PLOD2 (NM_182943) Human 3' UTR Clone

Specifications

Product Data
Product Name	PLOD2 (NM_182943) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BRKS2; LH2; TLH
ACCN	NM_182943
Insert Size	1307 bp
Sequence Data	Insert Sequence (showhide) >SC213729 3’UTR clone of NM_182943 The sequence shown below is from the reference sequence of NM_182943. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TACATTGCAGTGTCATTTATAGATCCCTAAGTTATTTACTTTTCATTGAATTGAAATTTATTTTGGATG AATGACTGGCATGAACACGTCTTTGAAGTTGTGGCTGAGAAGATGAGAGGAATATTTAAATAACATCAA CAGAACAACTTCACTTTGGGCCAAACATTTGAAAAACTTTTTATAAAAAATTGTTTGATATTTCTTAAT GTCTGCTCTGAGCCTTAAAACACAGATTGAAGAAGAAAAGAAAGAAAAAACTTAAATATTTATTTCTAT GCTTTGTTGCCTCTGAGAATAATGACAATTTATGAATTTGTGTTTCAAATTGATAAAATATTTAGGTAC AAATAACAAGACTAATAATATTTTCTTATTTAAAAAAAGCATGGGAAGATTTTTATTTATCAAAATATA GAGGAAATGTAGACAAAATGGATATAAATGAAAATTACCATGTTGTAAAACCTTGAAAATCAGATTCTA ACTGGATTTGTATGCAACTAAGTATTTTTCTGAACACCTATGCAGGTCTTATTTACAGTAGTTACTAAG GGAACACACAAAGAATTACACAACGTTTTCCTCAAGAAAATGGTACAAAACACAACCGAGGAGCGTATA CAGTTGAAAACATTTTTGTTTTGATTGGAAGGCAGATTATTTTATATTAGTATTAAAAATCAAACCCTA TGTTTCTTTCAGATGAATCTTCCAAAGTGGATTATATTAAGCAGGTATTAGATTTAGGAAAACCTTTCC ATTTCTTAAAGTATTATCAAGTGTCAAGATCAGCAAGTGTCCTTAAGTCAAACAGGTTTTTTTTGTTGT TGTTTTTGCTTTGTTTCCTTTTTTAGAAAGTTCTAGAAAATAGGAAAACGAAAAATTTCATTGAGATGA GTAGTGCATTTAATTATTTTTTAAAAAACTTTTTAAGTACTTGAATTTTATATCAGGAAAACAAAGTTG TTGAGCCTTGCTTCTTCCGTTTTGCCCTTTGTCTCGCTCCTTATTCTTTTTTTGGGGGGAGGGTTATTT GCTTTTTTATCTTCCTGGCATAATTTCCATTTTATTCTTCTGAGTGTCTATGTTAACTTCCCTCTATCC CGCTTATAAAAAAATTCTCCAACAAAAATACTTGTTGACTTGATGTTTTATCACTTCTCTAAGTAAGGT TGAAATATCCTTATTGTAGCTACTGTTTTTAATGTAAAGGTTAAACTTGAAAAGAAATTCTTAATCACG GTGCCAAAATTCATTTTCTAACACCATGTGTTAGAAAATTATAAAAAATAAAATAATTTTAGAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_182943.3
Synonyms	BRKS2; LH2; TLH
Summary	The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Locus ID	5352
MW	52

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