UNC13B (NM_006377) Human 3' UTR Clone

Specifications

Product Data
Product Name	UNC13B (NM_006377) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	MUNC13; munc13-2; UNC13; Unc13h2
ACCN	NM_006377
Insert Size	1332 bp
Sequence Data	Insert Sequence (showhide) >SC213990 3’UTR clone of NM_006377 The sequence shown below is from the reference sequence of NM_006377. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAGTCTCGTTCCACGGAGGAGGGGAGCTGAACACCTTCGACTCCTGTGCCAATCAGGCAGCAGCAATTT CACAAATCAGGGCCAGTGGGAGTTAGCTGTGTAACCGGCTTAGGGTCTTTGCAGTCAAGAGGCTGACCC CTTCAGTTAAAGATATTTAAGGAAAAATTTGGGGTGGTGATAATATGGCTTTTCACAGAAAGGGTCATG AAGCCCTGGCCCAACAGGACTGTGGTACTAGGGGCTGGGATGTGGGGTTACCACATGGAGAGATTTTCC ATTAAGAGAGAAGGACAAACATTTCTGAGAGTGTCAGCCATTCTTGGTAGACACCTCTCCACTCCTCAT CCCACCTCTACCCATCTCCATGCCACACCTTATCCAGTTAGACACATACATACCAATCATTAGAAGAAC AAGTTTAGAAGGTGTGGAACTTGTGCCTGGCTGGCTGGGTAGTCAGCTGAGCCTGTTGCTGAGCCCGGT GGTCTGGATTGGAGTATGGCCAGGGCAGGAGTACACAGAATAGAATTTAGACTGTCCCTTGAGTAGAAT CCACTGATTTTCTGTGGCTCCAGTGAGAACAAGGCTTTGAAACTGAACAAGATAACTTCTAGAAATGAA CTGTACTAATCCCTTTCCCCAGATTGTATCATGAGTAGAATCAGGTTCACGTGGTGCTTCAAAGCCCTG AGAAGAATATTTCTTTGGACCCCAGGCACTAGGGGCCACCTGCCTGGGAGTCTCCCTGCCTCACTCCTC TAGGCAGGGGAGTGATGCTTCAGGACGTGACAGGCTGTTCTAACATGTGTCTACCTGAGGGCTAGTTGA AGGATCCAGGAGTATTTTCTTCTTGGGTGGGCCCTGAACAAAGCCAAAAATTGTAGAAACCAGTCTAGA AAAAGTCCTGCTCATCTGTGGCCACTGCCTTCTAGCCGTCCTCCACCTTGCAGAAAGAATCTAGCCTTT GGTCTCTCTCTCTCTCATCGGGGTCATTTGCTATTCCCCTCTGATATTCAACCCTATAGAAGGAGCCTG GACTCTGATCCCTCTGTACAGGCTGGATGGAAGGGGCCCTCCACACTTCCTGGGAGGTCAGAGACAAAC TGTTTCAGAGAGTCAGATGGACTTCCCAAGACTTGTTGAGAGATGTGACATGGTTCTTGGATTTCCTCT GTAGCAGCCTCCTGGACTTCCTGAGGACTCGACATTGTCCACAGATGTACTGGCCATTACATGAAACAA GAAACCAAGCATCTTTGCTGTTGTTAATTATTATATGTGCCATTGTTACAGGAGATTATAGGCTAGTCT GTAATAAATTATCTTATAGCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006377.6
Synonyms	MUNC13; munc13-2; UNC13; Unc13h2
Summary	This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq, Jul 2008]
Locus ID	10497
MW	49.9

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