GIRK1 (KCNJ3) (NM_002239) Human 3' UTR Clone

Specifications

Product Data
Product Name	GIRK1 (KCNJ3) (NM_002239) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	GIRK1; KGA; KIR3.1
ACCN	NM_002239
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC213044 3’UTR clone of NM_002239 The sequence shown below is from the reference sequence of NM_002239. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGAAAAATGAACTCTGATCGCTTCACATAACAAAGCACTCCCTTAGGCATTATTTAATGTTTGATTTAG TAATAGTCCAATATTTGGCGATGAGGTAATTCTCCCTAAGGAATCTGAAAGTATATTTTCCTCCCAGTT CTACAAGCATATTTGAGAACCCTTCCTTTCCCAAGTATTGCGAATGTGCAGAAAGCAACAGTTACGGAG GGAGGACATCATAAGGAAGTTATTAACGGGCATGTATTATCACATCAAGCATGCAATAATGTGCAAATT TTGCATTTAGTTTTATGGCATGATTTATATATGGCATATTTATATTGTATATTCTGGAAAAAAAATATA TATATATATTTAAAGGGGAGATACTCTCCCTGACATTTCTAACATATGTATTAAGCCAAACATGAGTGA ATAGCTTTCAGGGCGATAAAACTAAATATATGTCTGTGTGTGTGTGTGTATGTATACACACATATACAT ATATATATACACATACATACACATACATACATACATACATATATATCTGATAAAATTGTGATGTTTTGT TCAAAGTTGTAGTTCTTGTGCATGTTTACTTTATTAGAGTAGGAAGGCTACTGGCATTAATTATTAATA CCAAATATTTTAGCCTTAAATTTTTGTCATTTTAAAATCTGATTTAATGTTTTCTGCTGTTTAAGGTCT TGGGAGGCTTTCAATTGTATTTTATATGAGAGAATCACACAAGTTTGTGCTATCTATGGCCCTGCAAAA ATATAACCATTACATGTTTAAATTGTAAATTTTAGAGCATACCAGTACTCAGTATAGCATTGAACATTT CTTATGATTTTTAAAAGTTGCTAGTACTGGGGAGAAATAATTGTTGATTAATTTGAGAATTATTCCTTT CCTAGACTAATTAAAATCTGGAAATCTGTTTTGTATATGATCTAATACAAAGATGAGCTCTGAACAAAC ACTGAATCATGTTAATAGACAGTAGCCAAGTTATATTGAATATATCAGAATCTGTGTGAAGTTACACAA TTAATTGTCCCTGTTTCAAACTGAGTAAATTGGAAACATTTTCTTTCTTTTTCTGGAAATTTTGTCCAT TTTAAAAACCAATCATTTTAAGAAGACATGACAATGCAATGAAACAGATGATAAATATTTATGCTTAAA ATATGTATGTCTAATTGAGTCTCTTTTTTATTCTGTTTTCTTGTTTATGGCATTTGTTGTAACAGGATA GACTTTTTCCTCACCTAGGAAACCTATCCCATGCCTGTCACTTATAGTTCAGGAGGAAGTTTTTGCACA GACCAGAGAGAAATTAAAATTAGATGATAAATTGAAGATATCTTACACACAGTTTTTTGGTGAACACTG ATTTTATTGGTGTCTTAGATCCCTAGTCTACCCAAATAATTTTAACAGTACTGTTTTTTCTAATCCTGA AGTCTGATATTTATGACTCATTAGCAGGAATCAAAACTAGTGATCAGTAGAACACTTTCAAAATAAAAA TTTGGAATGCAGACTTTTATGAAAATTTAAAAGTGCTCCTTAACAGAATATCATGGGTTTTCCTATAAA ACTTCTTTAAGTATTGTAATTCCAGTCTGCCCCAACTTTAAAAAAAATTCTTATTAATATGTCAGTCAT TAATTGCTAGTTTGGGCTCTCATTATTTCCTGTTTTTTAACAATTTTGTGATAATTTTATTATTGGCAA ATTAATACATCAACACTTAAATCATTGACTATAATAATACCTTCTGGCTACCTCTGTATCAACCAAATT CTGTAGGTGCAAACATATACCAGGGAATTCTTACTGGCAAAATGATCAATCTGGAGTGTGCATCCACTG TGAATGGAGCAAATTGCCCTATACCCATTGATAACCTAGCTTTCTTAGTTTGTAGATGTAGGAAACAAA ATAGTGACAGAGAGAGAAGGGGGTCCACAGGGCATGGTATATTTATCAGCAGTGGAAAAAAAGTGCAT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002239.4
Synonyms	GIRK1; KGA; KIR3.1
Summary	Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, ataxia, and Parkinson's disease. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, May 2012]
Locus ID	3760
MW	78.2

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