SAV1 (NM_021818) Human 3' UTR Clone

Specifications

Product Data
Product Name	SAV1 (NM_021818) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	SAV; WW45; WWP4
ACCN	NM_021818
Insert Size	1633 bp
Sequence Data	Insert Sequence (showhide) >SC215187 3’UTR clone of NM_021818 The sequence shown below is from the reference sequence of NM_021818. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TATGCCCAACAACATGGAAAAAATTTTTGAGCTGATTTTTTAAAAATTTAAGTTTTGTAAGAGCTTTAA AATATTTTCACAGATAAAAAATTGCAAACAAGTACTCTGGTTAATAAATGCTGCTTCCTTTGTGGAAAT TATAAAATTCTAACTTTACATGTATTTTGTTATTAGAAATTTTCTTTTATTGAATGAGAAAAATTAGTC TATCATTTTAAGAGCCAATATGGCAAACACTTTCAAATACTGTATATTAGGAAACTGTTTTGGTATTCT TGATGGAAAAAAACGCAGCGGAAATGTCATTATGAACAGATGTTAAATAGGAAATTATTACTTGTTAAC TTCTTACAGCAGTAGTACCTTCTTTAAAAAAAAAAAAGAATCTGCGGTATTTTTTTAAAAAAAAAGTTT ACCGCTGTAGTGTGAAATATTGTCTGGAAAGGGATGGTTTAAATATTACCATGATGTAGTTGAAATATA AAATAGGATTTGGAACCTTATTGTGATAAATATTTATATATGATGTATGTTTGTCTCCCCTCTCCAAAG TAAGGAACCCAGCTGGGCGTGGTGGCTCACTCCTGTAATCCCAGCATTTTGGGAGGCCGAGGTGGGTGG ACCGCTTGAGTCCACGAGTTTAAGACCAGCCTGGGCAACATGGTGAAGCCCCATCTCTACAAAAAATAC AAAAAAATTAGCCGGGTATGATGGTGTGTGCCTCTAGTCCCAGCTACTTGGGAGGCTGAGGTCAGAGGA TGGCTTGAGCCCAAGAGGCAGAGGTTGCAGGGTCAAGATCGCACCACTTGCACTGCAGCCTGAGAGAGA GAGAGCCAGACCTTGTCTCAAAAAATAAAAAATAAAAAAATAAAAACAAAATAAGGAATCCTTTTAAAG CATGTTGAGAAAGTATTTTTTGGTATGAATGGGTGACGGGCCTTTTAATCTTTCAGGAATACATATAAG CAGGAATACTTAGCCTGTATTGGGAAGGTGCGTGAAACTCAAAGTTGCTAACATCATCTTCCTTATTTT CAGCCAGTGCTGTTACTGCATTTAGCATGGCTCTGACGAGGCAGTGGAGAGTTCCTGACAGCATAGCAT ACTGCCTTCTGACAGACTGGGTTAAGCTACCAAAAATGACAACCAGGGATTCAAAAAAAATTTTTGGTC ATTAAATCGAATGTATATTATTACTTTTTAATTTTCTAAGTATTTATCACAGGACTTTAACACCATATA TTTCCCTCCCAGTTTTTCTCCCCTTTTGGTTTAATAGTTAAAACATTTTTCATAATTAGTGCTGTACAT TTGATTGCAAACAAATTGGTGATACTTCTAAACTATAACTATAAATCTCTAGAATTCTGTGAATTTCAA CATTATTTGAAGTAGTTCTTCAGTTATATTTACATGTGTTGTAAATATGTAAATATACTTTTAGCTTAG GAAGTCTTCCAGAATACAAACTACTCCCAGTTAGATATCAGTGAGTTTGAATAACTGAAGAAATGTTGA CAATGTTAAGTGTTTGATTTTATATAACAAGCTTATTAAATATATTTTTGTGGAAACTAAGCGCGTGGT TTTTGAGTCCATGTTTTAGACATAGTGCTGTATTTCATTTTTCTGT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_021818.4
Synonyms	SAV; WW45; WWP4
Summary	WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. [provided by RefSeq, Aug 2012]
Locus ID	60485
MW	64.2

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