DFFB (NM_004402) Human 3' UTR Clone

Specifications

Product Data
Product Name	DFFB (NM_004402) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CAD; CPAN; DFF-40; DFF2; DFF40
ACCN	NM_004402
Insert Size	1718 bp
Sequence Data	Insert Sequence (showhide) >SC216045 3’UTR clone of NM_004402 The sequence shown below is from the reference sequence of NM_004402. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CGGAAGCAGCCTGTGCGGAAACGCCAGTGACACGTACACACCACGTCCTGGTCTTTGTTTGAGGCCTGA CGTGGGCATCATTTTAACAGGTGCCTTTTTTGTTTTTTTGTTTTTCGTTTTTTTGGTCACTCCAGTAGC TCCTGGAAAAAACCTTAAAAAATGTTTCCTCCAAATCTGATTTCATTACATTTCTGAATTGTTGGGGTT TTTTTTGTTGTTTTGTTTTGTTTTGTAGATGGAGTTTCACTTTTGTTGCCCAGGCTGGAGTGTAGTGGC GCGATCTCGGCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGTGCCACCACGCCCGGCTAATGTTTG TATTTTTAGTAGAGACGGGGTTTCACCATGTTGGTCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATC CGCCCACCTCAGCCTCCCAAAGTGCTGGGATGACAGGTGTGAGCCACTGCGCCCAGCCTGAATCATTTC TTATACCTTCTGACAGCCCAACTTCCAGAGGACAGCTCTGGGGTACTCGTTGGATGTCTGTGAGTACCT GGTCATACGGGTCAGTAGGGATAAGAATTGTCTCTGGGCTGAGGAATTCTTCTGTTCTCTGGTTTCACC AGCGTTGGGTTTGCTCATGTAATGTGGTCACCATACTCAAATGGTGTCATGGCTGAAGTTGGCCACCTT GCTTGAGGGACAAGTTGTTTATGTATCAGCTCTCTGCTGGGTCTCCCTTTCCATGGCAAATGGGCAGCT CCATCCTCTTGACTCTTCTAAATGCCCAAAAGAGGTGTCATGCTTTGGGGGTACGATGTTTATACTCCG TAAAGAACATACAAGGACATTCACTGCTGATTTTTTTTTTTGTTTGTTTGAGACAGGGTCTCACTCTGT CGCTCAGGCTGGAGTGCAGTGATGCAATCTTGGCTCACTGCAACCTCCGCCTCTCAGGTTCAAGTGGTT CTCCTTCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCACCTACCACCAGGGCCAGCTAATTTTTGTAT GTTTAGTAGAAACGGGGTTTCACCATGTTGGCCAGGCTGTTCTCGAACTCCTGACCTCAGGTGATCTGC CCGCCTCGGTCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGCACCTGACCTGCTGAATTGTTTA TAATGGCAAGAAATAGGAAACCCCCCAATGTCTGTTGAACAGCTATCACGTTGAACCACGTGAAACTGC TGTTTTCTAGGCCAAAAATGGTGAGCGATCATTTATTTCATGATTCAACCTGATACATTTACATAGTGC AAAACTGTGTCACAGTTTCAGGCTTTTATGAGGAAAGCGTTTCTGTGTAGAAACTGGAAGCTGTTCAGG GCATCGGCAGCTGAACCCTGCTCCGTTGGTCAGCGTTACTATCATCTCGGATCATATGGAGCTCATGTC AGCCGTGTGGGTGGCGGGTGCACAGAGACGGTCTGGAAGGAAACACGCGGATCTGAACAGCAGTAATCC TGGGGGATACGGGGGTTGGGCTAGATTACAGAGGGCTCATTTTCTACGTCATGTATTTTATGATACTTG AATTTTTTGAAATGGGCATTTATTTTATAACATGTTAAAATGTACTTTTTAAATTAAGTCATTTTGTAA TATTTGAATTTTTACATTTGTTGTACAATCAGGAAAAGCAATAAAGATTTTTCAAAAATAGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004402.4
Synonyms	CAD; CPAN; DFF-40; DFF2; DFF40
Summary	Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of some of these variants has not been determined. [provided by RefSeq, Sep 2013]
Locus ID	1677
MW	64.2

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