Pumilio 1 (PUM1) (NM_001020658) Human 3' UTR Clone

Specifications

Product Data
Product Name	Pumilio 1 (PUM1) (NM_001020658) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HSPUM; PUMH; PUMH1; PUML1; SCA47
ACCN	NM_001020658
Insert Size	1735 bp
Sequence Data	Insert Sequence (showhide) >SC216231 3’UTR clone of NM_001020658 The sequence shown below is from the reference sequence of NM_001020658. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATCTGTGGCCCCCCTAATGGTATCATCTGAGGCAGTGTCACCCGCTGTTCCCTCATTCCCGCTGACCTC ACTGGCCCACTGGCAAATCCAACCAGCAACCAGAAATGTTCTAGTGTAGAGTCTGAGACGGGCAAGTGG TTGCTCCAGGATTACTCCCTCCTCCAAAAAAGGAATCAAATCCACGAGTGGAAAAGCCTTTGTAAATTT AATTTTATTACACATAACATGTACTATTTTTTTTAATTGACTAATTGCCCTGCTGTTTTACTGGTGTAT AGGATACTTGTACATAGGTAACCAATGTACATGGGAGGCCACATATTTTGTTCACTGTTGTATCTATAT TTCACATGTGGAAACTTTCAGGGTGGTTGGTTTAACAAAAAAAAAAAGCTTTAAAAAAAAAAGAAAAAA AGGAAAAGGTTTTTAGCTCATTTGCCTGGCCGGCAAGTTTTGCAAATAGCTCTTCCCCACCTCCTCATT TTAGTAAAAAACAAACAAAAACAAAAAAACCTGAGAAGTTTGAATTGTAGTTAAATGACCCCAAACTGG CATTTAACACTGTTTATAAAAAATATATATATATATATATATATATATAATGAAAAAGGTTTCAGAGTT GCTAAAGCTTCAGTTTGTGACATTAAGTTTATGAAATTCTAAAAAATGCCTTTTTTGGAGACTATATTA TGCTGAAGAAGGCTGTTCGTGAGGAGGAGATGCGAGCACCCAGAACGTCTTTTGAGGCTGGGCGGGTGT GATTGTTTACTGCCTACTGGATTTTTTTCTATTAACATTGAAAGGTAAAATCTGATTATTTAGCATGAG AAAAAAAAATCCAACTCTGCTTTTGGTCTTGCTTCTATAAATATATAGTGTATACTTGGTGTAGACTTT GCATATATACAAATTTGTAGTATTTTCTTGTTTTGATGTCTAATCTGTATCTATAATGTACCCTAGTAG TCGAACATACTTTTGATTGTACAATTGTACATTTGTATACCTGTAATGTAAATGTGGAGAAGTTTGAAT CAACATAAACACGTTTTTTGGTAAGAAAAGAGAATTAGCCAGCCCTGTGCATTCAGTGTATATTCTCAC CTTTTATGGTCGTAGCATATAGTGTTGTATATTGTAAATTGTAATTTCAACCAGAAGTAAATTTTTTTC TTTTGAAGGAATAAATGTTCTTTATACAGCCTAGTTAATGTTTAAAAAGAAAAAAATAGCTTGGTTTTA TTTGTCATCTAGTCTCAAGTATAGCGAGATTCTTTCTAAATGTTATTCAAGATTGAGTTCTCACTAGTG TTTTTTTAATCCTAAAAAAGTAATGTTTTGATTTTGTGACAGTCAAAAGGACGTGCAAAAGTCTAGCCT TGCCCGAGCTTTCCTTACAATCAGAGCCCCTCTCACCTTGTAAAGTGTGAATCGCCCTTCCCTTTTGTA CAGAAGATGAACTGTATTTTGCATTTTGTCTACTTGTAAGTGAATGTAACATACTGTCAATTTTCCTTG TTTGAATATAGAATTGTAACACTACACGGTGTACATTTCCAGAGCCTTGTGTATATTTCCAATGAACTT TTTTGCAAGCACACTTGTAACCATATGTGTATAATTAACAAACCTGTGTATGCTTATGCCTGGGCAACT ATTTTTTGTAACTCTTGTGTAGATTGTCTCTAAACAATGTGTGATCTTTATTTTGAAAAATACAGAACT TTGGAATCTG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001020658.2
Synonyms	HSPUM; PUMH; PUMH1; PUML1; SCA47
Summary	This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Locus ID	9698
MW	67.7

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