PDGF beta (PDGFB) (NM_002608) Human 3' UTR Clone

Specifications

Product Data
Product Name	PDGF beta (PDGFB) (NM_002608) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	c-sis; IBGC5; PDGF-2; PDGF2; SIS; SSV
ACCN	NM_002608
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC215947 3’UTR clone of NM_002608 The sequence shown below is from the reference sequence of NM_002608. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACGGCACTGAAGGAGACCCTTGGAGCCTAGGGGCATCGGCAGGAGAGTGTGTGGGCAGGGTTATTTAAT ATGGTATTTGCTGTATTGCCCCCATGGGGTCCTTGGAGTGATAATATTGTTTCCCTCGTCCGTCTGTCT CGATGCCTGATTCGGACGGCCAATGGTGCTTCCCCCACCCCTCCACGTGTCCGTCCACCCTTCCATCAG CGGGTCTCCTCCCAGCGGCCTCCGGCGTCTTGCCCAGCAGCTCAAGAAGAAAAAGAAGGACTGAACTCC ATCGCCATCTTCTTCCCTTAACTCCAAGAACTTGGGATAAGAGTGTGAGAGAGACTGATGGGGTCGCTC TTTGGGGGAAACGGGCTCCTTCCCCTGCACCTGGCCTGGGCCACACCTGAGCGCTGTGGACTGTCCTGA GGAGCCCTGAGGACCTCTCAGCATAGCCTGCCTGATCCCTGAACCCCTGGCCAGCTCTGAGGGGAGGCA CCTCCAGGCAGGCCAGGCTGCCTCGGACTCCATGGCTAAGACCACAGACGGGCACACAGACTGGAGAAA ACCCCTCCCACGGTGCCCAAACACCAGTCACCTCGTCTCCCTGGTGCCTCTGTGCACAGTGGCTTCTTT TCGTTTTCGTTTTGAAGACGTGGACTCCTCTTGGTGGGTGTGGCCAGCACACCAAGTGGCTGGGTGCCC TCTCAGGTGGGTTAGAGATGGAGTTTGCTGTTGAGGTGGCTGTAGATGGTGACCTGGGTATCCCCTGCC TCCTGCCACCCCTTCCTCCCCACACTCCACTCTGATTCACCTCTTCCTCTGGTTCCTTTCATCTCTCTA CCTCCACCCTGCATTTTCCTCTTGTCCTGGCCCTTCAGTCTGCTCCACCAAGGGGCTCTTGAACCCCTT ATTAAGGCCCCAGATGATCCCAGTCACTCCTCTCTAGGGCAGAAGACTAGAGGCCAGGGCAGCAAGGGA CCTGCTCATCATATTCCAACCCAGCCACGACTGCCATGTAAGGTTGTGCAGGGTGTGTACTGCACAAGG ACATTGTATGCAGGGAGCACTGTTCACATCATAGATAAAGCTGATTTGTATATTTATTATGACAATTTC TGGCAGATGTAGGTAAAGAGGAAAAGGATCCTTTTCCTAATTCACACAAAGACTCCTTGTGGACTGGCT GTGCCCCTGATGCAGCCTGTGGCTTGGAGTGGCCAAATAGGAGGGAGACTGTGGTAGGGGCAGGGAGGC AACACTGCTGTCCACATGACCTCCATTTCCCAAAGTCCTCTGCTCCAGCAACTGCCCTTCCAGGTGGGT GTGGGACACCTGGGAGAAGGTCTCCAAGGGAGGGTGCAGCCCTCTTGCCCGCACCCCTCCCTGCTTGCA CACTTCCCCATCTTTGATCCTTCTGAGCTCCACCTCTGGTGGCTCCTCCTAGGAAACCAGCTCGTGGGC TGGGAATGGGGGAGAGAAGGGAAAAGATCCCCAAGACCCCCTGGGGTGGGATCTGAGCTCCCACCTCCC TTCCCACCTACTGCACTTTCCCCCTTCCCGCCTTCCAAAACCTGCTTCCTTCAGTTTGTAAAGTCGGTG ATTATATTTTTGGGGGCTTTCCTTTTATTTTTTAAATGTAAAATTTATTTATATTCCGTATTTAAAGTT GTAAAAAAAAATAACCACAAAACAAAACCAAATGAATCCGCCGGAGGTCTGTCTGTTGGCATCGTGCGT GACAATTAACCTTTCTGCCTTGGCAGGATGTGCCGACAGCTTGCGGCGTGTTCCTCTCACTCTGGGAGC CTCAGGCGTGATCTCACACACTGGCGTGCACATACACACACACACACATACATGCTCACACATGCGTGC ACATACACGCAGGCCTGCAACTTGGGGGAGGCCTCTGTCTGGCGGGAAGAAGAGACACACAGGCTACTC TGTTGGTCTTGGTCCTGGCACAGCTCCTGACACGTGGACTTGTGCGTGTCTCTGGCAGTGACGAGAGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002608.4
Synonyms	c-sis; IBGC5; PDGF-2; PDGF2; SIS; SSV
Summary	This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit A. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with dermatofibrosarcoma protuberans, a rare skin tumor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Locus ID	5155
MW	73.7

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