KPNB1 (NM_002265) Human 3' UTR Clone

CAT#: SC213423

3' UTR clone of karyopherin (importin) beta 1 (KPNB1) for miRNA target validation



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CNY 4,845.00


货期*
3周

规格
    • 10 ug

Cited in 1 publication.

Product images

经常一起买 (2)
Firefly luciferase assay kit, 150 assays
    • 1 kit

CNY 1,520.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00

Specifications

Product Data
Product Name KPNB1 (NM_002265) Human 3' UTR Clone
Vector pMirTarget
Synonyms IMB1; Impnb; IPO1; IPOB; NTF97
ACCN NM_002265
Insert Size 2000 bp
Sequence Data
>SC213423 3’UTR clone of NM_002265
The sequence shown below is from the reference sequence of NM_002265. The complete sequence of this clone may contain minor differences, such as SNPs.
Blue=Stop Codon Red=Cloning site

GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
GAACTGAGGAAACTGAAGAACCAAGCTTGATCTGTTACCATTGGGATGATAACCTGAGGACCCCCACTG
GAAATCTCCCATCTTTTGAAAAACCTGGAAGTGAGGAGTGTGCACGGATGCTGAATGTTTGGGAATGAG
AGGATGAGTGAGTGAGGCTTGAAAACACACCACATTGAAAATCCTGCCACAGCAGCAGCCGCAGCCGCC
AACAGCAGCGCTGTTAGTGAGCTAAGTAAGCACTGACTTCGTAGAAAACCATAACATCGGCCATCTTGG
AAAAGAGAAAAACAATGGAGTTACTTATTTAAAAAAAAAGAAAGAAAGTTATCTCTTCCCAGGAGAGGC
TAGAAGTAGCTTTTCTGTCTTTTGGCCAGTGCCGAGTGGAATGCCTGGTTTGGGGGAGGAGGAGGGACT
GGGTTCAGCTGTGGTGCTTTGTTGTAAAAGGCAGCCTGGCCTTTGCTACTGAGGAGAAAGATGGAGCCT
GGGTCTCAAGCCCACCTTCGCTGTACCTTTGCCACATGGTACTGTATGCTTGCCAGCTAGAAGGAGGGT
CAGGGATTTTTTACAGTCTGAGAATGAGTGTGTGTGAGTGAGGCGGTATCCACATTCTCAACTTCAAGT
CATTGCAGTTTCTTTTTCCCAGAAAACAAGGGGTTAGATGTTGCATTTCATAAAACTAACCGAAGTTTT
GTTTACTGATGCAGCACAAGAGATGTAAAAAAAAAAAAAAAAAAAAAAAAAAAAACACACACACAGAGG
AAAGACGCTCTTTAGGTTTTGTTTTGTTTTTTTTTTTTGGTTTTGTTTTTTGTTTTTTTTACTCTAGGG
AAAACACTGACGAATGGTCAGAGCTCCTATCCTGATCTTTTCATCAAGGCGCCTTTCCTAATAATATGG
TTCAACTGTGAATGTAGAAGTGGGGGGGAGGGGGGAGAAAAAGAAAACTCTGGCGTTAGAGGATATAGA
AAAATATAAGTACAATTGTTACAAATAACGCAGACTTCAAAAACAAAAAAATCACAACCCAAACAAACC
AAAATTTAAATGATCAGAATTGGCAGCACAAAGAAAACGCCCTCTCCTGACTTGTATTGTGGCAGTCTG
AACGCCCCCAGAAAATTGTGCCAAAGAGTTTAGAAAAATAAATATACAATAAAAGTAAACACATACACA
CAAAACAGCAAACTTCAGGTAACTATTTTGGATTGCAAACAGGATAAATTAAATGTTCAAACAATCTGA
TAAAATAACCATTTGGAAACTGCTTGGCCTTCTGTTCTTTTATTTGATTGACTACAATGCGGTATTGGT
CTCTTGCTGCACTTCAAAAGCAACCAACAAAACAAAAACAAAAAAAAGTGTGTGTTGTGTGAATACACA
CACACACTAACTAGAAGTCTTGTGATGAAAATGGCACTTGGAAAAGGTTTTATTTTTCCACTGAAGTTG
AAGGTTAATAAAATGGTGTCAAACGTCCCCTGGTCACACACTTGAATATTTTTTTAGAAGTGTGATGTG
GTATGATTACCATAAATCAGACTTAATTATTTTCCCTTTTACAAGGGAACAGGGCATCCTGAATTTTAG
AGCCTTTCAGCAATAAGAAGGGATGTTGGTGAGCTTTGATCCTCTTTTGGTTTTGCAGTTGTTAGGAGT
TTTTGCTGGCATTTTGAATATGCTGCTTTCAGAAAAACCAAGGAAGTTTTAAAATTGCTTCCTGGTCCT
TAGAGGACTAAAAACAAGACCCTCATTCCCACTTTCATTTCCACTCTAGCAAAAACTGGGCTTGCGTTT
TTCTCCAACTCCTCGTTTATATCCTCCCTTCCATGTCCAAGCCTTCCATTCCTAAGTGGGATTGGCTCA
GTTTTGCCCATCCATATGGCAGCATCTCTAATAGCTCTTGTACAGGGTATCAGATATTGTGCCTTTTGG
TGCCAGGTTCAAAGTCAAGTGCCGATCTATGAACCAGTGTACAAAAAAAAAAAAATCCAGGTATTTGA
ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites SgfI-MluI     
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq NM_002265.6
Synonyms IMB1; Impnb; IPO1; IPOB; NTF97
Summary Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]
Locus ID 3837
MW 75.5
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Citations (1)

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