ILF3 (NM_004516) Human 3' UTR Clone

Specifications

Product Data
Product Name	ILF3 (NM_004516) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CBTF; DRBF; DRBP76; MMP4; MPHOSPH4; MPP4; MPP4110; NF-AT-90; NF90; NF90a; NF90b; NF90c; NF90ctv; NF110; NF110b; NFAR; NFAR-1; NFAR-2; NFAR2; NFAR90; NFAR110; TCP80; TCP110
ACCN	NM_004516
Insert Size	1330 bp
Sequence Data	Insert Sequence (showhide) >SC213912 3’UTR clone of NM_004516 The sequence shown below is from the reference sequence of NM_004516. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TACGGCTATCATGATTTTGGGTCTTCCTAGAGCGTCTAAAAGTATTGCACACAAAATCAACTTTTTACT CCAATTTCCTCCAACTCCAAAACCCAAAGTGTCCGTGCTGTGTCCCTGTGCTTCACTGGGTTTCTCAAC CGTGGCTTTTCACCGCAGCTTGTCTGAAACTCTTAGCCTGCAGAATTTAAGACAATGGCAGTTTTTATC GTGATTTGCCTTTGAACTTGGTCCTATTGAAGTTCACAATAAGTGGAAAACAATTTTTTCAGAGAATGT ATTTTTGTGCAGAATTGCACAGAATTCTAGAGACAGCGTTGTTCGGCATCAAGGCAAAAGCCCACCTTT GCTTTTTATGGAAAGCATTACTTTATTTAAAGAGACAGACAATGACGCATTTTAATCTACCTTTGTCTT AATTTACAGCAGGTTTTGTATGAATTTTTAACCTTTTAACAAACTCCCAAATCTGGTTGATGCCTTTGA CAGTGATGAAAACGATTTCACCACATCTGAATCCAGAGAAACCGGCTTTTTTTCTTATTGCGAGCATGT TAAAACGTTGGGAACATGTGGGGAATTGTATATTGCGCTGAATTAACTTCTCCCGCCTCTTGTAATGCT CTGGTGGGTTCTTGTTTGGGAATGCGATATTTTGTGGCTGGTTTAGCTAGAGAGTGAACTCTCAAAGGT ATCAAAACTGTGCTTCCATTATTAGTGCAAGAAACAGACAGGCTTTAAGGGGTAGATGACGTGAAATTT TGCAAGTCTTAATTACAGCTGCAGATGCATGGGATTCTGGATTTTTTTGTTGCTTTTTAGTTTAATGGG ACTTTAAAAGTAATTGAGGAGAAAGAACCGTGATGTTCCCTGTTTCTCCAGTAAAGGACTGGCTTTTGC TTGGGCAGAGGTGGTGCTGCTGGGTGTGCAGCTGCCACAGACTCCAAAGGCGTAGAAGTTTGTGCCAAC ACACGGAGTCATTCTGGCTCTCTGCTGAGGCCCCTGTTTTCTGGCAGGTGCCCTCCTTGGAAACTGGTT TTGGCTCTGATCAGCGGTTCTTTTTGCAGCAAAGCCTGCATCTGTGTTGACTTGCAAGATTTTGCGTTT ATTCAGGCAAAAACTGGTCAAAATGGTTACTACATGATTTGTTCCCAGAGGTTTGAAACATTCAGTGAA ACTTTTTAAAACTTTGATTGCATGATGTATTTTTTTTTTAGAAAGTTATTGTTTGAGAATAATGTCTTT TTATACCAGGAAAATAGTTATCCTGAATGACGTTGAAAACTCCCCCTCCCCTTTATTTTTTTTTAATCA ATACATGTGAAAGTAACAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004516.4
Synonyms	CBTF; DRBF; DRBP76; MMP4; MPHOSPH4; MPP4; MPP4110; NF-AT-90; NF90; NF90a; NF90b; NF90c; NF90ctv; NF110; NF110b; NFAR; NFAR-1; NFAR-2; NFAR2; NFAR90; NFAR110; TCP80; TCP110
Summary	This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2014]
Locus ID	3609
MW	50.7

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