CISH (NM_145071) Human 3' UTR Clone

Specifications

Product Data
Product Name	CISH (NM_145071) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BACTS2; CIS; CIS-1; G18; SOCS
ACCN	NM_145071
Insert Size	1148 bp
Sequence Data	Insert Sequence (showhide) >SC212905 3’UTR clone of NM_145071 The sequence shown below is from the reference sequence of NM_145071. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TACCTCCGACAGTACCCCTTCCAGCTCTGACTGTACGGGGCAATCTGCCCACCCTCACCCAGTCGCACC CTGGAGGGGACATCAGCCCCAGCTGGACTTGGGCCCCCACTGTCCCTCCTCCAGGCATCCTGGTGCCTG CATACCTCTGGCAGCTGGCCCAGGAAGAGCCAGCAAGAGCAAGGCATGGGAGAGGGGAGGTGTCACACA ACTTGGAGGTAAATGCCCCCAGGCCGCATGTGGCTTCATTATACTGAGCCATGTGTCAGAGGATGGGGA GACAGGCAGGACCTTGTCTCACCTGTGGGCTGGGCCCAGACCTCCACTCGCTTGCCTGCCCTGGCCACC TGAACTGTATGGGCACTCTCAGCCCTGGTTTTTCAATCCCCAGGGTCGGGTAGGACCCCTACTGGCAGC CAGCCTCTGTTTCTGGGAGGATGACATGCAGAGGAACTGAGATCGACAGTGACTAGTGACCCCTTGTTG AGGGGTAAGCCAGGCTAGGGGACTGCACAATTATACACTATTTATTTATTTATTCTCCTTGGGGTTGGT GTCAGGGGCGAGCCAACCCCACCTCTATGCCCTGAGCCCTGGTAGTCCAGAGACCCCAACTCTGCCCTG GCTTCTCTGGTTCTTCCCTGTGGAAAGCCCATCCTGAGACATCTTGCTGGAACCAAGGCAATCCTGGAT GTCCTGGTACTGACCCACCCGTCTGTGAATGTGTCCACTCTCTTCTGCCCCCAGCCATATTTGGGGAGG ATGGACAACTACAATAGGTAAGAAAATGCAGCCGGAGCCTCAGTCCCCAGCAGAGCCTGTGTCTCACCC CCTCACAGGACAGAGCTGTATCTGCATAGAGCTGGTCTCACTGTGGCGCAGGCCCCGGGGGGAGTGCCT GTGCTGTCAGGAAGAGGGGGTGCTGGTTTGAGGGCCGCCACTGCAGTTCTGCTAGGTCTGCTTCCTGCC CAGGAAGGTGCCTGCACATGAGAGGAGAGAAATACACGTCTGATAAGACTTCATGAAATAATAATTATA GCAAAGAACAGTTTGGTGGTCTTTTCTCTTCCACTGATTTTTCTGTAATGACATTATACCTTTATTACC TCTTTATTTTATTACCTCTATAATAAAATGATACCTTTCATGTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_145071.4
Synonyms	BACTS2; CIS; CIS-1; G18; SOCS
Summary	The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Locus ID	1154
MW	41.6

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