TGF beta 2 (TGFB2) (NM_003238) Human 3' UTR Clone

Specifications

Product Data
Product Name	TGF beta 2 (TGFB2) (NM_003238) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	G-TSF; LDS4; TGF-beta2
ACCN	NM_003238
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC220584 3’UTR clone of NM_003238 The sequence shown below is from the reference sequence of NM_003238. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATGATTGTAAAGTCTTGCAAATGCAGCTAAAATTCTTGGAAAAGTGGCAAGACCAAAATGACAATGATG ATGATAATGATGATGACGACGACAACGATGATGCTTGTAACAAGAAAACATAAGAGAGCCTTGGTTCAT CAGTGTTAAAAAATTTTTGAAAAGGCGGTACTAGTTCAGACACTTTGGAAGTTTGTGTTCTGTTTGTTA AAACTGGCATCTGACACAAAAAAAGTTGAAGGCCTTATTCTACATTTCACCTACTTTGTAAGTGAGAGA GACAAGAAGCAAATTTTTTTTAAAGAAAAAAATAAACACTGGAAGAATTTATTAGTGTTAATTATGTGA ACAACGACAACAACAACAACAACAACAAACAGGAAAATCCCATTAAGTGGAGTTGCTGTACGTACCGTT CCTATCCCGCGCCTCACTTGATTTTTCTGTATTGCTATGCAATAGGCACCCTTCCCATTCTTACTCTTA GAGTTAACAGTGAGTTATTTATTGTGTGTTACTATATAATGAACGTTTCATTGCCCTTGGAAAATAAAA CAGGTGTATAAAGTGGAGACCAAATACTTTGCCAGAAACTCATGGATGGCTTAAGGAACTTGAACTCAA ACGAGCCAGAAAAAAAGAGGTCATATTAATGGGATGAAAACCCAAGTGAGTTATTATATGACCGAGAAA GTCTGCATTAAGATAAAGACCCTGAAAACACATGTTATGTATCAGCTGCCTAAGGAAGCTTCTTGTAAG GTCCAAAAACTAAAAAGACTGTTAATAAAAGAAACTTTCAGTCAGAATAAGTCTGTAAGTTTTTTTTTT TCTTTTTAATTGTAAATGGTTCTTTGTCAGTTTAGTAAACCAGTGAAATGTTGAAATGTTTTGACATGT ACTGGTCAAACTTCAGACCTTAAAATATTGCTGTATAGCTATGCTATAGGTTTTTTCCTTTGTTTTGGT ATATGTAACCATACCTATATTATTAAAATAGATGGATATAGAAGCCAGCATAATTGAAAACACATCTGC AGATCTCTTTTGCAAACTATTAAATCAAAACATTAACTACTTTATGTGTAATGTGTAAATTTTTACCAT ATTTTTTATATTCTGTAATAATGTCAACTATGATTTAGATTGACTTAAATTTGGGCTCTTTTTAATGAT CACTCACAAATGTATGTTTCTTTTAGCTGGCCAGTACTTTTGAGTAAAGCCCCTATAGTTTGACTTGCA CTACAAATGCATTTTTTTTTTAATAACATTTGCCCTACTTGTGCTTTGTGTTTCTTTCATTATTATGAC ATAAGCTACCTGGGTCCACTTGTCTTTTCTTTTTTTTGTTTCACAGAAAAGATGGGTTCGAGTTCAGTG GTCTTCATCTTCCAAGCATCATTACTAACCAAGTCAGACGTTAACAAATTTTTATGTTAGGAAAAGGAG GAATGTTATAGATACATAGAAAATTGAAGTAAAATGTTTTCATTTTAGCAAGGATTTAGGGTTCTAACT AAAACTCAGAATCTTTATTGAGTTAAGAAAAGTTTCTCTACCTTGGTTTAATCAATATTTTTGTAAAAT CCTATTGTTATTACAAAGAGGACACTTCATAGGAAACATCTTTTTCTTTAGTCAGGTTTTTAATATTCA GGGGGAAATTGAAAGATATATATTTTAGTCGATTTTTCAAAAGGGGAAAAAAGTCCAGGTCAGCATAAG TCATTTTGTGTATTTCACTGAAGTTATAAGGTTTTTATAAATGTTCTTTGAAGGGGAAAAGGCACAAGC CAATTTTTCCTATGATCAAAAAATTCTTTCTTTCCTCTGAGTGAGAGTTATCTATATCTGAGGCTAAAG TTTACCTTGCTTTAATAAATAATTTGCCACATCATTGCAGAAGAGGTATCCTCATGCTGGGGTTAATAG AATATGTCAGTTTATCACTTGTCGCTTATTTAGCTTTAAAATAAAAATTAATAGGCAAAGCAATGGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003238.6
Synonyms	G-TSF; LDS4; TGF-beta2
Summary	This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Disruption of the TGF-beta/SMAD pathway has been implicated in a variety of human cancers. A chromosomal translocation that includes this gene is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. Mutations in this gene may be associated with Loeys-Dietz syndrome. This gene encodes multiple isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016]
Locus ID	7042
MW	77.9

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