TRIB1 (NM_025195) Human 3' UTR Clone
CAT#: SC217203
3' UTR clone of tribbles homolog 1 (Drosophila) (TRIB1) for miRNA target validation
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CNY 5,795.00
货期*
3周
规格
Product images
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经常一起买 (2)
Specifications
Product Data | |
Product Name | TRIB1 (NM_025195) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | C8FW; GIG-2; GIG2; SKIP1; TRB-1; TRB1 |
ACCN | NM_025195 |
Insert Size | 1962 bp |
Sequence Data |
>SC217203 3’UTR clone of NM_025195
The sequence shown below is from the reference sequence of NM_025195. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GACAGTGACATTAGTTCCTTCTTCTGCTAATCCCCAAAACCTCAGAAACCTCATAATTCTTAACACCTG GCATTTCCATTTCTAAAGATGGACAGGCCCTTTGGCGTGGTACCAACCAGATAATGACTGCATCAGGAT GAAAGCTGCTGAACTCGGCATGGCGCCTCCTCTTCTCTGTTGGGATGAGTGACTTTATTGATTTGAGCA GCATATGCTGTGATTGGCTGCCCTGCAAATTTGTTTCCCTTAAGGAACCCTCACCAACTATCTCTGCTG GATTTGGGAGTTCCGCATCTTTTGTGGAGGGCAGAGTATGGACATCTTACACCCGGTGGTCAAGTGTGT AATAAACTTGAGCATTCGAATGGGAGAAAAAGCAAATCGCACAATGACATATTTTGAGTAATAACCGTA TTTTTCACAGGGTGACAAATTGGGCCAATAAATCTGCCATCTTTGAACTCATCTTTGGTGGCTAGACTG CTACGGCAGCTTCTCTGATGGGAAAGTTCCTTTTTTGGCTTAACACTCACCCTTTCTTCACACTCACAT TTACCAATGACTCTGCTCCGTTTTTGGAGCAGACTGTTTTAAGTTGCTCAGGAGCCTGATGGAACCATG AACCGAGACTCTTCTCTGTTTCCTGCCAAGACCTCATCTGCACTAATGCCTTCTCCCTGACCTTGACAC TTCCCCCTTTAGCTATAAAAGCACTTACCAGCCGAACGTGGAACAGTATCACAAAAGATTCCATCTCCC AACGATTTCAGAACTCTGAGCTCAGAGAGACTCCAGATTTTAAAAAATAATTTGAGTGCTTGGAAACTA TTAGCTTTTTAAGTTCCTTCCAAATATGTTAGTACCTACCCTTTACTTTTTCCCCAAGACCATCTCAGG GTGGAGCATTCTGTCTAAGAGAAGAAAGATAAGGAGGCTCCCACCCACCTCTCCCAAGAGCAGACATTA AACATCTTTGTGCTTTGAAGAGAGTGAATTTTGGATAGTCTTGTGATTCTCAGACTAACTTCCAGAATT ATACTTTAACCCCTCCCAGATATGGTCCGCCTTTGGCATTGTGTGTACATCTGCAGTTTTGCATGGTGG GTTGTTAATATTTCAAATGTGTGGTTTATGAATACGTCTGTATAATCGGCTTCTGGAGTGAAACAGCAA ACCCCAAATCTTCAAAGTTGGAAGGAACTTTAAAAATCATCCGGTCCAATCTCTTTCCTCTTTCTGCCA CCTCCCAAGGCAGAAATCCCCTCTTCAGCTTCTTTTGTAGGTGGGAATCCAGCCTCTGTTAGATATGTC CAGAGATGGAAACTCACTCCCCTACAAAAGATGGAGCTTAATGGAGAAATTGCAACTTTCATTAAAAAA CAAATTCAGATGAAATATCAGTAACTGTCTTGGACAGTGCTGAAATCAGGTGGTTAAACGGGTAAACAA AATATACTGTATTTTGAGAAATGGCACAAAAACAGGCAGTCATCTTTAAGGGCTATGCCTAGGCAAACT ACTAACATGCATTGTGAGAATGCCGTGTATACCTCACGTACTGTGTACTTTGTACATATATTTTACCTT TTATACCTATGTTCGATTTTGTTTTGTTTTGTTTTGTTCTGGCTTTGAGGCTTGTTTTGTTGTCTGTGT CTGTCTGAATAACCTGCGTGTCTAAAACCACGTGAAATGTGAATGATTATTGGCAATATTACCTTGACA GAATCATGGGACTTTGAGAAGAGGGAGGACAGAGGCCTCTGTCGCACTAACGCTCTCGTGGTTGCTCGA CTGTTGTATCTGTGATACATTATCCGACTAAGGACTCTGGGCTGGCAGGGCCTTCTGCCGGGAAAGCTA GAAACACTAGGTTCTTCCTGTACATACGTGTATATATGTGAACAGTGAGATGGCCGTTTCTGACTTGTA GAGAAATTTTAATAAACCTGGTTTCGTAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_025195.4 |
Synonyms | C8FW; GIG-2; GIG2; SKIP1; TRB-1; TRB1 |
Summary | Adapter protein involved in protein degradation by interacting with COP1 ubiquitin ligase (PubMed:27041596). The COP1-binding motif is masked by autoinhibitory interactions with the protein kinase domain (PubMed:26455797). Serves to alter COP1 substrate specificity by directing the activity of COP1 toward CEBPA (PubMed:27041596). Binds selectively the recognition sequence of CEBPA (PubMed:26455797). Regulates myeloid cell differentiation by altering the expression of CEBPA in a COP1-dependent manner (By similarity). Controls macrophage, eosinophil and neutrophil differentiation via the COP1-binding domain (By similarity). Interacts with MAPK kinases and regulates activation of MAP kinases, but has no kinase activity (PubMed:15299019, PubMed:26455797).[UniProtKB/Swiss-Prot Function] |
Locus ID | 10221 |
MW | 74.8 |
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