STAT6 (NM_003153) Human 3' UTR Clone

Specifications

Product Data
Product Name	STAT6 (NM_003153) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	D12S1644; IL-4-STAT; STAT6B; STAT6C
ACCN	NM_003153
Insert Size	1194 bp
Sequence Data	Insert Sequence (showhide) >SC212972 3’UTR clone of NM_003153 The sequence shown below is from the reference sequence of NM_003153. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATGGACCTAAGGGCCAACCCCAGTTGGTGATCCCAGCTGGAGGGAGAACCCAAAGAGACAGCTCTTCTA CTACCCCCACAGACCTGCTCTGGACACTTGCTCATGCCCTGCCAAGCAGCAGATGGGGAGGGTGCCCTC CTATCCCCACCTACTCCTGGGTCAGGAGGAAAAGACTAACAGGAGAATGCACAGTGGGTGGAGCCAATC CACTCCTTCCTTTCTATCATTCCCCTGCCCACCTCCTTCCAGCACTGACTGGAAGGGAAGTTCAGGCTC TGAGACACACCCCAACATGCCTGCACCTGCAGCGCGCACACGCACGCACACACACATACAGAGCTCTCT GAGGGTGATGGGGCTGAGCAGGAGGGGGGCTGGGTAAGAGCACAGGTTAGGGCATGGAAGGCTTCTCCG CCCATTCTGACCCAGGGCCTAGGACGGATAGGCAGGAACATACAGACACATTTACACTAGAGGCCAGGG ATAGAGGATATTGGGTCTCAGCCCTAGGGGAATGGGAAGCAGCTCAAGGGACCCTGGGTGGGAGCATAG GAGGGGTCTGGACATGTGGTTACTAGTACAGGTTTTGCCCTGATTAAAAAATCTCCCAAAGCCCCAAAT TCCTGTTAGCCAGGTGGAGGCTTCTGATACGTGTATGAGACTATGCAAAAGTACAAGGGCTGAGATTCT TCGTGTATAGCTGTGTGAACGTGTATGTACCTAGGATATGTTAAATGTATAGCTGGCACCTTAGTTGCA TGACCACATAGAACATGTGTCTATCTGCTTTTGCCTACGTGACAACACAAATTTGGGAGGGTGAGACAC TGCACAGAAGACAGCAGCAAGTGTGCTGGCCTCTCTGACATATGCTAACCCCCAAATACTCTGAATTTG GAGTCTGACTGTGCCCAAGTGGGTCCAAGTGGCTGTGACATCTACGTATGGCTCCACACCTCCAATGCT GCCTGGGAGCCAGGGTGAGAGTCTGGGTCCAGGCCTGGCCATGTGGCCCTCCAGTGTATGAGAGGGCCC TGCCTGCTGCATCTTTTCTGTTGCCCCATCCACCGCCAGCTTCCCTTCACTCCCCTATCCCATTCTCCC TCTCAAGGCAGGGGTCATAGATCCTAAGCCATAAAATAAATTTTATTCCAAAATAACAAAATAAATAAT CTACTGTACACAATCTGAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003153.5
Synonyms	D12S1644; IL-4-STAT; STAT6B; STAT6C
Summary	The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Locus ID	6778
MW	43.2

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