BAP1 (NM_004656) Human 3' UTR Clone

Specifications

Product Data
Product Name	BAP1 (NM_004656) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	hucep-6; HUCEP-13; UCHL2
ACCN	NM_004656
Insert Size	1310 bp
Sequence Data	Insert Sequence (showhide) >SC213756 3’UTR clone of NM_004656 The sequence shown below is from the reference sequence of NM_004656. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCTCGCCCCTACAAGGCCAAGCGCCAGTGAGGACTGCTGGCCCTGACTCTGCAGCCCACTCTTGCCGTG TGGCCCTCACCAGGGTCCTTCCCTGCCCCACTTCCCCTTTTCCCAGTATTACTGAATAGTCCCAGCTGG AGAGTCCAGGCCCTGGGAATGGGAGGAACCAGGCCACATTCCTTCCATCGTGCCCTGAGGCCTGACACG GCAGATCAGCCCCATAGTGCTCAGGAGGCAGCATCTGGAGTTGGGGCACAGCGAGGTACTGCAGCTTCC TCCACAGCCGGCTGTGGAGCAGCAGGACCTGGCCCTTCTGCCTGGGCAGCAGAATATATATTTTACCTA TCAGAGACATCTATTTTTCTGGGCTCCAACCCAACATGCCACCATGTTGACATAAGTTCCTACCTGACT ATGCTTTCTCTCCTAGGAGCTGTCCTGGTGGGCCCAGGTCCTTGTATCATGCCACGGTCCCAACTACAG GGTCCTAGCTGGGGGCCTGGGTGGGCCCTGGGCTCTGGGCCCTGCTGCTCTAGCCCCAGCCACCAGCCT GTCCCTGTTGTAAGGAAGCCAGGTCTTCTCTCTTCATTCCTCTTAGGAGAGTGCCAAACTCAGGGACCC AGCACTGGGCTGGGTTGGGAGTAGGGTGTCCCAGTGGGGTTGGGGTGAGCAGGCTGCTGGGATCCCATG GCCTGAGCAGAGCATGTGGGAACTGTTCAGTGGCCTGTGAACTGTCTTCCTTGTTCTAGCCAGGCTGTT CAAGACTGCTCTCCATAGCAAGGTTCTAGGGCTCTTCGCCTTCAGTGTTGTGGCCCTAGCTATGGGCCT AAATTGGGCTCTAGGTCTCTGTCCCTGGCGCTTGAGGCTCAGAAGAGCCTCTGTCCAGCCCCTCAGTAT TACCATGTCTCCCTCTCAGGGGTAGCAGAGACAGGGTTGCTTATAGGAAGCTGGCACCACTCAGCTCTT CCTGCTACTCCAGTTTCCTCAGCCTCTGCAAGGCACTCAGGGTGGGGGACAGCAGGATCAAGACAACCC GTTGGAGCCCCTGTGTTCCAGAGGACCTGATGCCAAGGGGTAATGGGCCCAGCAGTGCCTCTGGAGCCC AGGCCCCAACACAGCCCCATGGCCTCTGCCAGATGGCTTTGAAAAAGGTGATCCAAGCAGGCCCCTTTA TCTGTACATAGTGACTGAGTGGGGGGTGCTGGCAAGTGTGGCAGCTGCCTCTGGGCTGAGCACAGCTTG ACCCCTCTAGCCCCTGTAAATACTGGATCAATGAATGAATAAAACTCTCCTAAGAATCTCCTGAGAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004656.4
Synonyms	hucep-6; HUCEP-13; UCHL2
Summary	This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013]
Locus ID	8314
MW	45.4

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