CD8A (NM_001145873) Human 3' UTR Clone

Specifications

Product Data
Product Name	CD8A (NM_001145873) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CD8; Leu2; p32
ACCN	NM_001145873
Insert Size	1468 bp
Sequence Data	Insert Sequence (showhide) >SC214603 3’UTR clone of NM_001145873 The sequence shown below is from the reference sequence of NM_001145873. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAGCCCAGCCTTTCGGCGAGATACGTCTAACCCTGTGCAACAGCCACTACATTACTTCAAACTGAGATC CTTCCTTTTGAGGGAGCAAGTCCTTCCCTTTCATTTTTTCCAGTCTTCCTCCCTGTGTATTCATTCTCA TGATTATTATTTTAGTGGGGGCGGGGTGGGAAAGATTACTTTTTCTTTATGTGTTTGACGGGAAACAAA ACTAGGTAAAATCTACAGTACACCACAAGGGTCACAATACTGTTGTGCGCACATCGCGGTAGGGCGTGG AAAGGGGCAGGCCAGAGCTACCCGCAGAGTTCTCAGAATCATGCTGAGAGAGCTGGAGGCACCCATGCC ATCTCAACCTCTTCCCCGCCCGTTTTACAAAGGGGGAGGCTAAAGCCCAGAGACAGCTTGATCAAAGGC ACACAGCAAGTCAGGGTTGGAGCAGTAGCTGGAGGGACCTTGTCTCCCAGCTCAGGGCTCTTTCCTCCA CACCATTCAGGTCTTTCTTTCCGAGGCCCCTGTCTCAGGGTGAGGTGCTTGAGTCTCCAACGGCAAGGG AACAAGTACTTCTTGATACCTGGGATACTGTGCCCAGAGCCTCGAGGAGGTAATGAATTAAAGAAGAGA ACTGCCTTTGGCAGAGTTCTATAATGTAAACAATATCAGACTTTTTTTTTTTATAATCAAGCCTAAAAT TGTATAGACCTAAAATAAAATGAAGTGGTGAGCTTAACCCTGGAAAATGAATCCCTCTATCTCTAAAGA AAATCTCTGTGAAACCCCTATGTGGAGGCGGAATTGCTCTCCCAGCCCTTGCATTGCAGAGGGGCCCAT GAAAGAGGACAGGCTACCCCTTTACAAATAGAATTTGAGCATCAGTGAGGTTAAACTAAGGCCCTCTTG AATCTCTGAATTTGAGATACAAACATGTTCCTGGGATCACTGATGACTTTTTATACTTTGTAAAGACAA TTGTTGGAGAGCCCCTCACACAGCCCTGGCCTCTGCTCAACTAGCAGATACAGGGATGAGGCAGACCTG ACTCTCTTAAGGAGGCTGAGAGCCCAAACTGCTGTCCCAAACATGCACTTCCTTGCTTAAGGTATGGTA CAAGCAATGCCTGCCCATTGGAGAGAAAAAACTTAAGTAGATAAGGAAATAAGAACCACTCATAATTCT TCACCTTAGGAATAATCTCCTGTTAATATGGTGTACATTCTTCCTGATTATTTTCTACACATACATGTA AAATATGTCTTTCTTTTTTAAATAGGGTTGTACTATGCTGTTATGAGTGGCTTTAATGAATAAACATTT GTAGCATCCTCTTTAATGGGTAAACAGCATCCGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001145873.1
Synonyms	CD8; Leu2; p32
Summary	The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
Locus ID	925
MW	55.7

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