DAB2 (NM_001343) Human 3' UTR Clone

Specifications

Product Data
Product Name	DAB2 (NM_001343) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	DOC-2; DOC2
ACCN	NM_001343
Insert Size	1784 bp
Sequence Data	Insert Sequence (showhide) >SC216311 3’UTR clone of NM_001343 The sequence shown below is from the reference sequence of NM_001343. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGGGATCCATTTGGAAATCCTTTTGCCTAAATTCTGAACTTGGTCTGCAGACCATCCAGAGGAATAAAA AGGTTGGCCTTAGTAGTCAAAAACAAAGCTGATAGCCAGACACGTTCTGATTTCTGCCCTTGTTCCAGC TTTGACGTATTATCTGTTGCCTTATTTCTCATTGCCTCTTCTACTTGTAAAATGCTTTTCACTTTCTGT CTAGGTTAAAGCTAAACTGAATCTATGGCTTTAAATAAATTAAGATCCTAAACTCTCTAGCTTAAGTGT AAATGAAGTACAGTAGTTTCCCTACTGAACCCTGCCTCTTGTGTCCCTGGAACCTTCTAGAACACCTGC CTTCTACCCTCTGGTTGGGAGATGCAGCCACCACATCCCTTCATATCATACTGTTTTGAATAAATTTTC AAATCCTTATTGTTCAGAGTTGTTTGGGGGTTCTGTTTCAGAGCATAAAACCTAAAGGTTATAGTAGAA CAAGGCACCTTCTTAAAAGAAATCTTGCTTCAGACCATCAGTTACAGAGAATTTCTAAAGTAAAATTGA AGCAACTACAACTTCTCCTTAGACACTTTGGAATCTAACCACTTAAGGACCTTTTTAAAGAGATAGCTT CTCTTCTTTCTGAAGATCAATTTCTCCCAAGGCCAAGATTGTCCTTTTCTCCCATTTCTTGCTAGCTAT TGCAAATGAGGGAAGAACATTATTCATCTCTCCTCCCCTTTTTTTTCTGATTCTTTTTTCAGTCAGTTT TGCTCCTGGGTTCAAGTAGTATTACCACCCTTTCACAAGCAACAGACTCTCACAGGGCAAAAAAAAAAA AAAATCTAATGATTCACAGACAGATCTGGAGCCTCTCTTCATTCTCAGTAATTGCTAGTCCCAAGAACT AGAATTGCAAATGGGCACAACCTATATCCTTCCTGTGGAAGAGGAGGCCACTCTCTTGAGCTGAAGTTC CAGAAGAGCAGTTAATGTTCAAGAGAAATTGAACTCAACTCAGCAACAAAGGACTCTATTTTGAAGAGC AACATATCACAAAGCTAAATGTGATTGTGCCAAACACATTAGGTGCTTATTTGGGGTCATGCTAGGCCT TTATCAAGTAACTGGAAAACTTTTCTTGCAGCCACAATCTCAATGTCGTTAGTAGGAAGATAAGAGGGG AGAAAAAGCTGTAGAACAAATGTTTGGGGTTACCATTGAAAATCTAATGTCTGCAATATTTTTCTCCTC ACAACTTGGAAACGTTCCCAGTTCATTTTCAGTCCTGTTGTGAGCACAGTTCTGAAGGGTTTATTATTG TCAAAATAAGTTTTGTTTTGTTTTGTTTATGTTGGGTTTTTAATGTTGTCTCTTGACCCTTAATGCTCA GGTTCTTGTGGGAGTTAATCAGCCACATCCAATGTTACCTTGAGGGGGAAGAAGAGGGTGATGCTCAGA AGCTAAACAAGACAGGGGCCACATGACCCTCTATTGATTAGCCCCAAGTAGAAAGTCCTGTGGTTTTAT GTTTAATGGTAATAGTTGATCATATATGGCATAATTTTCTATCAGCTTCCTACTCAGTCACTATAAACA CAGACTTGAAATAGTACTTTAAATGTCCAAATACCTAAATGTGCTAAACTGGAGGTAACTATTTCTAGG TAGTTGAATTTTTGAAAGTCATGATCAGCCACACAACTGTTTTGTACATACTTATTTTCTCATGCACTT TTCTGTATGCAAATAAAGCTATAAATTTACTCATTTCAATAAACTGGAGTGGCAGAATA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001343.4
Synonyms	DOC-2; DOC2
Summary	This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Locus ID	1601
MW	67.3

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