PEX5 (NM_001131023) Human 3' UTR Clone

Specifications

Product Data
Product Name	PEX5 (NM_001131023) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	PBD2A; PBD2B; PTS1-BP; PTS1R; PXR1; RCDP5
ACCN	NM_001131023
Insert Size	1266 bp
Sequence Data	Insert Sequence (showhide) >SC213650 3’UTR clone of NM_001131023 The sequence shown below is from the reference sequence of NM_001131023. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTCCTAACTATGTTTGGCCTGCCCCAGTGACAGTGGGACGGGCTGCCCTGTGAGTGTCCACCTGGAGGG ATCCCCGCTTTGGATGTGATTCCCTCTCCCCAAATGGGCCTACCAAGGGGGCGGGCTGATGACCATAAG CGGTACGGCCTTTCAGGAGCTGCCTCAACGTAGGGGTGGGTAGTCTGTGTTCTAGTTCCTACATAATTG TAGGAAAATGAGCTGTGTCATCTCTGAGTCCCTTGGTAATTCAAGGGCTGTACATCCAGCTACAGATCT CTCTGCTCATCATGCCCTTTCTTGGTGCTGCTTTTTGGGTAGGACCCCACGATTTAGGGTAACTGTTAT CATCAGCTGCCATTTCTGATAGGGTCTACCACATCTGTAATGTCTGTCCTTTCCCCCACTTTTACTGGG AATTGATAGTCCAGCTTCCTTGGGCAGTGTAAGTAGGAGGTTCATCTGCTGTGCGCCTCTAATGTCTGT CTGGATGGGATGTGTTAGGAGTTGGCCTGTTGGGTTGAATTGTTGATTTGGCTGAGCAGAGCTGAGTTT TGGTAGGAGTGCTCATGGTTCTGTCATTCTTGGACCTCTCCTGGCTGAGCTCTGATTCCCTGTGAGCAC GATGCTGATGCAATAGTCCTGTGTCATCACTGCAGCGGTCCTCAGGAGCTGCCAGGGCCAATTGCTACA GAGTGTCTGGGTGTGTGGCATAGGAGGAAGGTTTGCTTGTGAAATGAGGCTGGGTGGGAGCGGGGAGGG ACTAGATCAGAAGAGATCAAGGGCTCTATTCAGGAACGTTGGTGGGAGGACAGAGCAAGTGGGAAGGGG GTATGGTGAGTGCGGCAATCCCTCATCCTCTTAGAAGCACCTGTGAATGGGAATTGAGCCAACTGTTAT AGAAAATTGGTTCAGAAAGTGCAATCTTGCCAGATTTCTAGCAAATAGGTTCAGTGTTACCATAAGCCT TTGCTGTACTTCTTGAAATGTTTCTAGGGGAGAGCATTGGAAAATCCCCTTCCCCCATCTAGATCGAAG GAAGATGAGGGAGCAGCTTGGATTCTTCTCAGTTGTCCCCTGCATGGGGAGATACACTAACCCCCAGAA ATGACTGCTAAGCCTCTTGCCTTGTCTTTAGTAGCTAATGATCAGAGAGATTTTTTTTTTAAACTACCA TGGTCCCAGGATTCCATCCTGAAATTTATTTTTCTTTGTATGAATATGTGTAAATGATTTAAAAATAAA ACTGTAAAATATTTGTACGAAGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001131023.2
Synonyms	PBD2A; PBD2B; PTS1-BP; PTS1R; PXR1; RCDP5
Summary	The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
Locus ID	5830
MW	47.3

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