ESE1 (ELF3) (NM_004433) Human 3' UTR Clone

Specifications

Product Data
Product Name	ESE1 (ELF3) (NM_004433) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	EPR-1; ERT; ESE-1; ESX
ACCN	NM_004433
Insert Size	1890 bp
Sequence Data	Insert Sequence (showhide) >SC216864 3’UTR clone of NM_004433 The sequence shown below is from the reference sequence of NM_004433. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAGGAAGAGGTTCTCCAGAGTCGGAACTGAGGGTTGGAACTATACCCGGGACCAAACTCACGGACCACT CGAGGCCTGCAAACCTTCCTGGGAGGACAGGCAGGCCAGATGGCCCCTCCACTGGGGAATGCTCCCAGC TGTGCTGTGGAGAGAAGCTGATGTTTTGGTGTATTGTCAGCCATCGTCCTGGGACTCGGAGACTATGGC CTCGCCTCCCCACCCTCCTCTTGGAATTACAAGCCCTGGGGTTTGAAGCTGACTTTATAGCTGCAAGTG TATCTCCTTTTATCTGGTGCCTCCTCAAACCCAGTCTCAGACACTAAATGCAGACAACACCTTCCTCCT GCAGACACCTGGACTGAGCCAAGGAGGCCTGGGGAGGCCCTAGGGGAGCACCGTGATGGAGAGGACAGA GCAGGGGCTCCAGCACCTTCTTTCTGGACTGGCGTTCACCTCCCTGCTCAGTGCTTGGGCTCCACGGGC AGGGGTCAGAGCACTCCCTAATTTATGTGCTATATAAATATGTCAGATGTACATAGAGATCTATTTTTT CTAAAACATTCCCCTCCCCACTCCTCTCCCACAGAGTGCTGGACTGTTCCAGGCCCTCCAGTGGGCTGA TGCTGGGACCCTTAGGATGGGGCTCCCAGCTCCTTTCTCCTGTGAATGGAGGCAGAGACCTCCAATAAA GTGCCTTCTGGGCTTTTTCTAACCTTTGTCTTAGCTACCTGTGTACTGAAATTTGGGCCTTTGGATCGA ATATGGTCAAGAGGTTGGAGGGGAGGAAAATGAAGGTCTACCAGGCTGAGGGTGAGGGCAAAGGCTGAC GAAGAGGGGAGTTACAGATTTCCTGTAGCAGGTGTGGGCTTACAGACACATGGACTGGGCTGGGAGGCG AGCAAAGGAAGCAGCTGAGACTGTTGGAGAACGCTTACAAGACTTCATGCAAGCAAGGACATGAACTCA GAACACTGAGGTCAGAAGCATCCTGCTGTCATGACACCGCTCGAGTGACCTTGACCTTGACCAAGTCTG TCCTGTTTAGGACTGATTTTTCCTATTAGGCTAGGGTTTGGACCTGATGTTCTCAAGATGTCTAGAATT GCATGGCTGGCCTTGTGGAATAGATGGTTTTGCATTCCAGCCAAGTGTGCTGTAAACTGTATATCTGTA ATATGAATCCCAGCTTTTGAGTCTGACAAAATCAGAGTTAGGATCTTGTAAAGGAAAAAAAAAAAAAAA CAAAACAAAATGGAGATGAGTACTTGCTGAGAAAGAATGAGGGAAGGAGTTGGCATTTGTTGAAAGTGT AGTCTTTTTCTCTTTTTTTTTTAATTGCAACTTTTACTTTAGATTTAGGAGGTCGTGCGCAGGTTTGTT ACATGGGTATATTGTGTGATGCTGAGCTTGGGATGCGAATGATCCTGTCACCCAGGTAGTGAGTATAGC ACCCAGTGAAACTGTAGTCTCATGCCAGGCACTGTGCTAGCCCACTCTGGCTCATTTAATCCTCTCCTA AGAAGAGAGGAGACACAGCGTCCCCATTTGACAGATGCAGAAAGAGGTTCCACAGGTGTGCCTTGATTC TGTCCTAAAACCGTTTCCCGGAAGCTTTTCCTGGTGTGGGCGCTTCTAACCTAATCCTCAATCGATTCC AGAACTATTACTCTGTTTCCACAGTGATACTGTGTCTAGGTTTTAGGGAGGACAGTTCATTGATGTTAC TTAAGAATGCTTTCCAGGTGGAAAGTTCCTTAAGTTTGAGGCTTCAAATTCCATACAGCACATTAAAAT CCCATTCATGAGTTTGAAATACTGCTCTGTTGTCTTGGAAATACCAATCAGATTGTTGGCTGAAGTGAT GTGGATAAAGAAGGGATCTTAGAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004433.5
Synonyms	EPR-1; ERT; ESE-1; ESX
Summary	Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).[UniProtKB/Swiss-Prot Function]
Locus ID	1999
MW	70.1

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