SIRT3 (NM_012239) Human 3' UTR Clone
CAT#: SC215986
3' UTR clone of sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae) (SIRT3) transcript variant 1 for miRNA target validation
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CNY 5,795.00
货期*
3周
规格
Cited in 1 publication. |
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经常一起买 (2)
Specifications
Product Data | |
Product Name | SIRT3 (NM_012239) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | SIR2L3 |
ACCN | NM_012239 |
Insert Size | 1698 bp |
Sequence Data |
>SC215986 3’UTR clone of NM_012239
The sequence shown below is from the reference sequence of NM_012239. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACTGGGAAGCTTGATGGACCAGACAAATAGGATGATGGCTGCCCCCACACAATAAATGGTAACATAGGA GACATCCACATCCCAATTCTGACAAGACCTCATGCCTGAAGACAGCTTGGGCAGGTGAAACCAGAATAT GTGAACTGAGTGGACACCCGAGGCTGCCACTGGAATGTCTTCTCAGGCCATGAGCTGCAGTGACTGGTA GGGCTGTGTTTACAGTCAGGGCCACCCCGTCACATATACAAAGGAGCTGCCTGCCTGTTTGCTGTGTTG AACTCTTCACTCTGCTGAAGCTCCTAATGGAAAAAGCTTTCTTCTGACTGTGACCCTCTTGAACTGAAT CAGACCAACTGGAATCCCAGACCGAGTCTGCTTTCTGTGCCTAGTTGAACGGCAAGCTCGGCATCTGTT GGTTACAAGATCCAGACTTGGGCCGAGCGGTCCCCAGCCCTCTTCATGTTCCGAAGTGTAGTCTTGAGG CCCTGGTGCCGCACTTCTAGCATGTTGGTCTCCTTTAGTGGGGCTATTTTTAATGAGAGAAAATCTGTT CTTTCCAGCATGAAATACATTTAGTCTCCTCAAAGGGACTGCAGGTGTTGACATGAGTTGGAAAGGGAA CCCTGGGATACGTGGCGTCCCCTCTATTGGAACAGTCTGAGGACTGAAGGCATTTGTCCCTGGATTTAT TGGAGACGGCCCAGCTCCTCCCTCTGAAGGTGGTCACATTCTGTTGACTCTCCATACTCAGCCTCTCCT CCAGAAACAGATCTGTTCCAGAACATTCCAGCACTTTCTATCTGGCCTCCTTGTCCCCACACTACGCCC CCCCACCCTCGCCAGGGCTTCCTCTAGTGACACTGTTAGAGCTAATCTCTGAGACAGGGAAGGCATTAC TCACTTAAAACCCAGGCTGAGTCCTGGCCACCTGCTGGATTGTGACATAGGAGGTGGAATCCACTGAAC TGCTACTTCTGCACAGGCTCCTTCTCCTGGGGCTGTACCCAGGCCCAGCCCTGATGGCTCACCCTGTCA GGCACCAGCTGCTCCCTCCTGGGCTCTCACCCACCTGCACATCCTCCTTCCTAGCATCACATTACCTGC GTGTTTCCCCAGACAAAAGCACTTCCCATTCTTGAACCTTGCCTACCCTGGGCTGAGCTGACGGCAATA GATTTAATGACAGTGACTCCCAGGAAGGGGGTCCTGTGACTTTGCGCCTTAATAAGAACAAAAGGTGGA ATTGGTGACCTAGGAAAACTGTTGAATTCTAAAAAGAATGAAGTTAGTTTCTAACCCTAGTTAATGTTC CTTTTTTATTTTTTGAGTCTTGCCCTGTCACTCAGGGTGGAGTGCGGTGTTATGATCTCAGCTCACTGC AACTTCCGCCTCCCGGGTTTAAGCGATTCTCCTGGGTAGCTGGGATTACAGGTGTGTCCCACCACACCT AGCACATGGGCATATTTGTAATAGAGACAAGGTTTTGCTATGTTGGCCAGGCTGGTCTCGAACTCCTGG CTTCAAGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGTGCCTGGC CCCTTTATTTGATAATTTACACATACATTTTTGTCCAAAACTCTTCTTTATTTCAAGATGATGTTTCTG TGGCTATGTGTGGTATGTGGTATAAATCTCAATCTATGGTCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_012239.6 |
Synonyms | SIR2L3 |
Summary | SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control. [provided by RefSeq, May 2019] |
Locus ID | 23410 |
MW | 63.6 |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Oroxylin A promotes PTEN-mediated negative regulation of MDM2 transcription via SIRT3-mediated deacetylation to stabilize p53 and inhibit glycolysis in wt-p53 cancer cells
,null,
Journal of Hematology & Oncology
,PubMed ID 25902914
[SIRT3]
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