LRRC8A (NM_001127244) Human 3' UTR Clone

Specifications

Product Data
Product Name	LRRC8A (NM_001127244) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AGM5; HsLRRC8A; LRRC8; SWELL1
ACCN	NM_001127244
Insert Size	1698 bp
Sequence Data	Insert Sequence (showhide) >SC215962 3’UTR clone of NM_001127244 The sequence shown below is from the reference sequence of NM_001127244. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTGTGGAGGGCTGACAAGGAGCAGGCCTGAGCGAGGCCGGCCCAGCACAGCAAGCAGCAGGACCGCTGC CCAGTCCTCAGGCCCGGAGGGGCAGGCCTAGCTTCTCCCAGAACTCCCGGACAGCCAGGACAGCCTCGT GGCTGGGCAGGAGCCTGGGGCCGCTTGTGAGTCAGGCCAGAGCGAGAGGACAGTATCTGTGGGGCTGGC CCCTTTTCTCCCTCTGAGACTCACGTCCCCCAGGGCAAGTGCTTGTGGAGGAGAGCAAGTCTCAAGAGC GCAGTATTTGGATAATCAGGGTCTCCTCCCTGGAGGCCAGCTCTGCCCCAGGGGCTGAGCTGCCACCAG AGGTCCTGGGACCCTCACTTTAGTTCTTGGTATTTATTTTTCTCCATCTCCCACCTCCTTCATCCAGAT AACTTATACATTCCCAAGAAAGTTCAGCCCAGATGGAAGGTGTTCAGGGAAAGGTGGGCTGCCTTTTCC CCTTGTCCTTATTTAGCGATGCCGCCGGGCATTTAACACCCACCTGGACTTCAGCAGAGTGGTCCGGGG CGAACCAGCCATGGGACGGTCACCCAGCAGTGCCGGGCTGGGCTCTGCGGTGCGGTCCACGGGAGAGCA GGCCTCCAGCTGGAAAGGCCAGGCCTGGAGCTTGCCTCTTCAGTATTTGTGGCAGTTTTAGTTTTTTGT TTTTTTTTTTTTAATCAAAAAACAATTTTTTTAAAAAAAAAGCTTTGAAAATGGATGGTTTGGGTATTA AAAAGAAAAAAAAAACTTAAAAAAAAAAAGACACTAACGGCCAGTGAGTTGGAGTCTCAGGGCAGGGTG GCAGTTTCCCTTGAGCAAAGCAGCCAGACGTTGAACTGTGTTTCCTTTCCCTGGGCGCAGGGTGCAGGG TGTCTTCCGGATCTGGTGTGACCTTGGTCCAGGAGTTCTATTTGTTCCTGGGGAGGGAGGTTTTTTTGT TTGTTTTTTGGGTTTTTTTGGTGTCTTGTTTTCTTTCTCCTCCATGTGTCTTGGCAGGCACTCATTTCT GTGGCTGTCGGCCAGAGGGAATGTTCTGGAGCTGCCAAGGAGGGAGGAGACTCGGGTTGGCTAATCCCC GGATGAACGGTGCTCCATTCGCACCTCCCCTCCTCGTGCCTGCCCTGCCTCTCCACGCACAGTGTTAAG GAGCCAAGAGGAGCCACTTCGCCCAGACTTTGTTTCCCCACCGCCTGCGGCATGGGTGTGTCCAGTGCC ACCGCTGGCCTCCGCTGCTTCCATCAGCCCTGTCACCACCTGGTCCTTCATGAAGAGCAGACACTTAGA GGCTGGTCGGGAATGGGGAGGTCGCCCCTGGGAGGGCAGGCGTTGGTTCCAAGCCGGTTCCCGTCCCTG GCGCCTGGAGTGCACACAGCCCAGTCGGCACCTGGTGGCTGGAAGCCACCCTGCTTTAGATCACTCGGG TCCCCACCTTAGAAGGGTCCCCGCCTTAGATCAATCACGTGGACACTAAGGCACGTTTTAGAGTCTCTT GTCTTAATGATTATGTCCATCCGTCTGTCCGTCCATTTGTGTTTTCTGCGTCGTGTCATTGGATATAAT CCTCAGAAATAATGCACACTAGCCTCTGACAACCATGAAGCAAAAATCCGTTACATGTGGGTCTGAACT TGTAGACTCGGTCACAGTATCAAATAAAATCTATAACAGAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001127244.2
Synonyms	AGM5; HsLRRC8A; LRRC8; SWELL1
Summary	This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
Locus ID	56262
MW	62.7

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