HSD3B7 (NM_001142778) Human 3' UTR Clone

Specifications

Product Data
Product Name	HSD3B7 (NM_001142778) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CBAS1; PFIC4; SDR11E3
ACCN	NM_001142778
Insert Size	1350 bp
Sequence Data	Insert Sequence (showhide) >SC214048 3’UTR clone of NM_001142778 The sequence shown below is from the reference sequence of NM_001142778. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCCGGGAGCTGGAGCAGCGGGCAACCCTGATGGGCGGCCAGGTATACTTCTGCTACGATGGATCACCCT ACAGGAGCTACGAGGATTTCAACATGGAGTTCCTGGGCCCCTGCGGACTGCGGCTGGTGGGCGCCCGCC CATTGCTGCCCTACTGGCTGCTGGTGTTCCTGGCTGCCCTCAATGCCCTGCTGCAGTGGCTGCTGCGGC CACTGGTGCTCTACGCACCCCTGCTGAACCCCTACACGCTGGCCGTGGCCAACACCACCTTCACCGTCA GCACCGACAAGGCTCAGCGCCATTTCGGCTATGAGCCCCTGTTCTCGTGGGAGGATAGCCGGACCCGTA CCATTCTCTGGGTACAGGCCGCTACGGGTTCAGCCCAGTGACGGTGGGGCTGGGGCCTGGAGGCCCAGA TACAGCACATCCACCCAGGTCCCGAGCCCTCACACCCTGGACGGGAAGGGACAGCTGCATTCCAGAGCA GGAGGCAGGGCTCTGGGGCCAGAATGGCTGTCCTTGTCGTAGAGCCCTCCACATTTTCTTTTTCTTTTT TGAGACAGGGTCTTGCTCTGTCACCCAGACTGGAGTGCAGTGGTGTGATCATAGCTCACTGCACCCTCA ACCTCCTGGGTTCAAGCAATCCTCCTGCCTCAGCCTCCTGAACAGCTGGGACCACAGGTGCACGCCACC ACACCTGGCTTTTTTTTGTTGTTTTTAGAGACAGGGTCTCACTATATTGCTCAGGCTGGTCTTGAACTC CTGGGCTCAAGTGATCTTCCCACGTGGGCCTCCCAAAACGCTGGAACTACAAGTGTGAGCCACCGCGCC TGGCCCAAGCCCTCCACATTTTCAATCCAGGAGCCTTGAGTCTGTGTTGTGTCCTGACACCTCCAAGTT CTAGGGCCGTCAGGACACGGGAGGGTTTGGGGACAGAGTGTCCTTCCTCTGTCCTCTCATCCCAGTCCT GATGGCCGCTTGGTGAGTGTCTGGTGCCCTGGTGGCCTGCCCCAGCTCTCTTCTGGCTTTCTGAGCAGG AAGCGAGCAGAGGCTCCACAGGCTTACGCTGCTCTCCTGACAGCCACACGCGACCCTCGGTGCAGAGTG CAGAGGCGGCTCTGGTTCCTCCAGCCACCTCAGTCCCTCTTTGGGAGGTGATGTTCCCATTGTTTTTCA AAGGCCTCACCTTCAACTGTCTGTCTTAGAATTCCCCTCTGGAGGGCTATGGCCTCCCTATGCTTTCAC TTCCCACCTCTCTACCTAAGTTCCTTCCCAGCACATCGCCAGCCCTGGGCCTGGGGATGTCCCCAATGC TGTACCTGGCTGACCCCGGATTAAAAGCCTCATCCACGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001142778.2
Synonyms	CBAS1; PFIC4; SDR11E3
Summary	This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Locus ID	80270
MW	49.1

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