USP20 (NM_001110303) Human 3' UTR Clone
CAT#: SC214248
3' UTR clone of ubiquitin specific peptidase 20 (USP20) transcript variant 3 for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
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经常一起买 (2)
Specifications
Product Data | |
Product Name | USP20 (NM_001110303) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | hVDU2; LSFR3A; VDU2 |
ACCN | NM_001110303 |
Insert Size | 1408 bp |
Sequence Data |
>SC214248 3’UTR clone of NM_001110303
The sequence shown below is from the reference sequence of NM_001110303. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAGATCGAAGCCGAGACGCGGGCCGTGTGATCTGCTGGGCTAGTCTCCCCATGTGCCCCACCCCGCGGA AGGCGTGTTTGTGCCCAGAAGAGAGGCCGGGCTGCTGCAGAACCCCGCCGTGTAAAGAGGCAGAAAAGT TGGTTTGGTTTGCAGTAACGCTGCAACTAGAAAATATATGCACTTCAGGCTTGTTGAAACGACCAAGAC TCTGTGACGTTAATTTGGGTCTTTGTCCTGGCAGTGCCTCTGCCAGTCACTGTCATCGTTGTGTCCCCC ACAACTGTCCTCTTGCTAGCTCGGCCCAGCTTTGTCCCTGGAGCCCGATGCTACCCCTGTCAGACAGAG GCTGCGGCCTGGGCCAGAGTCAGGGAGTAGCTGCTGCTTCACGGCGTCTCCACTGTGCGATTGGCCCGG AGCCCCGAAGACTCGGAGGGAGCTGCTCAGGGCCGGTGAGCGCAGCCAGAAGCCCTGGCCAGTGAGGAG CTCACAGGTCCTCCCTGGTGGTCCCGCCGCACCTCTGCATCTCCTGGGCGTCACCAGGAAGGCTCTGAA GTCCCGGGCTGCTCTCAGCACTTCTCCTGCAGACTGAAGACTCTGGACTCATTGCTGATTGGAACACCA GGAGGAGGTTGGATTTCTGCCAGTGGGGGATGTTTCTGGAGGCAGCTGGTCCCCCACACCGCGTCCTGC TGAGCCTGCCCCCTGGATTGGCTGTAATTTGCCTCGAAGTTCAGCAGTTCATCTTCATGGGAAATTTGC TGAGCCCCCACCAGGGAACCGGATGATGAAACAGGGATACCTCACAGCTTGGCCATTTGAGGCAAAGGC AGCTTCCCGAGCTGATGCTAAAGAAGACAGACTTTCCCTTCCTCCCAGCAGCAGCAGTGCAGAGCCCAC CTGGAGGGATGTGGGGGCTGTGCAGGGTGCAGCGCTCAGGTGGATCCTGGGAAGCAGCCTCTGGATGCT GAGTGGAGGGAGCCACTGAGCACAGCAAGGCACCAAAGCCCCTGGAGAAACCGCCAGGGCGAGGTGCGA CCATCATCAGGATCAAAGCAGACGGGGCGTGGGTGGGGAAGGGGCTCTGGGACCAGACCCCCCACACTA CTGCGTCTTTGTTTCTATCAGTCTTTGTAGAAGCAGGTGGTGGTGGAAATTCCAGCAGGTGGGTCCCGC AGAGGCCCTGAGGCCTCACTTTTCGGATCTTCTGTCCCAGATCCTGCTCCCTCCCTGCTGAGCCTGGGG TTCCCCTGGCATTGGCCCCAGCCTTCTGAAAGCCGGCGCTGCAGCCAGAGGCCGCACGCTGCACTGTCG CGACGCAGAGAGGCTTCTGTGCAGGCTGGGATCGGGCCCCATGTCTGTGCTGTCTAGTTTGTGTTCAAA ATGTCAGAATAAACACAGAATAAATGTT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_001110303.4 |
Synonyms | hVDU2; LSFR3A; VDU2 |
Summary | This gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel-Lindau disease) protein E3 ubiquitin ligase complex. In addition to being ubiquitinated by the VHL-E3 ligase complex, this enzyme deubiquitinates hypoxia-inducible factor (HIF)-1 alpha and thereby causes increased expression of HIF-1alpha targeted genes which play a role in angiogenesis, glucose metabolism, cell proliferation and metastasis. The enzyme encoded by this gene also regulates G-protein coupled receptor signaling by mediating the deubiquitination of beta-2 adrenergic receptor (ADRB2). This enzyme is a ubiquitously expressed thiolester hydrolase. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jan 2013] |
Locus ID | 10868 |
MW | 51 |
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