GCLC (NM_001498) Human 3' UTR Clone

Specifications

Product Data
Product Name	GCLC (NM_001498) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	GCL; GCS; GLCL; GLCLC
ACCN	NM_001498
Insert Size	1445 bp
Sequence Data	Insert Sequence (showhide) >SC214464 3’UTR clone of NM_001498 The sequence shown below is from the reference sequence of NM_001498. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGTGGAAGTAAAACTGACTCATCCAACTAGACATTCTACAGAAAGAAAAATGCATTATTGACGAACTGG CTACAGTACCATGCCTCTCAGCCAGCCCGTGTGTATAATATGAAGACCAAATGATAGAACTGTACTGTT TTCTGGGCCAGTGAGCCAGAAATTGATTAAGGCTTTCTTTGGTAGGTAAATCTAGAGTTTATACAGTGT ACATGTACATAGTAAAGTATTTTTGATTAACAATGTATTTTAATAACATATCTAAAGTCATCATGAACT GGCTTGTACATTTTTAAATTCTTACTCTGGAGCAACCTACTGTCTAAGCAGTTTTGTAAATGTACTGGT AATTGTACAATACTTGCATTCCAGAGTTAAAATGTTTACTGTAAATTTTTGTTCTTTTAAAGACTACCT GGGACCTGATTTATTGAAATTTTTCTCTTTAAAAACATTTTCTCTCGTTAATTTTCCTTTGTCATTTCC TTTGTTGTCTACATTAAATCACTTGAATCCATTGAAAGTGCTTCAAGGGTAATCTTGGGTTTCTAGCAC CTTATCTATGATGTTTCTTTTGCAATTGGAATAATCACTTGGTCACCTTGCCCCAAGCTTTCCCCTCTG AATAAATACCCATTGAACTCTGATGGCTGTTATCAAAGGAACTTTTCTTTGTTTAAATTTGCTGATGCA GGAATTAAGTTTAAACACAACTCTATAGAAAGAAAGGAGATTATTACCCAGAATTCACATGTAGTGATT ATTAAGGACAATTTTTTTTTTTAACTAAAAAAGTTGGCGGCAGGGGTGGGGGGTGGCAATCATTTTTCT TCCTATACATACAAAGGATATTGTCAAAAATGGCGTTCTTCTCTTGTGGCCTGTTATTCTGATTGCTGC TGTATACAGTTTTGTCACTCTTTAGTTTTTAGTTAAGCATACTGATAGACTTTCCTCTAAAAGCCATTC ACTCCAGATTTTACCTGGGGAATATTCTACATACTGCTTACTTTCTCTATAAAACTCATCAATAAATCA TGAAAGGCACTGAGTTTTGTAAATCAGGACCCTAAATGTTTAATTGTAAATAAGTTTCAGATAATTATT ATAGCTTTGCGTTGAAGTTTGTTGTTTTTTTTCTCAACTAGTTAAGTCAACTGCTTCTGAAATAACTCT GTATTGTAGATTATGCAGATCTTTACAGGCATAAATATTTAAACTGTAATATGCTAACTTGAAGAGATT GCAATAAAGCTGCTTCAGCTAACCCTGTTTATGTTTAAATACTAGGGTTTGTTCTATATTTTATACATG CATTTTGGATGATTAAAGAATGCCTGGTTTTCGTTTGCAATTTGCTTGTGTAAATCAGGTTGTAAAAAG GCAGATAAATTGAAATGTTTGTGGTATGAGGAAATAAAAGAATGGAATTAGCTTTCATTCAGAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001498.4
Synonyms	GCL; GCS; GLCL; GLCLC
Summary	Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010]
Locus ID	2729
MW	55.8

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