STAT5A (NM_003152) Human 3' UTR Clone
CAT#: SC213723
3' UTR clone of signal transducer and activator of transcription 5A (STAT5A) for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
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经常一起买 (2)
Specifications
Product Data | |
Product Name | STAT5A (NM_003152) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | MGF; STAT5 |
ACCN | NM_003152 |
Insert Size | 1304 bp |
Sequence Data |
>SC213723 3’UTR clone of NM_003152
The sequence shown below is from the reference sequence of NM_003152. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TTCACCTCTGCCAGAGGCTCCCTCTCATGAATGTTTGAATCCCACGCTTCTCTTTGGAAACAATATGCA ATGTGAAGCGGTCGTGTTGTGAGTTTAGTAAGGCTGTGTACACTGACACCTTTGCAGGCATGCATGTGC TTGTGTGTGTGTGTGTGTGTGTGTCCTTGTGCATGAGCTACGCCTGCCTCCCCTGTGCAGTCCTGGGAT GTGGCTGCAGCAGCGGTGGCCTCTTTTCAGATCATGGCATCCAAGAGTGCGCCGAGTCTGTCTCTGTCA TGGTAGAGACCGAGCCTCTGTCACTGCAGGCACTCAATGCAGCCAGACCTATTCCTCCTGGGCCCCTCA TCTGCTCAGCAGCTATTTGAATGAGATGATTCAGAAGGGGAGGGGAGACAGGTAACGTCTGTAAGCTGA AGTTTCACTCCGGAGTGAGAAGCTTTGCCCTCCTAAGAGAGAGAGACAGAGAGACAGAGAGAGAGAAAG AGAGAGTGTGTGGGTCTATGTAAATGCATCTGTCCTCATGTGTTGATGTAACCGATTCATCTCTCAGAA GGGAGGCTGGGGTTCATTTTCGAGTAGTATTTTATACTTTAGTGAACGTGGACTCCAGACTCTCTGTGA ACCCTATGAGAGCGCGTCTGGGCCCGGCCATGTCCTTAGCACAGGGGGGCCGCCGGTTTGAGTGAGGGT TTCTGAGCTGCTCTGAATTAGTCCTTGCTTGGCTGCTTGGCCTTGGGCTTCATTCAAGTCTATGATGCT GTTGCCCACGTTTCCCGGGATATATATTCTCTCCCCTCCGTTGGGCCCCAGCCTTCTTTGCTTGCCTCT CTGTTTGTAACCTTGTCGACAAAGAGGTAGAAAAGATTGGGTCTAGGATATGGTGGGTGGACAGGGGCC CCGGGACTTGGAGGGTTGGTCCTCTTGCCTCCTGGAAAAAACAAAAACAAAAAACTGCAGTGAAAGACA AGCTGCAAATCAGCCATGTGCTGCGTGCCTGTGGAATCTGGAGTGAGGGGTAAAAGCTGATCTGGTTTG ACTCCGCTGGAGGTGGGGCCTGGAGCAGGCCTTGCGCTGTTGCGTAACTGGCTGTGTTCTGGTGAGGCC TTGCTCCCAACCCCACACGCTCCTCCCTCTGAGGCTGTAGGACTCGCAGTCAGGGGCAGCTGACCATGG AAGATTGAGAGCCCAAGGTTTAAACTTCTCTGAAGGGAGGTGGGGATGAGAAGAGGGGTTTTTTTGTAC TTTGTACAAAGACCACACATTTGTGTAAACAGTGTTTTGGAATAAAATATTTTTTTCATAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_003152.4 |
Synonyms | MGF; STAT5 |
Summary | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013] |
Locus ID | 6776 |
MW | 47.2 |
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