TJP1 (NM_175610) Human 3' UTR Clone

Specifications

Product Data
Product Name	TJP1 (NM_175610) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ZO-1
ACCN	NM_175610
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC214629 3’UTR clone of NM_175610 The sequence shown below is from the reference sequence of NM_175610. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TGTGTTTCTGTCCTTATTGACCACTTTTAACTCTTGAAATATAGGAACTTAAATAATGTGAAACTGGAT TAAACTTAATCTAAATGGAACCACTCTATCAAGTATTATACCTTTTTTAGAGTTGATACTACAGTTTGT TAGTATGAGGCATTTGTTTGAACTGATAAAGATGAGTGAGCATGCCCCTGAACCATGGTCGGAAAACAT GCTACACACTGCATGTTTGTGATTGACGGGACTGTTGGTATTGGCTAGAGGTTCAAAGATATTTTGCTT TGTGATTTTTGTAATTTTTTTATCGTCACTGCTTAACTTCACATATTGATTTCCGTTAAAATACCAGCC AGTAAATGGGGGTGCATTTGAGGTCTGTTCTTTCCAAAGTACACTGTTTCAAACTTTACTATGGCCCTG GCCTAGCATACGTACACATTTTATTTTATTATGCATGAAGTAATATGCACACATTTTTTAAATGCACCT GGAATATATAACCAGTGTTGTGGATTTAACAGAAATGTACAGCAAGGAGATTTACAACTGGGGGAGGGT GAAGTGAAGACAATGACTTACTGTACATGAAAACACATTTTTCTTAGGGAAGGATACAAAAGCATGTGA GACTGGTTCCATGGCCTCTTCAGATCTCTAACTTCACCATATTACCACAGACATACTAACCAGCAGAAA TGCCTTACCCTCATGTTCTTAATTCTTAGCTCATTCTCCTTGTGTTACTAAGTTTTTATGGCTTTTGTG CATTATCTAGATACTGTATCATGACAAAGACTGAGTACGTTGTGCATTTGGTGGTTTCAGAAATGTGTT ATCACCCAGAAGAAAATAGTGGTGTGATTTGGGGATATTTTTTTCTTTTCTTTTCTTTTCTTTTTTTTT TTTTTTGACAAGGGGCAGTGGTGGTTTTCTGTTCTTTCTGGCTATGCATTTGAAAATTTTGATGTTTTA AGGATGCTTGTACATAATGCGTGCATACCACTTTTGTTCTTGGTTTGTAAATTAACTTTTATAAACTTT ACCTTTTTTATACATAAACAAGACCACGTTTCTAAAGGCTACCTTTGTATTCTCTCCTGTACCTCTTGA GCCTTGAACTTTGACCTCTGCAGCAATAAAGCAGCGTTTCTATGACACATGCAAGGTCATTTTTTTTAA GAAAAAGGATGCACAGAGTTGTTACATTTTTAAGTGCTGCATTTAAAAGATACAGTTACTCAGAATTCT CTAGTTTGATTAAATTCTTGCAAAGTATCCCTACTGTAATTTGTGATACAATGCTGTGCCCTAAAGTGT ATTTTTTTACTAATAGACAATTTATTATGGCACATCAGCACGATTTCTGTTTAGATAATACACCACTAC ATTCTGTTAATCATTAGGTGTGACTGAATTTCTTTTGCCGTTATTAAAAATCTCAAATTTCTAAATCTC CAAAATAAAACTTTTTAAAATAAAGTGCTGGCTTGGTCTGTTTGCCCACTGTTTTCTAGTTTCATGCAG CTTTATAATCCTGTTTTAAAATCCTGCACACAAATCCCTATCACCCAGCGTCACCTACCACCTCGTCGT CTGGTGTTGCATGCAGAATTTCTCCCCTTGGCCAGCATGTACAGATGGGTGGGCAGTGCTCATCTGAAG GGCTCAGACTGAAGTGGGGCAGAAGGACCTGGAGACAGAGTGGGAGAAGGCAGCAGGCCGACTTCCCCC TGTGGGTAAACACACACCCCTGCGTGGAGAAACACCCCTGCATGGGGACACACGTGCGTTTGTGTGTGT GCGTGTAACCATTTGTATATGGTTTTATTCCCCAGATAAATAGCACGGGCATTGTTTAATGTCACCCAC ATTTGGGGGAAGAAAATGGGTTTAGTGAGCATAAATATTCCATTGTGGACATCCTACTTACTTAACTGC CACCCCTGTTGACATTTGGATTATTGCTATAGTGTTTCAGTAAACACCTTTGTGGACTGAATCCATCT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_175610.4
Synonyms	ZO-1
Summary	This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules between endothelial and epithelial cells. The multidomain structure of this scaffold protein, including a postsynaptic density 95/disc-large/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]
Locus ID	7082
MW	77

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