NMDAR2B (GRIN2B) (NM_000834) Human 3' UTR Clone

Specifications

Product Data
Product Name	NMDAR2B (GRIN2B) (NM_000834) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	DEE27; EIEE27; GluN2B; hNR3; MRD6; NMDAR2B; NR2B; NR3
ACCN	NM_000834
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC213840 3’UTR clone of NM_000834 The sequence shown below is from the reference sequence of NM_000834. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAACTTTCTAGTATTGAGTCTGATGTCTGAGTGAGGGAACAGAGAGGTTAAGGTGGGTACGGGAGGGTA AGGCTGTGGGTCGCGTGATGCGCATGTCACGGAGGGTGACGGGGGTGAACTTGGTTCCCATTTGCTCCT TTCTTGTTTTAATTTATTTATGGGATCCTGGAGTTCTGGTTCCTACTGGGGGCAACCCTGGTGACCAGC ACCATCTCTCCTCCTTTTCACAGTTCTCTCCTTCTTCCCCCCGCTGTCAGCCATTCCTGTTCCCATGAG ATGATGCCATGGGCCCTCTCAGCAGGGGAGGGTAGAGCGGAGAAAGGAAGGGCTGCATGCGGGCTTCCT CCTGGTGTGGAAGAGCTCCTTGATATCCTCTTTGAGTGAAGCTGGGAGAACCAAAAAGAGGCTATGTGA GCACAAAGGTAGCTTTTCCCAAACTGATCTTTTCATTTAGGTGAGGAAGCAAAAGCATCTATGTGAGAC CATTTAGCACACTGCTTGTGAAAGGAAAGAGGCTCTGGCTAAATTCATGCTGCTTAGATGACATCTGTC TAGGAATCATGTGCCAAGCAGAGGTTGGGAGGCCATTTGTGTTTATATATAAGCCAAAAAATGCTTGCT TCAACCCCATGAGACTCGATAGTGGTGGTGAACAGAACAAAAGGTCATTGGTGGCAGAGTGGATTCTTG AACAAACTGGAAAGTACGTTATGATAGTGTCCCACGGTGCCTTGGGGACAAGAGCAGGTGGATTGTGCG TGCATGTGTGTTCATGCACACTTGCACCCATGTGTAGTCAGGTGCCTCAAGAGAAGGCAACCTTGACTC TTTCTATTGTTTCTTTCAATATCCCCAAGCAGTGTGATTGTTTGGCTTATATACAGACAGAGATGGCCA TGTATTACCTGAATTTTGGCTGTGTCTCCCTTCATCCTTCTGGAATAAGGAGAATGAAAATTCTTGATA AAGAAGATTCTGTGGTCTAAACAAAAAAAGGCGGTGAGCAATCCTGCAAGAACAAGGTACATAAACAAG TCCTCAGTGGTTGGCAATTGTTTCAACCAGTTTGAACCAAGAACTTTCCAGGAAGGCTAAAGGGAAACC GAATTTTCACAGCCATGATTCTTTTGCCCACACTTGGGAGCAAAAGATTCTACAAAGCTCTTTTGAGCA TTTAGACTCTCGACTGGCCAAGGTTTGGGGAAGAACGAAGCCACCTTTGAAGAAGTAAGGAGTCGTGTA TGGTAGGGTAAGTGAGAGAGGGGGATGTTTCCAATGCTTTGATCCCTTCTTACTTAACCTGAAGCTAGA CGAGCAGGCTTCTTCCCCCCAAAACTGATTACAACTGCTACAGAGCAGACAGTTAAGAGAAATGAGCTT GACCTTTAAGAGAAATGAGCTGCACTCCATGAGTGCAGCTCTGGAGGTACGAAAAGAGGGGAAGAGACT TGGAAATGGGAGACGGGGGCAGAGAGGGACCCTCCACCACCTCTTTGGGCCTGGCTCCCTGGGAATGTG ACTTGAGCCCAGAGTGAACACTCTTGGTAGAAGCCCTTCTACCTTCCTGCAACACCTTGTTTCCCTCTC AGATTGTACCATTGAGGAATAAAAAAAGATATACATGTATAAAACTCCAGGGATGAGGGTACCAGCAGA ACTGATGCTCCCTTCACTTAACATTGGAAAATTGAGAAGGGAAATGAATATGTATCACTGCCGGTCCTG AAACTTGCGGTAGGGCTATTTATTCTATGGGTCAGTTCCACTGTCCTGCCATCCTCCCCTACACAGGGT GGCATCCAGAGAGCCCCAGGTCTGTGTGGAAGCTTGACTGCAGGATCGCCATGTTGCACACAGGACACA TAAACCAGAAAGGTGCTCATCCTCCTCTGGAAGGAAGCTGCCATGTCTCTTCAAGTCACTCCCTCCAGG GCTGCTCTTCGCCCCTGTTTGCCCTCACTCGTGACCCTTCCTCATCCCGCCCTTGACTGCTGTCCCCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000834.5
Synonyms	DEE27; EIEE27; GluN2B; hNR3; MRD6; NMDAR2B; NR2B; NR3
Summary	This gene encodes a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. The encoded protein is a subunit of the NMDA receptor ion channel which acts as an agonist binding site for glutamate. The NMDA receptors mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation. Naturally occurring mutations within this gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia. [provided by RefSeq, Aug 2017]
Locus ID	2904
MW	74.5

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