Kir6.2 (KCNJ11) (NM_000525) Human 3' UTR Clone

Specifications

Product Data
Product Name	Kir6.2 (KCNJ11) (NM_000525) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BIR; HHF2; IKATP; KIR6.2; MODY13; PHHI; PNDM2; TNDM3
ACCN	NM_000525
Insert Size	1701 bp
Sequence Data	Insert Sequence (showhide) >SC215940 3’UTR clone of NM_000525 The sequence shown below is from the reference sequence of NM_000525. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TTCAGCATCTCTCCAGATTCCCTGTCCTGAGCCATGGTCTCTCGGGCCCCCCACACGCGTGTGTACACA CGGACCATGTGGTATGTAGCCCGGCCAGGGCCTGGTGTGAGGCTGGGCCAGCCTCAGCTCAGCCTCCCC CTGCTGCTCATCCAGGGTGTTACAAGGCACTTGTCACTATGCTATTTCTGGCCTCAGCAGGAACCTGTA CTGGGTTATTTTTGTCCCTGCTCCTCCCAACCCAATTCAGGACTGGCTCACCCCTCTCCCCCGCCCAAG GCTGCAGAGGCTGTGGGAGGTACTGGGCCCTAGAGCTGTGCGTCCAGCCAGTCCTGGGTCCCCACGATT GACCAGCCACACTCTGGGCCGGTGGCTGGGGAAGAACAATCCCCGAGGGCTGCTGCTTTGCGTCTGTGG CTCCAAGAAGTGCCTGTGGTCAGGCCCCAGCTCTACTTGGTCCCTGAAAAAGCACCTGGCTAAGGGCTG GGCCTGGCCAGCAGGGAGGGCAGTTGATGAGAGAGGGTGTTCCCGCTGGAGGGTTGGTGCTGTGGAGCC TACACCGGCAGGGACAGCCTGGGGCTGACAGGGCTCCCCTCCGAGGGCCAGTTTCAGGTCTGGAAGGGG AGGAAGCAGGGGAAGGTGACCTGAGGAGGCTCGGCTTTGTAGAGCCCCGCTCAGGCACAGGGAGGAGGA GATGCCAGGGCTCCTGCCTTTTGCCACATCGGCCTCGTGCAGTGAGGGCTCTGTGGGCTGGGGCTGCTG CCCCTGCCTACCTCCTGCCTGTCCCCAGAGGCTGAGGAGAGGGGGTACTGTGCCCACCACACATGATTA GGCCTCAGACCCAACTCTGGTCCTGGCTCCACAACAGTGGCTGCCACTCACTTTGTCCAGAAGGTGGCT TGGGGGTGGATATCTTTGGGTTGCTGGAAAAGGTGTGGGAAGGTTCAGGATGGTGGGAGGGACTGAGGT CCCTGAGGTGAAGAGGCCCTTGGTCCTGACGGGTTTGACCCGTGCCTGGACCCTTGGAGCAGTGTTGTG TGAACTTGCCTAGAACTCTGCCTTCTCCGTTGTCAATAAAGCCTCCCCCTCATGACCTAAACTCTGGGC TTTTCTTGCTGGGGAGGCAGCAAGCATGCTGGTGGGAAGGGAGGCAGGGACTGGCAGCTGCCACCCCCT TCAAGAGGCGCCATAGACCCTAGCGGGGAGGGCAGGGGAGGGACGGAAGGCTGGCACCTCTTCCACCAG TTCAGGGGGACTTTCCCCTCTCCTGTCTCAGGTGGCCCAGCCCTGTCAGCCTGTCTGGCCAACTCAGCC TTTGGGCACTCACCAGGCTTTGCAGCCCTGGGCTCTGTCTCTACTCCCAGGGACCTGCTGGAAGGCTGG AGTGCCCAGGGAGAGGTATAGAGGTGTCATAGGCATTAGTGTAGTAATTGGAGCACTAACTCTCGAGCC AACTGCCTGGGTTCGAATCCTGGCTCTAGCTGTATGACTTTTGTCAAGTAACTTAGCCTCTCTGTGTCT CAGTTGCCTCTTCTATAACATGGATGCTAATAGTACCTACCTCATAGAATTGTTTTGGAAGTAAATGAA AAATATGTAAAATGCTGAAGTGCCTGGTCTACAGTAAGTGCTCAATAAATGTTAACTATTGTGATTGCT GCTGAATCAGCTACATGCTGAGGAAACGGCCAAACAAGTGTTAAA AGCGGACCGACTTACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCC CAACCTGCCATCACGAGATTTCGATTCCACCGCCGC
Restriction Sites	SgfI-RsrII
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000525.4
Synonyms	BIR; HHF2; IKATP; KIR6.2; MODY13; PHHI; PNDM2; TNDM3
Summary	Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2009]
Locus ID	3767
MW	60.1

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