Phospholipase C gamma 1 (PLCG1) (NM_182811) Human 3' UTR Clone

Specifications

Product Data
Product Name	Phospholipase C gamma 1 (PLCG1) (NM_182811) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	NCKAP3; PLC-II; PLC1; PLC148; PLCgamma1
ACCN	NM_182811
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC213201 3’UTR clone of NM_182811 The sequence shown below is from the reference sequence of NM_182811. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACTCGGGTCAATGGAGACAACCGCCTCTAGTTGTACCCCAGCCTCGTTGGAGAGCAGCAGGTGCTGTGC GCCTTGTAGAATGCCGCGAACTGGGTTCTTTGGAAGCAGCCCCCTGTGGCGGCCTTCCGGGTCTCGCAG CCTGAAGCCTGGATTCCAGCAGTGAATGCTAGACAGAAACCAAGCCATTAATGAGATGTTATTACTGTT TTGGGCCTCCATGCCCCAGCTCTGGATGAAGGCAAAAACTGTACTGTGTTTCGCATTAAGCACACACAT CTGGCCCTGACTTCTGGAGATGGATCCTTCCATCTTGTGGGGCCAGGACCATGGCCGAAGCCCCTTGGA GAGAGAGGCTGCCTCAGCCAGTGGCACAGGAGACTCCAAGGAGCTACTGACATTCCTAAGAGTGGAGGA GGAGGAGGAGCCTTGCTGGGCCAGGGAAACAAAGTTTACATTGTCCTGTAGCTTTAAAACCACAGCTGG GCAGGGTGAGAAGCTAGATGCCCCTGCAGTTTGGCCCTGGAGCCAGGGCAGAGGAATGTAGGGCCTGCA TGGAGAAGGGTTCTGCCCTGCCTGAGGAGGAGGACACAGCACAAGGGCACATTGCCCATGGCTGGGAAC ATGACCCAGCCTGAAAGATACAGGGGATCATGTTAAAAATAGCAGTATTATTTTTCGTCTCAATGGTAT TGTAACTAAGTTATTTACTCCTCCTGCTCCTCACCCCTGTAGGGAAACCTTGGAGAGGAGAGTGGCAGG TGGGCTGCCTGCTGTGTTAAGAGGACTTAGTTTGTGATGTAAGGCACTGTCAGGAATGGGGGGCGGGCC AGGGTGGGAAGAGAAGAAATAGCAGAGCCTATTTTGGTGAGGTTTTTTGTTTTTAAGTCAAAGAAGACT CAGTATGCTTTCCCTGAGGAATGAAAAAGGGATTGAGGAGTTGCCTGACTCCTGGGTGGGTGGGGTACA GGCAGTTAGGTGCTGAATGAAGCTGCCATCCTTGCTGCAGCTTCTAACTGGTAAAAAGATCCAGGGATG GAGATGGGAAGGTTAGAAAGGCAGCCCTCACCTCTGAGGACAGAGGCCGGGGTCCAGGCCCGTGGGCGC AAAGGTGCCTCATAGCATAGCCAGCATTCAGCACACACAAACCTACTGCCCACATTTGGGCTCAGGGTT GGCCATTTGCTAGTTCTGCTGCCCTCTTAAGATCTGACTGCCAAATAAATCATCCTCATGTCCTTTTTC CTTTGACTTGTATGCTCTTTCGGGGGCTCAGGAAAGCCTGTTGCATGGGACATGCTCACTAGAAACAGT CGCCAGATGATTATTCTGCAGTAGAAGCAGGTAGGAAATTTCTGGAAATTTCTCAGGTTAAGCAGCAAG AGCTGTAACCCCTCCTCTGGGCTAACAGGAGTTGTGGGTCCACTCTCTCCTGCCCACCCTCTGAGGGTG TGTCTGAGCAGAGTACATCCTGCCTGGGTTCTTTGTGGCCAGCCAGTTTTGGTGGTGAGCTGGAAACAA CCAGAGCCCCTTTCCAGTTCCACAGAAACCTCTCCTTTCAAAAATGTTGCATTCAGTTCGTTAACACTG CCAGGTGCCATTCTGATTGCCTCTAGGACTTGGCAGCTGAAATCTCTGGGCCCTTTCAACACAGTTGAA AGGCCCTTCTCTTCCTGAAGCTCTGTTTCCATAGTTGGCTGTGCTGGGATGGAACAAAAATGACGCCAC ACAAAAAATTTAAGATAGATCCGGTTCCGTGGATGACATGAACTGATGATAGCCAGTATCAAACAGCGA TAGTGCTCAGGTTCTTGTGTGACTTTCTTTTACAGCTTCACAGTCCCAGTTCATAGAGAGGAGGGTGGC TTTTTCCCATACACAAGAAGGTGGTGGGTGGGAATTCACCTGGGCCCTCATGATCCATGTTTCCTCTCT AGGTTTTTATGGCCTGGAGAGAAAGGTTTCCTATCAGAGAAGGAAGAGGACTGTGTAGGCCCTTCTGT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_182811.2
Synonyms	NCKAP3; PLC-II; PLC1; PLC148; PLCgamma1
Summary	The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Locus ID	5335
MW	73.6

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