Adducin 2 (ADD2) (NM_017488) Human 3' UTR Clone

CAT#: SC215800

3' UTR clone of adducin 2 (beta) (ADD2) transcript variant beta-4 for miRNA target validation



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CNY 5,795.00


货期*
3周

规格
    • 10 ug

Product images

经常一起买 (2)
Firefly luciferase assay kit, 150 assays
    • 1 kit

CNY 1,520.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00

Specifications

Product Data
Product Name Adducin 2 (ADD2) (NM_017488) Human 3' UTR Clone
Vector pMirTarget
Synonyms ADDB
ACCN NM_017488
Insert Size 2000 bp
Sequence Data
>SC215800 3’UTR clone of NM_017488
The sequence shown below is from the reference sequence of NM_017488. The complete sequence of this clone may contain minor differences, such as SNPs.
Blue=Stop Codon Red=Cloning site

GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
CGAAGGAGGCAGAGACAAAGAGCCCTTTAGTCTCTCCTTCCAAGTCTTTAGAGGAAGGTACTAAGAAGA
CAGAAACAAGCAAAGCCGCCACCACAGAGCCCGAAACAACCCAGCCGGAAGGGGTGGTGGTCAACGGGA
GGGAGGAGGAGCAGACGGCAGAGGAAATCCTCAGCAAAGGCCTGAGCCAGATGACCACCAGTGCTGACA
CGGATGTTGATACCTCTAAGGACAAAACCGAGTCGGTCACCAGCGGCCCCATGTCCCCAGAGGGCTCAC
CTTCCAAGTCTCCCTCAAAGAAGAAAAAGAAATTCCGAACCCCCTCCTTCCTGAAAAAGAGCAAAAAGA
AGGAGAAAGTGGAGTCCTGATTCATGACACCCTTGGGCTCCCTCCTGCCTCCTCTCTCTCCTCCCCTTC
CCTTCTCCCATCTCTGTCCCTGCAAGCACAGGGCTAAGGAGGGATAGAGTAGGACCCTGGACCACATTC
GGAAGGGGAACTTAGAGATCACCCGACCAACCCTTCGTTTTACAGTTGCCCAAGAGAAATCAGGTGACT
TGCCCAAGGTCACACAGCTAGTTAGCGGCAGAGCCTGCACTCGAATTCAGGTCTCCTGACTTCCAGTCC
AGTGCTCCTTCTACTACACAACACTGCCTAGTTGTGGGCTGCCTTTGTTTGGATGCTGTCCACCAATCT
GAGCCTAGGGCAAGAAGGCCAGAAATGGGCCGTGAGCTCTCACAGGCTCAGACTAAATCAGAGGTCAAG
GCTTCCCCTGAGTAAGGTCCATTTCTTCCCAGGAATCCAATCTCCTGTGGATGGAGCTATCTCTACATT
TAAAAATCTCTTCTCTTTTCCACTTTGGGTCCCTGCCCTGCTGCTCAAAGTGACTAGCCAAATTGACCC
CTCCAACAGAAAGTAATCTTTGTTCCCAAGGGCTGATGGCTTAGCTTGTACTACCCCAAACATTAACCC
TGAGCTTTCTTCATGGAACCTCTTGAATGATGGATGGAAGAGCTATAAGAGGTGGTAGGCATAGGGGCA
AGCCATGTAAGCTGAGGATTGGGGATGGTTTCATCAACATAAGAGGCCAGGAACTTGACCCCTTTGAAT
TGTGCATCTCAGGCACTTCAAAACTAAAACCAAATTTAGCATAGGAAAAAGTTGTTTAATGCTCAGGGC
AGAAATTTGGGGAAGTTGAAATCCTCTGTTGGCTTTGGGTTGTATAAGGAGGATCAAAACAACAGAGGA
AATGCTGACTTTCTAGCTTTGCATGACACCTGGAGCAATGCACTGTACCTGCCTCACTCCTGTCCAGTG
GTCAGGTTTCCCCTGACCTTCCCTCACCCCCAGAAACACTTGCTTACAGACCGAAACTGGCATCTTACT
CTTGGCACCTTGACTTGCACCCTCTGAGGTTCCAACTCAGTCATTCTTTGTCCAGCAGAGGAGAATCAG
AAATGAGCCCTTCAGGATTAATCCTCTTGCACCAGCTCTCAGAGAAATGCTGGGTATCCCTGTCCTTGT
CCCTATCTGTCCATCCTGGGGCCTGGTAATGGCCACAGTTATTGTTTTAAATGCCAACACTGTCTTCTC
ATGTTCTTCCGTGGGGCATTGATTAATGAGCATTTGTTGGCTCCTAAAAATTAGACAATCCATTCTCTT
GAAAGCACCGTGTCTTGAAAGAATATTTTTCCTTTTGATCTGACTATCGTGAAAATATTTTTGAAAGTT
CTTAATCATAGTTTTCCACTTTTGAGCACTTGCTATCTATAGACACTGTGCAGGCTTCACATACATTAC
ATTCTTTAACCCTCACAGTAATCCTTTGAGGGGGGTAAGATCATTCCCATTTTGTGGGTGAGGAAATTG
ACCCCCTAAAATGATAATTGACTTGTCCCAGCTGACTTGGCTAGAAAGATCTGGATCCTGGATTTGAAT
CCAGGTCAGTCTGAGTCCAGAGCCCTTGCTCTTAACAGCTATGGTGAACAGACAACTTTAATCCCCAG
ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites SgfI-MluI     
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq NM_017488.4
Synonyms ADDB
Summary Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010]
Locus ID 119
MW 74.9
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