C Reactive Protein (CRP) (NM_000567) Human 3' UTR Clone

Specifications

Product Data
Product Name	C Reactive Protein (CRP) (NM_000567) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	PTX1
ACCN	NM_000567
Insert Size	1266 bp
Sequence Data	Insert Sequence (showhide) >SC213454 3’UTR clone of NM_000567 The sequence shown below is from the reference sequence of NM_000567. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GTGTTCACCAAACCCCAGCTGTGGCCCTGAGGCCCAGCTGTGGGTCCTGAAGGTACCTCCCGGTTTTTT ACACCGCATGGGCCCCACGTCTCTGTCTCTGGTACCTCCCGCTTTTTTACACTGCATGGTTCCCACGTC TCTGTCTCTGGGCCTTTGTTCCCCTATATGCATTGCAGGCCTGCTCCACCCTCCTCAGCGCCTGAGAAT GGAGGTAAAGTGTCTGGTCTGGGAGCTCGTTAACTATGCTGGGAAACGGTCCAAAAGAATCAGAATTTG AGGTGTTTTGTTTTCATTTTTATTTCAAGTTGGACAGATCTTGGAGATAATTTCTTACCTCACATAGAT GAGAAAACTAACACCCAGAAAGGAGAAATGATGTTATAAAAAACTCATAAGGCAAGAGCTGAGAAGGAA GCGCTGATCTTCTATTTAATTCCCCACCCATGACCCCCAGAAAGCAGGAGGGCATTGCCCACATTCACA GGGCTCTTCAGTCTCAGAATCAGGACACTGGCCAGGTGTCTGGTTTGGGTCCAGAGTGCTCATCATCAT GTCATAGAACTGCTGGGCCCAGGTCTCCTGAAATGGGAAGCCCAGCAATACCACGCAGTCCCTCCACTT TCTCAAAGCACACTGGAAAGGCCATTAGAATTGCCCCAGCAGAGCAGATCTGCTTTTTTTCCAGAGCAA AATGAAGCACTAGGTATAAATATGTTGTTACTGCCAAGAACTTAAATGACTGGTTTTTGTTTGCTTGCA GTGCTTTCTTAATTTTATGGCTCTTCTGGGAAACTCCTCCCCTTTTCCACACGAACCTTGTGGGGCTGT GAATTCTTTCTTCATCCCCGCATTCCCAATATACCCAGGCCACAAGAGTGGACGTGAACCACAGGGTGT CCTGTCAGAGGAGCCCATCTCCCATCTCCCCAGCTCCCTATCTGGAGGATAGTTGGATAGTTACGTGTT CCTAGCAGGACCAACTACAGTCTTCCCAAGGATTGAGTTATGGACTTTGGGAGTGAGACATCTTCTTGC TGCTGGATTTCCAAGCTGAGAGGACGTGAACCTGGGACCACCAGTAGCCATCTTGTTTGCCACATGGAG AGAGACTGTGAGGACAGAAGCCAAACTGGAAGTGGAGGAGCCAAGGGATTGACAAACAACAGAGCCTTG ACCACGTGGAGTCTCTGAATCAGCCTTGTCTGGAACCAGATCTACACCTGGACTGCCCAGGTCTATAAG CCAATAAAGCCCCTGTTTACTTGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000567.3
Synonyms	PTX1
Summary	The protein encoded by this gene belongs to the pentraxin family which also includes serum amyloid P component protein and pentraxin 3. Pentraxins are involved in complement activation and amplification via communication with complement initiation pattern recognition molecules, but also complement regulation via recruitment of complement regulators. The encoded protein has a calcium dependent ligand binding domain with a distinctive flattened beta-jellyroll structure. It exists in two forms as either a pentamer in circulation or as a nonsoluble monomer in tissues. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. [provided by RefSeq, Aug 2020]
Locus ID	1401
MW	47.2

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