CHMP2B (NM_014043) Human 3' UTR Clone

Specifications

Product Data
Product Name	CHMP2B (NM_014043) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ALS17; CHMP2.5; DMT1; FTDALS7; VPS2-2; VPS2B
ACCN	NM_014043
Insert Size	1764 bp
Sequence Data	Insert Sequence (showhide) >SC216252 3’UTR clone of NM_014043 The sequence shown below is from the reference sequence of NM_014043. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CGGCAACTCAAGGCTTTAGGAGTAGATTAGTCAAAAGAAGTCATACTATTTTGCTTACTTATAATTATG TAGTATAAACCAAGCACAGTGCAGATTTCTTTTACAAAACACATGTATTTTGCAAAAAAAAAAAAAATG AAGACCATGAGTGAACAGTTGTTTCCTAACCCATGGCTATTTAGAATCTTTTGCCAAAGAATGACAATG ATGCAAAAATGGGAACAGTTTGGATTTTAATTAGAACTGTTTAGGAGTGATGATGTGTAAAAAGTTGAC TTCTCTTTTGCATGGCACAGAGAAATTATATTCCTTACTTCATGTCAGTTTATGTTCTAAATCTTTTTC ACTGAATATAAAAATCTTGTTAAATGCCATTAGGCACCAACTTAAAGAGGGTTGTAAAAATATTAAAAG TATATCGTTAATTCTGTATCTGTTGCTTGTCTTTTGTAAGTGATTATGTGTTATGACCATAGGTGGTTA CAGCTGCCAAATTATTTTTAAATGGTCAAAAAGAAGAGTGCTATTTAAACATCTGTCTTAAACAAAAAC TGTCATAACTTTTCTTTTTTCTTTTTCCATTAGGAGAACATTCTAGTTGGTAAATTTCAAAATGTGCTT GACACCTGCCTTAAATAGCACAGACCTATTGTGCACATCTTTAAATTATTTCAGCTGGCAGAAAAGAAT TACATTTAAAACTGAAATCAAGGCCTCAATACAAAGATTATCCTGGCTCTTTTCTATCTCTGTGGGCCT AATTGAAATATGTACTCTTATTTTAGACACGCCTCTGTTAAAACAGACCAGGTTTTCCTGGTCTCAGAC CTATGATGACTTGTCCCTTTGATGTCACTACTGTGAATTGAATATAATTAGTAAAAATAGACGATGAAT AAATAACACTTTATAGTAAGAAAACAATATATTTTGGCCATCTAAAAATGAGAATTATAATTATATGAA TTATAATTTAAACTGTTTAATTTTGTTTAATGTGTATATTGAATCTTCCAAATTGAAGCCATTATTCTC AATTAAGTACTACAACTATGACAATGCTTGACCTACATTTCTAAAATAAAAATTCACATTTTTTGATAA ATAAACTACAGTTTTACCAGAAATTACTATCTAAATGTGTATTAGCAGTATTTTTTAAGGTGAAATTGC CTTGGTATCTAATGAATGTGTAGACAGGGAGATAAAATGAAGGATTGCCAGACTAGTTAGAATAGAATT TAGGATTAGGTTAGTTTTGAAAAATGATGTTGTAATATATGGGTTCTAACACATCCTACCATAAAAACT GGAGGAGATATGTGTAACCTGGTTAATTTGGGATGGTGGACATTTTGGGCTAATACTGACAAAATACAT CTTAGGACTAGTATACATGTGACACGGATTGCTAGGAGGAATGAAAAACTAAACTGTATAGTTTATATT CCGTAAACCATTTTATAATGTTCAAAGATTAGGTTTTGTTATTGATAGTATTAAATACACAGTTTCTCT TAACAGTGATGGGTGAAAACATTTTACCGGATTATGGAATGTTTACCAGAACATGTTTTGATTCTTGAA TGTACATAATAATGCCATCTAACTTATTTACGTTCTTGTTTACATGTGGGAGCTTTTGTTTTCAAAAAT TATTTTGTTAAAAAATCTCAATAAAGATTTATTATTGTTGTTCTTTTCTTACCTTTTTTGCTCTTTTTG GTTCCTGCTAAAATTAAAAATTTTATGCATATTTGGTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_014043.4
Synonyms	ALS17; CHMP2.5; DMT1; FTDALS7; VPS2-2; VPS2B
Summary	This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration. [provided by RefSeq, Jul 2008]
Locus ID	25978
MW	70.3

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