TRIB1 (NM_025195) Human 3' UTR Clone

Specifications

Product Data
Product Name	TRIB1 (NM_025195) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	C8FW; GIG-2; GIG2; SKIP1; TRB-1; TRB1
ACCN	NM_025195
Insert Size	1962 bp
Sequence Data	Insert Sequence (showhide) >SC217203 3’UTR clone of NM_025195 The sequence shown below is from the reference sequence of NM_025195. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GACAGTGACATTAGTTCCTTCTTCTGCTAATCCCCAAAACCTCAGAAACCTCATAATTCTTAACACCTG GCATTTCCATTTCTAAAGATGGACAGGCCCTTTGGCGTGGTACCAACCAGATAATGACTGCATCAGGAT GAAAGCTGCTGAACTCGGCATGGCGCCTCCTCTTCTCTGTTGGGATGAGTGACTTTATTGATTTGAGCA GCATATGCTGTGATTGGCTGCCCTGCAAATTTGTTTCCCTTAAGGAACCCTCACCAACTATCTCTGCTG GATTTGGGAGTTCCGCATCTTTTGTGGAGGGCAGAGTATGGACATCTTACACCCGGTGGTCAAGTGTGT AATAAACTTGAGCATTCGAATGGGAGAAAAAGCAAATCGCACAATGACATATTTTGAGTAATAACCGTA TTTTTCACAGGGTGACAAATTGGGCCAATAAATCTGCCATCTTTGAACTCATCTTTGGTGGCTAGACTG CTACGGCAGCTTCTCTGATGGGAAAGTTCCTTTTTTGGCTTAACACTCACCCTTTCTTCACACTCACAT TTACCAATGACTCTGCTCCGTTTTTGGAGCAGACTGTTTTAAGTTGCTCAGGAGCCTGATGGAACCATG AACCGAGACTCTTCTCTGTTTCCTGCCAAGACCTCATCTGCACTAATGCCTTCTCCCTGACCTTGACAC TTCCCCCTTTAGCTATAAAAGCACTTACCAGCCGAACGTGGAACAGTATCACAAAAGATTCCATCTCCC AACGATTTCAGAACTCTGAGCTCAGAGAGACTCCAGATTTTAAAAAATAATTTGAGTGCTTGGAAACTA TTAGCTTTTTAAGTTCCTTCCAAATATGTTAGTACCTACCCTTTACTTTTTCCCCAAGACCATCTCAGG GTGGAGCATTCTGTCTAAGAGAAGAAAGATAAGGAGGCTCCCACCCACCTCTCCCAAGAGCAGACATTA AACATCTTTGTGCTTTGAAGAGAGTGAATTTTGGATAGTCTTGTGATTCTCAGACTAACTTCCAGAATT ATACTTTAACCCCTCCCAGATATGGTCCGCCTTTGGCATTGTGTGTACATCTGCAGTTTTGCATGGTGG GTTGTTAATATTTCAAATGTGTGGTTTATGAATACGTCTGTATAATCGGCTTCTGGAGTGAAACAGCAA ACCCCAAATCTTCAAAGTTGGAAGGAACTTTAAAAATCATCCGGTCCAATCTCTTTCCTCTTTCTGCCA CCTCCCAAGGCAGAAATCCCCTCTTCAGCTTCTTTTGTAGGTGGGAATCCAGCCTCTGTTAGATATGTC CAGAGATGGAAACTCACTCCCCTACAAAAGATGGAGCTTAATGGAGAAATTGCAACTTTCATTAAAAAA CAAATTCAGATGAAATATCAGTAACTGTCTTGGACAGTGCTGAAATCAGGTGGTTAAACGGGTAAACAA AATATACTGTATTTTGAGAAATGGCACAAAAACAGGCAGTCATCTTTAAGGGCTATGCCTAGGCAAACT ACTAACATGCATTGTGAGAATGCCGTGTATACCTCACGTACTGTGTACTTTGTACATATATTTTACCTT TTATACCTATGTTCGATTTTGTTTTGTTTTGTTTTGTTCTGGCTTTGAGGCTTGTTTTGTTGTCTGTGT CTGTCTGAATAACCTGCGTGTCTAAAACCACGTGAAATGTGAATGATTATTGGCAATATTACCTTGACA GAATCATGGGACTTTGAGAAGAGGGAGGACAGAGGCCTCTGTCGCACTAACGCTCTCGTGGTTGCTCGA CTGTTGTATCTGTGATACATTATCCGACTAAGGACTCTGGGCTGGCAGGGCCTTCTGCCGGGAAAGCTA GAAACACTAGGTTCTTCCTGTACATACGTGTATATATGTGAACAGTGAGATGGCCGTTTCTGACTTGTA GAGAAATTTTAATAAACCTGGTTTCGTAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_025195.4
Synonyms	C8FW; GIG-2; GIG2; SKIP1; TRB-1; TRB1
Summary	Adapter protein involved in protein degradation by interacting with COP1 ubiquitin ligase (PubMed:27041596). The COP1-binding motif is masked by autoinhibitory interactions with the protein kinase domain (PubMed:26455797). Serves to alter COP1 substrate specificity by directing the activity of COP1 toward CEBPA (PubMed:27041596). Binds selectively the recognition sequence of CEBPA (PubMed:26455797). Regulates myeloid cell differentiation by altering the expression of CEBPA in a COP1-dependent manner (By similarity). Controls macrophage, eosinophil and neutrophil differentiation via the COP1-binding domain (By similarity). Interacts with MAPK kinases and regulates activation of MAP kinases, but has no kinase activity (PubMed:15299019, PubMed:26455797).[UniProtKB/Swiss-Prot Function]
Locus ID	10221
MW	74.8

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