Optineurin (OPTN) (NM_021980) Human 3' UTR Clone

CAT#: SC214448

3' UTR clone of optineurin (OPTN) transcript variant 2 for miRNA target validation



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CNY 4,845.00


货期*
3周

规格
    • 10 ug

Product images

经常一起买 (2)
Firefly luciferase assay kit, 150 assays
    • 1 kit

CNY 1,520.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00

Specifications

Product Data
Product Name Optineurin (OPTN) (NM_021980) Human 3' UTR Clone
Vector pMirTarget
Synonyms ALS12; FIP2; GLC1E; HIP7; HYPL; NRP; TFIIIA-INTP
ACCN NM_021980
Insert Size 1440 bp
Sequence Data
>SC214448 3’UTR clone of NM_021980
The sequence shown below is from the reference sequence of NM_021980. The complete sequence of this clone may contain minor differences, such as SNPs.
Blue=Stop Codon Red=Cloning site

GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
CAGATTCACGTGATGGATTGCATCATTTAAGTGTTGATGTATCACCTCCCCAAAACTGTTGGTAAATGT
CAGATTTTTTCCTCCAAGAGTTGTGCTTTTGTGTTATTTGTTTTCACTCAAATATTTTGCCTCATTATT
CTTGTTTTAAAAGAAAGAAAACAGGCCGGGCACAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGG
TCGAGGTGGGTGGATCACTTGGGGTCAGGGTTTGAGACCAGCCTGGCCAACATGGCGGAACCCTGTCTC
TACCAAAATTACAAAAATTAGCCGAGCATGGTGGCGCATGCCTGTAGTCGCAGCTACTCGCGAGGTTGA
GGCAGGAGAATTGCTTGAACCCAGGAAGTGGCAGTTGCAGTGAGCCGAGACGACACCACTGCACTCCAG
CCTGGGTGACAGAGGGAGACTCTGTCTCGAAAGAAAGAAAGAAAAAAAGGAAGGAAGGAGAAGGAAGGA
AGGAGAAGAAAAGGTACCTGTTCTACGTAGAACACCTTTGGTGGAGTTCCATCAACTCGCAAAGTAGAA
TCCTTACCTACTACTCTTCTGATAATAATTTTAATATTTTTTATGTTTGGTTGATGCGAGCAGCTGCAC
TGCTCATGCAGTTAGCTAGCATGTGACATCATGTGACAAAGTTCATGTAATTAGATGGAAGAAACCTCA
CTGATTAATTTTAAGAACCTTTTAGGGATGCAGGAACAATGAAGTGGCCACAGTATGTGCTGTTTTTGA
AGCATTTTTAAAAACGAATTGTAGTTGTTTTTCTTCATTTAAAATGGATCTGTTGGAGGTTATGTGTGT
ATGTTGTAGTTTTATTGCAGCCACAATAATTTTACCAAAGTTTTCACATAGGCAGTTAGCCTTTACTTA
ATATCAAGACAAGTGAAAAAATATTGGCATCGATGAAACCGATAACATTGGCCTCATTGGATTTCTTTA
CCCATTCACAGTGTAAAGAAGTTACCTTCATGCTTTCATTGTACCTGCAGGCCTGTGGGCTTGTACAGT
AGATAATTAATTTCTAAAAAGAACAGCTGCCTATTTTCTTCCTAGGTTAGGTTATATCTTCATAATCAC
AAGAATTAGTGATGGCAAAATAAAATTTTGCTTATGAATCTTTTACATTGTTTATATATGATTAATATC
ATCATATATATTTTCTGTATTAAGCTCATTTGGCTTCATTTAAGCTGTATACTTAGTCATATATCTTTC
ATTAGTTCTATGGATATGAGCAGATCCCTTTACTGGAGCCCAGTATGTGCTGTGTGAGTTAGAAGTCAT
TCTTGCTGAGAAGGTGAATAGGTAGGGATTTGCCTTGTTTTGTAAGTCTACAATTTGCCAAGAGTAAAT
AACACTGGACCAGCTGTAAAAGTAAACAGTGTGTTTATGCATTGAGATACTAAAGCATTT
ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites SgfI-MluI     
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq NM_021980.4
Synonyms ALS12; FIP2; GLC1E; HIP7; HYPL; NRP; TFIIIA-INTP
Summary This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Locus ID 10133
MW 55
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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