AMPK beta 1 (PRKAB1) (NM_006253) Human 3' UTR Clone
CAT#: SC213854
3' UTR clone of protein kinase AMP-activated beta 1 non-catalytic subunit (PRKAB1) for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
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经常一起买 (2)
Specifications
Product Data | |
Product Name | AMPK beta 1 (PRKAB1) (NM_006253) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | AMPK; HAMPKb |
ACCN | NM_006253 |
Insert Size | 1324 bp |
Sequence Data |
>SC213854 3’UTR clone of NM_006253
The sequence shown below is from the reference sequence of NM_006253. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GTCACCACCTTGTTATACAAGCCCATATGAAGAGCTGGGGGCGGATGGTGGCCCAGGAGACAGCACACC ACCAGGCTCCACACGTGCATGCTTTCCCCAAGAGGGAATGGACTGTACATTGCTCATTTCACACTCTTC AGAAGACATTTCATACCTGCCCTGGTCCTGCTTGAAGGTTTGTCCAGGCAGAGCAGCTCCTGCAGCGCC TCGGTCTGTGACAGTCCTCCTAGCACCCCCATGGCTTTGAGCCTCGGGGACTCATCAAGTCCAAGAAAA GAGGGAGGGGTGGCAGAGGATCTGCAGCCCTGGCCCCGCGGTGCATGAGGCTGGGTGCAGTTCTAAACC TACATTCTCGATTTTTCTTAAGCCAAAAATGAATGCTAACTCCTTTGCCAGTAAAATTCTGGGAAACAG GGACTGAGGCCACACATCATTTCCAGTCATCTGTGTGTTTTTAAGGCCAGCCACTTGTCCCTGTTGAGG CCTGGCTATGGAACTAAATACAGTGTTGGTCTTGCCTGTCCTTCAAAATCAACAACAGATTGTCTCTCG GCTCCAGGGAGGTGTCATTTCTATAGAAATTAGAAGCTTTCTGATTTCTAGATGAGGTTTTACAATTGT TTCTTACAGTCATGTGCACTAAGTACTCTTTTTGTAAGCAGAGGTGGCTGGCTCTGCAGCCTTAAGGCC ATTTTTTAAGTCACCACGTCTAGAAGTCACATGAACTCTGCTCAGCAATAATCTGTTCTCAGAACAGAC TTTTCAACCTGCTGCCGGATTTCTCCATTCAGCTGGATGATCCTCAGGACTGACCAGTTAGCTGGCAGG TTGTCCAGCTTTTTATTCCAGTCATAATAGGTGACAGTGTTAACCGTGAAAACTTGAGAGGCACTCTGC CCTCTTCCCTATAAAATCACACAGCGTGATTTTACAAGGTCCCGTGGCACCTTGCTCAGGACCTCTGCC CCTAGTTAGCAAGACTGCAGCAGTTGCTGTTGCTTATTCTGAAAGGAATGTAGAACTTGACAGCAGCCT TCTGAGTCTGGGTCAGGAAGATGTCCTTTGGACCAAAGCAGACTTCTTTATACGCAGCTCAGTTTCCCG GGAGTCGCCACAGATGTACCCACTAGCCCAGGTTGCTGTGAGTCAGCGGAAGCTCCCGTTATGCCCTTT GCTCCTGGTGGGAGAGGGAGGAGTGAGCTCCCTGGGTTCCAGTATTTACTTGGTATACCTGAGTTTGGG GGTACCCTTTTTTGTGACTTTTCAAAACAGTGAATTACTGTCACCTTGATGGACAAGTTTCAATAAAAC TTTGTAAAAATAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_006253.5 |
Synonyms | AMPK; HAMPKb |
Summary | The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008] |
Locus ID | 5564 |
MW | 48.9 |
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