IGF2R (NM_000876) Human 3' UTR Clone

Specifications

Product Data
Product Name	IGF2R (NM_000876) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R; MPR1; MPR 300; MPR300; MPRI
ACCN	NM_000876
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC214752 3’UTR clone of NM_000876 The sequence shown below is from the reference sequence of NM_000876. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GACAGCGACGAGGACCTCTTACACATCTGACTCCGCAGTGCCTGCAGGGGAGCACGGAGCCGCGGGACA GCCAAGCACCTCCAACCAAATAAGACTTCCACTCGATGATGCTTCTATAATTTTGCCTTTAACAGAAAC TTTCAAAAGGGAAGAGTTTTTGTGATGGGGGAGAGGGTGAAGGAGGTCAGGCCCCACTCCTTCCTGATT GTTTACAGTCATTGGAATAAGGCATGGCTCAGATCGGCCACAGGGCGGTACCTTGTGCCCAGGGTTTTG CCCCAAGTCCTCATTTAAAAGCATAAGGCCGGACGCATCTCAAAACAGAGGGCTGCATTCGAAGAAACC CTTGCTGCTTTAGTCCCGATAGGGTATTTGACCCCGATATATTTTAGCATTTTAATTCTCTCCCCCTAT TTATTGACTTTGACAATTACTCAGGTTTGAGAAAAAGGAAAAAAAAACAGCCACCGTTTCTTCCTGCCA GCAGGGGTGTGATGTACCAGTTTGTCCATCTTGAGATGGTGAGGCTGTCAGTGTATGGGGCAGCTTCCG GCGGGATGTTGAACTGGTCATTAATGTGTCCCCTGAGTTGGAGCTCATTCTGTCTCTTTTCTCTTTTGC TTTCTGTTTCTTAAGGGCACACACACGTGCGTGCGAGCACACACACACATACGTGCACAGGGTCCCCGA GTGCCTAGGTTTTGGAGAGTTTGCCTGTTCTATGCCTTTAGTCAGGAATGGCTGCACCTTTTTGCATGA TATCTTCAAGCCTGGGCGTACAGAGCACATTTGTCAGTATTTTTGCCGGCTGGTGAATTCAAACAACCT GCCCAAAGATTGATTTGTGTGTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGAGTGGAGTTGAG GTGTCAGAGAAAATGAATTTTTTCCAGATTTGGGGTATAGGTCTCATCTCTTCAGGTTCTCATGATACC ACCTTTACTGTGCTTATTTTTTTAAGAAAAAAGTGTTGATCAACCATTCGACCTATAAGAAGCCTTAAT TTGCACAGTGTGTGACTTACAGAAACTGCATGAAAAATCATGGGCCAGAGCCTCGGCCCTAGCATTGCA CTTGGCCTCATGCTGGAGGGAGGCTGGGCGGGTACAGCGCGGAGGAGGAGGGAGGCCAGGCGGGCATGG CGTGGAGGAGGAGGGAGGCCGGGCGGTCACAGCATGGAGGAGGAGGGAGGCGCTGCTGGTGTTCTTATT CTGGCGGCAGCGCCTTTCCTGCCATGTTTAGTGAATGACTTTTCTCGCATTGTAGAATTGTATATAGAC TCTGGTGTTCTATTGCTGAGAAGCAAACCGCCCTGCAGCATCCCTCAGCCTGTACCGGTTTGGCTGGCT TGTTTGATTTCAACATGAGTGTATTTTTTAAAATTGATTTTTCTCTTCATTTTTTTTTCAATCAACTTT ACTGTAATATAAAGTATTCAACAATTTCAATAAAAGATAAATTATTAATTGGGTGTTACCATTTTTTCC TTGATAGTGAGACGTTCCCGAGCGAGTTACCCATCTGCCTGCCTGTCTTTTCTTTCTGTTAAGTGACTG AATTTGGGTTTTAACTCTGGTGTTCTCGTTGACCCTTTATGAGGCAGCACTTTCATTTTTCTCCAGAGT CTCCTGGTCGTAGGTGTTAACTTTGGGTCCAATCTGCCTTCCCTTGGCTCTTTCTAGATCCGATTTCTT TACCTTCTCCAGGCCAACCTCGGGGTGTGGTCCTGTTCATCAAAACAATGAACATGGAGTTTAGAGTCC AGTGAGTCAATAAAGCTTTTTTTTGTGCAACCTGATCTAACATGGAGATGTTTTCTCTTGAGTAAACTC ACTGAGTTTTCCATCTTAAATTACTCAGCAGTGACTGAGAGCTACCTGCATGGAAGCAGGAAGTTACTC CAGTGTTATAAACAAACTTCTTAGACTCAACATCCTATTCTCCATCCCTTTTTTTTTCCTGTAGAGTC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000876.4
Synonyms	CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R; MPR1; MPR 300; MPR300; MPRI
Summary	This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015]
Locus ID	3482
MW	74.9

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