Semaphorin 4D (SEMA4D) (NM_006378) Human 3' UTR Clone

Specifications

Product Data
Product Name	Semaphorin 4D (SEMA4D) (NM_006378) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	A8; BB18; C9orf164; CD100; coll-4; COLL4; GR3; M-sema-G; SEMAJ
ACCN	NM_006378
Insert Size	1499 bp
Sequence Data	Insert Sequence (showhide) >SC214821 3’UTR clone of NM_006378 The sequence shown below is from the reference sequence of NM_006378. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TTCGCTGACTCAGACGCAGATGGAGACTGAGGCCGGCTGTGCATCCCCGCTGGTGCCTCGGCTGCGACG TGTCCAGGCGTGGAGAGTTTTGTGTTTCTCCTGTTCAGTATCCGAGTCTCGTGCAGTGCTGCGTAGGTT AGCCCGCATCGTGCAGACAACCTCAGTCCTCTTGTCTATTTTCTCTTGGGTTGAGCCTGTGACTTGGTT TCTCTTTGTCCTTTTGGAAAAATGACAAGCATTGCATCCCAGTCTTGTGTTCCGAAGTCAGTCGGAGTA CTTGAAGAAGGCCCACGGGCGGCACGGAGTTCCTGAGCCCTTTCTGTAGTGGGGGAAAGGTGGCTGGAC CTCTGTTGGCTGAGAAGAGCATCCCTTCAGCTTCCCCTCCCCGTAGCAGCCACTAAAAGATTATTTAAT TCCAGATTGGAAATGACATTTTAGTTTATCAGATTGGTAACTTATCGCCTGTTGTCCAGATTGGCACGA ACCTTTTCTTCCACTTAATTATTTTTTTAGGATTTTGCTTTGATTGTGTTTATGTCATGGGTCATTTTT TTTTAGTTACAGAAGCAGTTGTGTTAATATTTAGAAGAAGATGTATATCTTCCAGATTTTGTTATATAT TTGGCATAAAATACGGCTTACGTTGCTTAAGATTCTCAGGGATAAACTTCCTTTTGCTAAATGCATTCT TTCTGCTTTTAGAAATGTAGACATAAACACTCCCCGGAGCCCACTCACCTTTTTTCTTTTTCTTTTTTT TTTTTTAACTTTATTCCTTGAGGGAAGCATTGTTTTTGGAGAGATTTTCTTTCTGTACTTCGTTTTACT TTTCTTTTTTTTTAACTTTTACTCTCTCGAAGAAGAGGACCTTCCCACATCCACGAGGTGGGTTTTGAG CAAGGGAAGGTAGCCTGGATGAGCTGAGTGGAGCCAGGCTGGCCCAGAGCTGAGATGGGAGTGCGGTAC AATCTGGAGCCCACAGCTGTCGGTCAGAACCTCCTGTGAGACAGATGGAACCTTCACAAGGGCGCCTTT GGTTCTCTGAACATCTCCTTTCTCTTCTTGCTTCAATTGCTTACCCACTGCCTGCCCAGACTTTCTATC CAGCCTCACTGAGCTGCCCACTACTGGAAGGGAACTGGGCCTCGGTGGCCGGGGCCGCGAGCTGTGACC ACAGCACCCTCAAGCATACGGCGCTGTTCCTGCCACTGTCCTGAAGATGTGAATGGGTGGTACGATTTC AACACTGGTTAATTTCACACTCCATCTCCCCGCTTTGTAAATACCCATCGGGAAGAGACTTTTTTTCCA TGGTGAAGAGCAATAAACTCTGGATGTTTGTGCGCGTGTGTGGACAGTCTTATCTTCCAGCATGATAGG ATTTGACCATTTTGGTGTAAACATTTGTGTTTTATAAGATTTACCTTGTTTTTATTTTTCTACTTTGAA TTGTATACATTTGGAAAGTACCCAAATAAATGAGAAGCTTCTATCCTTGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006378.4
Synonyms	A8; BB18; C9orf164; CD100; coll-4; COLL4; GR3; M-sema-G; SEMAJ
Summary	Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling (PubMed:20877282). Regulates GABAergic synapse development (By similarity). Promotes the development of inhibitory synapses in a PLXNB1-dependent manner (By similarity). Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA (PubMed:19788569). Promotes the migration of cerebellar granule cells (PubMed:16055703). Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro) (PubMed:8876214). Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway (PubMed:16055703).[UniProtKB/Swiss-Prot Function]
Locus ID	10507
MW	57.2

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