p63 (TP63) (NM_001114979) Human 3' UTR Clone

Specifications

Product Data
Product Name	p63 (TP63) (NM_001114979) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AIS; B(p51A); B(p51B); EEC3; KET; LMS; NBP; OFC8; p40; p51; p53CP; p63; p73H; p73L; RHS; SHFM4; TP53CP; TP53L; TP73L
ACCN	NM_001114979
Insert Size	1355 bp
Sequence Data	Insert Sequence (showhide) >SC213888 3’UTR clone of NM_001114979 The sequence shown below is from the reference sequence of NM_001114979. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAGCCCCCAAACCGATCAGTGTACCCATAGAGCCCTATCTCTATATTTTAAGTGTGTGTGTTGTATTTC CATGTGTATATGTGAGTGTGTGTGTGTGTATGTGTGTGCGTGTGTATCTAGCCCTCATAAACAGGACTT GAAGACACTTTGGCTCAGAGACCCAACTGCTCAAAGGCACAAAGCCACTAGTGAGAGAATCTTTTGAAG GGACTCAAACCTTTACAAGAAAGGATGTTTTCTGCAGATTTTGTATCCTTAGACCGGCCATTGGTGGGT GAGGAACCACTGTGTTTGTCTGTGAGCTTTCTGTTGTTTCCTGGGAGGGAGGGGTCAGGTGGGGAAAGG GGCATTAAGATGTTTATTGGAACCCTTTTCTGTCTTCTTCTGTTGTTTTTCTAAAATTCACAGGGAAGC TTTTGAGCAGGTCTCAAACTTAAGATGTCTTTTTAAGAAAAGGAGAAAAAAGTTGTTATTGTCTGTGCA TAAGTAAGTTGTAGGTGACTGAGAGACTCAGTCAGACCCTTTTAATGCTGGTCATGTAATAATATTGCA AGTAGTAAGAAACGAAGGTGTCAAGTGTACTGCTGGGCAGCGAGGTGATCATTACCAAAAGTAATCAAC TTTGTGGGTGGAGAGTTCTTTGTGAGAACTTGCATTATTTGTGTCCTCCCCTCATGTGTAGGTAGAACA TTTCTTAATGCTGTGTACCTGCCTCTGCCACTGTATGTTGGCATCTGTTATGCTAAAGTTTTTCTTGTA CATGAAACCCTGGAAGACCTACTACAAAAAAACTGTTGTTTGGCCCCCATAGCAGGTGAACTCATTTTG TGCTTTTAATAGAAAGACAAATCCACCCCAGTAATATTGCCCTTACGTAGTTGTTTACCATTATTCAAA GCTCAAAATAGAATTTGAAGCCCTCTCACAAAATCTGTGATTAATTTGCTTAATTAGAGCTTCTATCCC TCAAGCCTACCTACCATAAAACCAGCCATATTACTGATACTGTTCAGTGCATTTAGCCAGGAGACTTAC GTTTTGAGTAAGTGAGATCCAAGCAGACGTGTTAAAATCAGCACTCCTGGACTGGAAATTAAAGATTGA AAGGGTAGACTACTTTTCTTTTTTTTACTCAAAAGTTTAGAGAATCTCTGTTTCTTTCCATTTTAAAAA CATATTTTAAGATAATAGCATAAAGACTTTAAAAATGTTCCTCCCCTCCATCTTCCCACACCCAGTCAC CAGCACTGTATTTTCTGTCACCAAGACAATGATTTCTTGTTATTGAGGCTGTTGCTTTTGTGGATGTGT GATTTTAATTTTCAATAAACTTTTGCATCTTGGTTTATCTTGCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001114979.2
Synonyms	AIS; B(p51A); B(p51B); EEC3; KET; LMS; NBP; OFC8; p40; p51; p53CP; p63; p73H; p73L; RHS; SHFM4; TP53CP; TP53L; TP73L
Summary	This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. [provided by RefSeq, Aug 2016]
Locus ID	8626
MW	51.3

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