NQO1 (NM_000903) Human 3' UTR Clone

Specifications

Product Data
Product Name	NQO1 (NM_000903) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	DHQU; DIA4; DTD; NMOR1; NMORI; QR1
ACCN	NM_000903
Insert Size	1605 bp
Sequence Data	Insert Sequence (showhide) >SC215462 3’UTR clone of NM_000903 The sequence shown below is from the reference sequence of NM_000903. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACTGACAACCAGATCAAAGCTAGAAAATGAGATTCCTTAGCCTGGATTTCCTTCTAACATGTTATCAAA TCTGGGTATCTTTCCAGGCTTCCCTGACTTGCTTTAGTTTTTAAGATTTGTGTTTTTCTTTTTCCACAA GGAATAAATGAGAGGGAATCGACTGTATTCGTGCATTTTTGGATCATTTTTAACTGATTCTTATGATTA CTATCATGGCATATAACCAAAATCCGACTGGGCTCAAGAGGCCACTTAGGGAAAGATGTAGAAAGATGC TAGAAAAATGTTCTTTAAAGGCATCTACACAATTTAATTCCTCTTTTTAGGGCTAAAGTTTTAGGGTAC AGTTTGGCTAGGTATCATTCAACTCTCCAATGTTCTATTAATCACCTCTCTGTAGTTTATGGCAGAAGG GAATTGCTCAGAGAAGGAAAAGACTGAATCTACCTGCCCTAAGGGACTTAACTTGTTTGGTAGTTAGCC ATCTAATGCTTGTTTATGATATTTCTTGCTTTCAATTACAAAGCAGTTACTAATATGCCTAGCACAAGT ACCACTCTTGGTCAGCTTTTGTTGTTTATATACAGTACACAGATACCTTGAAAGGAAGAGCTAATAAAT CTCTTCTTTGCTGCAGTCATCTACTTTTTTTTTAATTAAAAAAAATTTTTTTTTGAAGCAGTCTTGCTC TGTTACCCAGGCTGGAGTGCAGTGGTGTGATCTCGGCTCACTGCAACCTCTGCCTCCCAGGTTCCAGCA ATTCTCCTGCCTCAGCCTCCCTAGTAGCTGGGATGACAGGCGCCTGCCATCATGCCTGACTAATTTTTG TATTTTTAGTAGAGACGGCGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATC CGCCTACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGATCCACCACACCTGGCCCTTGCAATCTT CTACTTTAAGGTTTGCAGAGATAAACCAATAAATCCACACCGTACATCTGCAATATGAATTCAAGAAAG GAAATAGTACCTTCAATACTTAAAAATAGTCTTCCACAAAAAATACTTTATTTCTGATCTATACAAATT TTCAGAAGGTTATTTTCTTTATCATTGCTAAACTGATGACTTACTATGGGATGGGGTCCAGTCCCATGA CCTTGGGGTACAATTGTAAACCTAGAGTTTTATCAACTTTGGTGAACAGTTTTGGCATAATAGTCAATT TCTACTTCTGGAAGTCATCTCATTCCACTGTTGGTATTATATAATTCAAGGAGAATATGATAAAACACT GCCCTCTTGTGGTGCATTGAAAGAAGAGATGAGAAATGATGAAAAGGTTGCCTGAAAAATGGGAGACAG CCTCTTACTTGCCAAGAAAATGAAGGGATTGGACCGAGCTGGAAAACCTCCTTTACCAGATGCTGACTG GCACTGGTGGTTTTTGCTCTCGACAGTATCCACAATAGCTGACGGCTGGGTGTTTCAGTTTGAAAATAT TTTGTTGCCTTCATCTTCACTGCAATTTTGTGTAAATTTCTCAAAGATCTGAATTAAATAAATAAAATT CATTTCTACAGACCCACA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000903.3
Synonyms	DHQU; DIA4; DTD; NMOR1; NMORI; QR1
Summary	This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Locus ID	1728
MW	61.4

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