BMI1 (NM_005180) Human 3' UTR Clone
CAT#: SC217171
3' UTR clone of BMI1 polycomb ring finger oncogene (BMI1) for miRNA target validation
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CNY 5,795.00
货期*
3周
规格
Cited in 4 publications. |
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经常一起买 (2)
Specifications
Product Data | |
Product Name | BMI1 (NM_005180) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | flvi-2/bmi-1; FLVI2/BMI1; PCGF4; RNF51 |
ACCN | NM_005180 |
Insert Size | 1972 bp |
Sequence Data |
>SC217171 3’UTR clone of NM_005180
The sequence shown below is from the reference sequence of NM_005180. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AATGGGTCATCAGCAACTTCTTCTGGTTGATACCTGAGACTGTTAAGGAAAAAAATTTTAAACCCCTGA TTTATATAGATATCTTCATGCCATTACAGCTTTCTAGATGCTAATACATGTGACTATCGTCCAATTTGC TTTCTTTTGTAGTGACATTAAATTTGGCTATAAAAGATGGACTACATGTGATACTCCTATGGACGTTAA TTGAAAAGAAAGATTGTTGTTATAAAGAATTGGTTTCTTGGAAAGCAGGCAAGACTTTTTCTCTGTGTT AGGAAAGATGGGAAATGGTTTCTGTAACCATTGTTTGGATTTGGAAGTACTCTGCAGTGGACATAAGCA TTGGGCCATAGTTTGTTAATCTCAACTAACGCCTACATTACATTCTCCTTGATCGTTCTTGTTATTACG CTGTTTTGTGAACCTGTAGAAAACAAGTGCTTTTTATCTTGAAATTCAACCAACGGAAAGAATATGCAT AGAATAATGCATTCTATGTAGCCATGTCACTGTGAATAACGATTTCTTGCATATTTAGCCATTTTGATT CCTGTTTGATTTATACTTCTCTGTTGCTACGCAAAACCGATCAAAGAAAAGTGAACTTCAGTTTTACAA TCTGTATGCCTAAAAGCGGGTACTACCGTTTATTTTACTGACTTGTTTAAATGATTCGCTTTTGTAAGA ATCAGATGGCATTATGCTTGTTGTACAATGCCATATTGGTATATGACATAACAGGAAACAGTATTGTAT GATATATTTATAAATGCTATAAAGAAATATTGTGTTTCATGCATTCAGAAATGATTGTTAAAATTCTCC CAACTGGTTCGACCTTTGCAGATACCCATAACCTATGTTGAGCCTTGCTTACCAGCAAAGAATATTTTT AATGTGGATATCTAATTCTAAAGTCTGTTCCATTAGAAGCAATTGGCACATCTTTCTATACTTTATATA CTTTTCTCCAGTAATACATGTTTACTTTAAAGATTGTTGCAGTGAAGAAAAACCTTTAACTGAGAAATA TGGAAACCGTCTTAATTTTCCATTGGCTATGATGGAATTAATATTGTATTTTAAAAATGCATATTGATC ACTATAATTCTAAAACAATTTTTTAAATAAACCAGCAGGTTGCTAAAAGAAGGCATTTTATCTAAAGTT ATTTTAATAGGTGGTATAGCAGTAATTTTAAATTTAAGAGTTGCTTTTACAGTTAACAATGGAATATGC CTTCTCTGCTATGTCTGAAAATAGAAGCTATTTATTATGAGCTTCTACAGGTATTTTTAAATAGAGCAA GCATGTTGAATTTAAAATATGAATAACCCCACCCAACAATTTTCAGTTTATTTTTTGCTTTGGTCGAAC TTGGTGTGTGTTCATCACCCATCAGTTATTTGTGAGGGTGTTTATTCTATATGAATATTGTTTCATGTT TGTATGGGAAAATTGTAGCTAAACATTTCATTGTCCCCAGTCTGCAAAAGAAGCACAATTCTATTGCTT TGTCTTGCTTATAGTCATTAAATCATTACTTTTACATATATTGCTGTTACTTCTGCTTTCTTTAAAAAT ATAGTAAAGGATGTTTTATGAAGTCACAAGATACATATATTTTTATTTTGACCTAAATTTGTACAGTCC CATTGTAAGTGTTGTTTCTAATTATAGATGTAAAATGAAATTTCATTTGTAATTGGAAAAAATCCAATA AAAAGGATATTCATTTAGAAAATAGCTAAGATCTTTAATAAAAATTTGATATGAAAAGCACAATGTGCA GAAGTTATGGAAAACCTATAGAGGATTACAACAGGTAAACGTTAAAGAGAATACATTGCTGACTTATAG TGATGTGGCTAAGAAGTACATGCTTTGTTGTAAAATTGCTTGAAAGCCCATTGAAAGATGTATCTGTTT ATTTACAGTCTTTGAAGTAAAAGTTACCAATGTTTGCCAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_005180.9 |
Synonyms | flvi-2/bmi-1; FLVI2/BMI1; PCGF4; RNF51 |
Summary | This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015] |
Locus ID | 648 |
MW | 76.2 |
Citations (4)
The use of this cDNA Clones has been cited in the following citations: |
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Regulation of miRNA biogenesis and histone modification by K63-polyubiquitinated DDX17 controls cancer stem-like features
,Kao, SH;Cheng, WC;Wang, YT;Wu, HT;Yeh, HY;Chen, YJ;Tsai, MH;Wu, KJ;,
Cancer Res.
,PubMed ID 30877109
[BMI1]
|
Hinokitiol up-regulates miR-494-3p to suppress BMI1 expression and inhibits self-renewal of breast cancer stem/progenitor cells
,Chen, SM;Wang, BY;Lee, CH;Lee, HT;Li, JJ;Hong, GC;Hung, YC;Chien, PJ;Chang, CY;Hsu, LS;Chang, WW;,
Oncotarget
,PubMed ID 29100291
[BMI1]
|
miR-494-3p Induces Cellular Senescence and Enhances Radiosensitivity in Human Oral Squamous Carcinoma Cells
,Weng, JH;Yu, CC;Lee, YC;Lin, CW;Chang, WW;Kuo, YL;,
Int J Mol Sci
,PubMed ID 27399693
[BMI1]
|
MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells
,Pierpaolo Peruzzi, Agnieszka Bronisz, Michal O. Nowicki, Yan Wang, Daisuke Ogawa, Richard Price, Ichiro Nakano, Chang-Hyuk Kwon, Josie Hayes, Sean E. Lawler, Michael C. Ostrowski, E. Antonio Chiocca, and Jakub Godlewski,
Neuro Oncology, Jun 2013; 10.1093/neuonc/not055.
,PubMed ID 23733246
[BMI1]
|
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