CD4 (NM_000616) Human 3' UTR Clone

Specifications

Product Data
Product Name	CD4 (NM_000616) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CD4mut; IMD79; OKT4D
ACCN	NM_000616
Insert Size	1500 bp
Sequence Data	Insert Sequence (showhide) >SC214820 3’UTR clone of NM_000616 The sequence shown below is from the reference sequence of NM_000616. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CGGTTTCAGAAGACATGTAGCCCCATTTGAGGCACGAGGCCAGGCAGATCCCACTTGCAGCCTCCCCAG GTGTCTGCCCCGCGTTTCCTGCCTGCGGACCAGATGAATGTAGCAGATCCCCAGCCTCTGGCCTCCTGT TCGCCTCCTCTACAATTTGCCATTGTTTCTCCTGGGTTAGGCCCCGGCTTCACTGGTTGAGTGTTGCTC TCTAGTTTCCAGAGGCTTAATCACACCGTCCTCCACGCCATTTCCTTTTCCTTCAAGCCTAGCCCTTCT CTCATTATTTCTCTCTGACCCTCTCCCCACTGCTCATTTGGATCCCAGGGGAGTGTTCAGGGCCAGCCC TGGCTGGCATGGAGGGTGAGGCTGGGTGTCTGGAAGCATGGAGCATGGGACTGTTCTTTTACAAGACAG GACCCTGGGACCACAGAGGGCAGGAACTTGCACAAAATCACACAGCCAAGCCAGTCAAGGATGGATGCA GATCCAGAGGTTTCTGGCAGCCAGTACCTCCTGCCCCATGCTGCCCGCTTCTCACCCTATGTGGGTGGG ACCACAGACTCACATCCTGACCTTGCACAAACAGCCCCTCTGGACACAGCCCCATGTACACGGCCTCAA GGGATGTCTCACATCCTCTGTCTATTTGAGACTTAGAAAAATCCTACAAGGCTGGCAGTGACAGAACTA AGATGATCATCTCCAGTTTATAGACCAGAACCAGAGCTCAGAGAGGCTAGATGATTGATTACCAAGTGC CGGACTAGCAAGTGCTGGAGTCGGGACTAACCCAGGTCCCTTGTCCCAAGTTCCACTGCTGCCTCTTGA ATGCAGGGACAAATGCCACACGGCTCTCACCAGTGGCTAGTGGTGGGTACTCAATGTGTACTTTTGGGT TCACAGAAGCACAGCACCCATGGGAAGGGTCCATCTCAGAGAATTTACGAGCAGGGATGAAGGCCTCCC TGTCTAAAATCCCTCCTTCATCCCCCGCTGGTGGCAGAATCTGTTACCAGAGGACAAAGCCTTTGGCTC TTCTAATCAGAGCGCAAGCTGGGAGCACAGGCACTGCAGGAGAGAATGCCCAGTGACCAGTCACTGACC CTGTGCAGAACCTCCTGGAAGCGAGCTTTGCTGGGAGAGGGGGTAGCTAGCCTGAGAGGGAACCCTCTA AGGGACCTCAAAGGTGATTGTGCCAGGCTCTGCGCCTGCCCCACACCCTCCCTTACCCTCCTCCAGACC ATTCAGGACACAGGGAAATCAGGGTTACAAATCTTCTTGATCCACTTCTCTCAGGATCCCCTCTCTTCC TACCCTTCCTCACCACTTCCCTCAGTCCCAACTCCTTTTCCCTATTTCCTTCTCCTCCTGTCTTTAAAG CCTGCCTCTTCCAGGAAGACCCCCCTATTGCTGCTGGGGCTCCCCATTTGCTTACTTTGCATTTGTGCC CACTCTCCACCCCTGCTCCCCTGAGCTGAAATAAAAATACAATAAACTTAC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000616.5
Synonyms	CD4mut; IMD79; OKT4D
Summary	This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
Locus ID	920
MW	54.7

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