAAGGCCCCACTGGCAGCTT TCCACAGAATTTGCATTTAGAGGAGCAGAATGACATCACTGTCCTTTGGGAGTAGGTCCTCTGAAAAGG CAGCAGGTTCCAGCAGGTAGCTGAGCTGAGAGGACATATGGCCCACGGGGACCTACAGACAGCCTTTGA CATTTGTATTTCTTACAATGGAGGGCCAAGGAGGGCAAGGGGCTGTGGAGTTTGGTGTCTACTAGTGTG TATGAATTTGAGCTAGAGTCCTTCTGTGGCATGCACTTTGACCACTCCTGGCAGTCACATGGCAGATTT CCAAGTGCAAATCCTTAATCCAAACAAGGATCATCTAATGACACCACCAGGCCAATCCCTGCTCTCCTC CCCGAAAAGTCAGGGTCCCTTCATTGGAATCCTCCACCCACCCAAGCAGAATTTAGCAGAGATTTGCC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001015051.4
Synonyms	AML3; CBF-alpha-1; CBFA1; CCD; CCD1; CLCD; OSF-2; OSF2; PEA2aA; PEBP2aA
Summary	This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2016]
Locus ID	860
MW	77.4

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