RUNX1T1 (NM_175636) Human 3' UTR Clone

Specifications

Product Data
Product Name	RUNX1T1 (NM_175636) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AML1-MTG8; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
ACCN	NM_175636
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC213894 3’UTR clone of NM_175636 The sequence shown below is from the reference sequence of NM_175636. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCTTCCACCATAGAGACAACCCCTCGCTAGACGTGAACTCAGAACTGTCGGAGGAAAGACAACACAACC AACGCGAAACCAATTCCTCATCCTCAGATGCTCAAAGTTGTTTTTTTTGTTTGTTTGTTTATTAGATGA ATTATCCTATTTCAGTACTTCAGCAAGAGAGAACCTAACTGTATCTTGAGGTGGTAGTAAAACACAGAG GGCCAGTAACGGGTCGTAATGACTTATTGTGGATAACAAAGATATCTTTTCTTTAGAGAACTGAAAAGA GAGCAGAGAATATAACATGAAATGATAGATTTGACCTCCTCCCTGTTATTTTCAAGTAGCTGGGATTTT AAACTAGATGACCTCATTAACCGATGCTTTACCAAACAGCAAACCAAGAGATTGCTAATTGCTGTTGAA AGCAAAAATGCTAATATTAAAAGTCACAATGTTCTTTATATACAATAATGGAAAAAAAAAAAAGAGGAA AACCCTCAAGGGCATGAGCATTGGATACAGCAGTAGACATTTTAACAAGAAGATGAATGGCGTCCGTGG GTTGCTAACTGAACTTTGAAGACCCGCTACAAAACGCGCAGATGTGCAGCAGATTGGAAGGAGACACAG ATGTTCGGTTTTTTTCCTGTTTCTGAAAAGAAATAATAATATCCAGGTCAACAGAATGAAAAATGAAAG ATGATTTGCAATGGGATGTATGAATACAGCAGCAAGAAAAAAAAATGCCATAATACAAAAGGCTCCATA TATATATATATATATATATATATACACACACACACACGCACATATACACACACACACACACACACACAC ACACACACACACACACACACACACACACACAAGTAAGAGACTCAGCCTGCAGTTAATTAGCATTCTGGC AGTTTTGACATCAGCCAGCTGCCCTAAATAACCCTTCAACGTTTCTTCACTTTTGCAAGGTTCCACAGA GTAAGACATTGGGTCTATTCCAGCTCATTCATTTTATATTGAAAAAAATAATTTTAAAAATGGTGGCTT CAGCTCCAGCCCCTTTCCAAAATTTTTCAACCCCACCCTGTTTGGATTTTTAATTAAAAACTAGTAGTT CTCTTGGTGTTAAAACACTTCTGTCCTGTGAGGTTTCCCAATGGTGTTTTTCTTGTAAATGTGTTGGAC AAATGTGAAGATGCATTGTAGTTTAACCATATGCCCACATTTAGTCTCTTTATTCCTAGTTGGTGAGAA ACCTGTATCTTTCTATGCTGCTTTTATATCTGTATGTATTAGTGATATTTCTCTAGTAGTTAAAAAAAA AAAAAGGAAAAAAAGACTCTTTTTGGTTGTCCTCAAGAAAAGAAAAGAAGAAAAGCTATCTTTCGGAGC TGCTATTTCACTCTCTTATAGGATTTTTTTTTTTCCTGAAAACCAGCATGCTTCACGGAATGCTAACAT ATTGGTGTTTTTGTAAGAGGGATGTACATAAATGTATTTTGCACTGTCACAATGACTCCCTAGGCATGC TTTTTGTTTTTTTTTTTTTTTTTTTGAGCAAATTCTTTTTAAATATGCTAGAGCCATTTCATCAAGTTT AGCTGTAGCATAGAGTAGTCGTGGAATTTTTCTTTTTTTTTTTTTTAAATCATTATTAGGGACTTTTTT AAAAAAATAAAATAACAAGATATCCTACTTTAAAAAAAAAGGACAGTGCATGCATATTGCTGTAAGGTC GTTTAAGTATTTCTAATTTTACAAAAGTAAAAATCATTAGAGCTCCAAATGCTGAGGTGTAGATTGACA GCTTTAACACTGCTGAATGCCAGGTTATACAGTATTCTTACAAAAAGGGAAGTCAGCCAAAGACTGATC TGATGGACCAAAATCGGAATTTTGAAAAGCACCAGTACTACTTTCCAAATGATCAGCAGGTTAAACATG TTCAGCAAGGTATAGTATGAATCCATTAACCCTTCGTTGTCCAGGGTCCAGACCAGAACTACTTGTTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_175636.2
Synonyms	AML1-MTG8; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Summary	This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
Locus ID	862
MW	79.9

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