RTN3 (NM_201430) Human 3' UTR Clone

Specifications

Product Data
Product Name	RTN3 (NM_201430) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ASYIP; HAP; NSPL2; NSPLII; RTN3-A1
ACCN	NM_201430
Insert Size	1637 bp
Sequence Data	Insert Sequence (showhide) >SC215720 3’UTR clone of NM_201430 The sequence shown below is from the reference sequence of NM_201430. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATAGTTATAACGTCGTTACTTGTACTATGAAGGAAAATACTCAGTGTCAGCTTGAGCCTGCATTCCAAG CTTTTTTTTTAATTTGGTGTTTTCTCCCATCCTTTCCCTTTAACCCTCAGTATCAAGCACAAAAATTGA TGGACTGATAAAAGAACTATCTTAGAACTCAGAAGAAGAAAGAATCAAATTCATAGGATAAGTCAATAC CTTAATGGTGGTAGAGCCTTTACCTGTAGCTTGAAAGGGGAAAGATTGGAGGTAAGAGAGAAAATGAAA GAACACCTCTGGGTCCTTCTGTCCAGTTTTCAGCACTAGTCTTACTCAGCTATCCATTATAGTTTTGCC CTTAAGAAGTCATGATTAACTTATGAAAAAATTATTTGGGGACAGGAGTGTGATACCTTCCTTGGTTTT TTTTTGCAGCCCTCAAATCCTATCTTCCTGCCCCACAATGTGAGCAGCTACCCCTGATACTCCTTTTCT TTAATGATTTAACTATCAACTTGATAAATAACTTATAGGTGATAGTGATAATTCCTGATTCCAAGAATG CCATCTGATAAAAAAGAATAGAAATGGAAAGTGGGACTGAGAGGGAGTCAGCAGGCATGCTGCGGTGGC GGTCACTCCCTCTGCCACTATCCCCAGGGAAGGAAAGGCTCCGCCATTTGGGAAAGTGGTTTCTACGTC ACTGGACACCGGTTCTGAGCATTAGTTTGAGAACTCGTTCCCGAATGTGCTTTCCTCCCTCTCCCCTGC CCACCTCAAGTTTAATAAATAAGGTTGTACTTTTCTTACTATAAAATAAATGTCTGTAACTGCTGTGCA CTGCTGTAAACTTGTTAGAGAAAAAAATAACCTGCATGTGGGCTCCTCAGTTATTGAGTTTTTGTGATC CTATCTCAGTCTGGGGGGGAACATTCTCAAGAGGTGAAATACAGAAAGCCTTTTTTTCTTGATCTTTTC CCGAGATTCAAATCTCCGATTCCCATTTGGGGGCAAGTTTTTTTCTTCACCTTCAATATGAGAATTCAG CGAACTTGAAAGAAAAATCATCTGTGAGTTCCTTCAGGTTCTCACTCATAGTCATGATCCTTCAGAGGG AATATGCACTGGCGAGTTTAAAGTAAGGGCTATGATATTTGATGGTCCCAAAGTACGGCAGCTGCAAAA AGTAGTGGAAGGAAATTGTCTACGTGTCTTGGAAAAATTAGTTAGGAATTTGGATGGGTAAAAGGTACC CTTGCCTTACTCCATCTTATTTTCTTAGCCCCCTTTGAGTGTTTTAACTGGTTTCATGTCCTAGTAGGA AGTGCATTCTCCATCCTCATCCTCTGCCCTCCCAGGAAGTCAGTGATTGTCTTTTTGGGCTTCCCCTCC AAAGGACCTTCTGCAGTGGAAGTGCCACATCCAGTTCTTTTCTTTTGTTGCTGCTGTGTTTAGATAATT GAAGAGATCTTTGTGCCACACAGGATTTTTTTTTTTTTTTAAGAAAAACCTATAGATGAAAAATTACTA ATGAAACTGTGTGTACGTGTCTGTGCGTGCAACATAAAAATACAGTAGCACCTAAGGAGCTTGAATCTT GGTTCCTGTAAAATTTCAAATTGATGTGGTATTAATAAAAAAAAAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_201430.3
Synonyms	ASYIP; HAP; NSPL2; NSPLII; RTN3-A1
Summary	This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12. [provided by RefSeq, May 2012]
Locus ID	10313
MW	62.6

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.