EP4 (PTGER4) (NM_000958) Human 3' UTR Clone

Specifications

Product Data
Product Name	EP4 (PTGER4) (NM_000958) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	EP4; EP4R
ACCN	NM_000958
Insert Size	1387 bp
Sequence Data	Insert Sequence (showhide) >SC214214 3’UTR clone of NM_000958 The sequence shown below is from the reference sequence of NM_000958. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACACTGAACTTATCAGAAAAATGTATATAATAGGCAAGGAAAGAAATACAGTACTGTTTCTGGACCCTT ATAAAATCCTGTGCAATAGACACATACATGTCACATTTAGCTGTGCTCAGAAGGGCTATCATCATCCTA CAACTCACATTAGAGAACATCCTGGCTTTTGAGCACTTTTCAAACAATCAAGTTGACTCACGTGGGTCC TGAGGCCTGCAGCACGTCGGATGCTACCCCACTATGACAGAGGATTGTGGTCACAACTTGATGGCTGCG AAGACCTACCCTCCGTTTTTCTACTAGATAGGAGGATGGTAGAAGTTTGGCTGCTGTCATAACATCCAG AGCTTTGTCGTATTTGGCACACAGCAGAGGCCCAGATATTAGAAAGGCTCTATTCCAATAAACTATGAG GACTGCCTTATGGATGATTTAAGTGTCTCACTAAAGCATGAAATGTGAATTTTTATTGTTGTACATACG ATTTAAGGTATTTAAAGTATTTTCTTCTCTGTGAGAAGGTTTATTGTTAATACAAGGTATAATAAAATT ATCGCAACCCCTCTCCTTCCAGTATAACCAGCTGAAGTTGCAGATGTTAGATATTTTTCATAAACAAGT TCGAGTCAAAGTTGAAAATTCATAGTAAGATTGATATCTATAAAATAGATATAAATTTTTAAGAGAAAG AATTTAGTATTATCAAAGGGATAAAGAAAAAAATACTATTTAAGATGTGAAAATTACAGTCCAAAATAC TGTTCTTTCCAGGCTATGTATAAAATACATAGTGAAAATTGTTTAGTGATATTACATTTATTTATCCAG AAAACTGTGATTTCAGGAGAACCTAACATGCTGGTGAATATTTTCAACTTTTTCCCTCACTAATTGGTA CTTTTAAAAACATAACATAAATTTTTTGAAGTCTTTAATAAATAACCCATAATTGAAGTGTATAATATA AAAAATTTTAAAAATCTAAGCAGCTTATTGTTTCTCTGAAAGTGTGTGTAGTTTTACTTTCCTAAGGAA TTACCAAGAATATCCTTTAAAATTTAAAAGGATGGCAAGTTGCATCAGAAAGCTTTATTTTGAGATGTA AAAAGATTCCCAAACGTGGTTACATTAGCCATTCATGTATGTCAGAAGTGCAGAATTGGGGCACTTAAT GGTCACCTTGTAACAGTTTTGTGTAACTCCCAGTGATGCTGTACACATATTTGAAGGGTCTTTCTCAAA GAAATATTAAGCATGTTTTGTTGCTCAGTGTTTTTGTGAATTGCTTGGTTGTAATTAAATTCTGAGCCT GATATTGATATGGTTTTAAGAAGCAGTTGTACCAAGTGAAATTATTTTGGAGATTATAATAAATATATA CATTCAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000958.3
Synonyms	EP4; EP4R
Summary	The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]
Locus ID	5734
MW	53.7

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