PRKACA (NM_207518) Human 3' UTR Clone

CAT#: SC214564

3' UTR clone of protein kinase cAMP-dependent catalytic alpha (PRKACA) transcript variant 2 for miRNA target validation



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CNY 4,845.00


货期*
3周

规格
    • 10 ug

Product images

经常一起买 (2)
Firefly luciferase assay kit, 150 assays
    • 1 kit

CNY 1,520.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00

Specifications

Product Data
Product Name PRKACA (NM_207518) Human 3' UTR Clone
Vector pMirTarget
Synonyms CAFD1; PKACA; PPNAD4
ACCN NM_207518
Insert Size 1454 bp
Sequence Data
>SC214564 3’UTR clone of NM_207518
The sequence shown below is from the reference sequence of NM_207518. The complete sequence of this clone may contain minor differences, such as SNPs.
Blue=Stop Codon Red=Cloning site

GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
AAGTGTGGCAAGGAGTTTTCTGAGTTTTAGGGGCATGCCTGTGCCCCCATGGGTTTTCTTTTTTCTTTT
TTCTTTTTTTTGGTCGGGGGGGTGGGAGGGTTGGATTGAACAGCCAGAGGGCCCCAGAGTTCCTTGCAT
CTAATTTCACCCCCACCCCACCCTCCAGGGTTAGGGGGAGCAGGAAGCCCAGATAATCAGAGGGACAGA
AACACCAGCTGCTCCCCCTCATCCCCTTCACCCTCCTGCCCCCTCTCCCACTTTTCCCTTCCTCTTTCC
CCACAGCCCCCCAGCCCCTCAGCCCTCCCAGCCCACTTCTGCCTGTTTTAAACGAGTTTCTCAACTCCA
GTCAGACCAGGTCTTGCTGGTGTATCCAGGGACAGGGTATGGAAAGAGGGGCTCACGCTTAACTCCAGC
CCCCACCCACACCCCCATCCCACCCAACCACAGGCCCCACTTGCTAAGGGCAAATGAACGAAGCGCCAA
CCTTCCTTTCGGAGTAATCCTGCCTGGGAAGGAGAGATTTTTAGTGACATGTTCAGTGGGTTGCTTGCT
AGAATTTTTTTAAAAAAACAACAATTTAAAATCTTATTTAAGTTCCACCAGTGCCTCCCTCCCTCCTTC
CTCTACTCCCACCCCTCCCATGTCCCCCCATTCCTCAAATCCATTTTAAAGAGAAGCAGACTGACTTTG
GAAAGGGAGGCGCTGGGGTTTGAACCTCCCCGCTGCTAATCTCCCCTGGGCCCCTCCCCGGGGAATCCT
CTCTGCCAATCCTGCGAGGGTCTAGGCCCCTTTAGGAAGCCTCCGCTCTCTTTTTCCCCAACAGACCTG
TCTTCACCCTTGGGCTTTGAAAGCCAGACAAAGCAGCTGCCCCTCTCCCTGCCAAAGAGGAGTCATCCC
CCAAAAAGACAGAGGGGGAGCCCCAAGCCCAAGTCTTTCCTCCCAGCAGCGTTTCCCCCCAACTCCTTA
ATTTTATTCTCCGCTAGATTTTAACGTCCAGCCTTCCCTCAGCTGAGTGGGGAGGGCATCCCTGCAAAA
GGGAACAGAAGAGGCCAAGTCCCCCCAAGCCACGGCCCGGGGTTCAAGGCTAGAGCTGCTGGGGAGGGG
CTGCCTGTTTTACTCACCCACCAGCTTCCGCCTCCCCCATCCTGGGCGCCCCTCCTCCAGCTTAGCTGT
CAGCTGTCCATCACCTCTCCCCCACTTTCTCATTTGTGCTTTTTTCTCTCGTAATAGAAAAGTGGGGAG
CCGCTGGGGAGCCACCCCATTCATCCCCGTATTTCCCCCTCTCATAACTTCTCCCCATCCCAGGAGGAG
TTCTCAGGCCTGGGGTGGGGCCCCGGGTGGGTGCGGGGGCGATTCAACCTGTGTGCTGCGAAGGACGAG
ACTTCCTCTTGAACAGTGTGCTGTTGTAAACATATTTGAAAACTATTACCAATAAAGTTTTGTTTAAAA
AAAAA
ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites SgfI-MluI     
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq NM_207518.3
Synonyms CAFD1; PKACA; PPNAD4
Summary This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. Tissue-specific isoforms that differ at the N-terminus have been described, and these isoforms may differ in the post-translational modifications that occur at the N-terminus of some isoforms. [provided by RefSeq, Jan 2015]
Locus ID 5566
MW 52.6
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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