MMP13 (NM_002427) Human 3' UTR Clone

Specifications

Product Data
Product Name	MMP13 (NM_002427) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CLG3; MANDP1; MDST; MMP-13
ACCN	NM_002427
Insert Size	1301 bp
Sequence Data	Insert Sequence (showhide) >SC213647 3’UTR clone of NM_002427 The sequence shown below is from the reference sequence of NM_002427. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATGCCAGCAAATTCCATTTTGTGGTGTTAAGTGTCTTTTTAAAAATTGTTATTTAAATCCTGAAGAGCA TTTGGGGTAATACTTCCAGAAGTGCGGGGTAGGGGAAGAAGAGCTATCAGGAGAAAGCTTGGTTCTGTG AACAAGCTTCAGTAAGTTATCTTTGAATATGTAGTATCTATATGACTATGCGTGGCTGGAACCACATTG AAGAATGTTAGAGTAATGAAATGGAGGATCTCTAAAGAGCATCTGATTCTTGTTGCTGTACAAAAGCAA TGGTTGATGATACTTCCCACACCACAAATGGGACACATGGTCTGTCAATGAGAGCATAATTTAAAAATA TATTTATAAGGAAATTTTACAAGGGCATAAAGTAAATACATGCATATAATGAATAAATCATTCTTACTA AAAAGTATAAAATAGTATGAAAATGGAAATTTGGGAGAGCCATACATAAAAGAAATAAACCAAAGGAAA ATGTCTGTAATAATAGACTGTAACTTCCAAATAAATAATTTTCATTTTGCACTGAGGATATTCAGATGT ATGTGCCCTTCTTCACACAGACACTAACGAAATATCAAAGTCATTAAAGACAGGAGACAAAAGAGCAGT GGTAAGAATAGTAGATGTGGCCTTTGAATTCTGTTTAATTTTCACTTTTGGCAATGACTCAAAGTCTGC TCTCATATAAGACAAATATTCCTTTGCATATTATAAAGGATAAAGAAGGATGATGTCTTTTTATTAAAA TATTTCAGGTTCTTCAGAAGTCACACATTACAAAGTTAAAATTGTTATCAAAATAGTCTAAGGCCATGG CATCCCTTTTTCATAAATTATTTGATTATTTAAGACTAAAAGTTGCATTTTAACCCTATTTTACCTAGC TAATTATTTAATTGTCCAGTTTGTCTTGGATATATAGGCTATTTTCTAAAGACTTGTATAGCATGAAAT AAAATATATCTTATAAAGTGGAAGTATGTATATTAAAAAAGAGACATCCAAATTTTTTTTTAAAGCAGT CTACTAGATTGTGATCCCTTGAGATATGGAAGGATGCCTTTTTTTCTCTGCATTTAAAAAAATCCCCCA GCACTTCCCACAGTGCCTATTGATACTTGGGGAGGGTGCTTGGCACTTATTGAATATATGATCGGCCAT CAAGGGAAGAACTATTGTGCTCAGAGACACTGTTGATAAAAACTCAGGCAAAGAAAATGAAATGCATAT TTGCAAAGTGTATTAGGAAGTGTTTATGTTGTTTATAATAAAAATATATTTTCAACAGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002427.4
Synonyms	CLG3; MANDP1; MDST; MMP-13
Summary	This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]
Locus ID	4322
MW	51.2

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