PKC eta (PRKCH) (NM_006255) Human 3' UTR Clone

Specifications

Product Data
Product Name	PKC eta (PRKCH) (NM_006255) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	nPKC-eta; PKC-L; PKCL; PRKCL
ACCN	NM_006255
Insert Size	1175 bp
Sequence Data	Insert Sequence (showhide) >SC212876 3’UTR clone of NM_006255 The sequence shown below is from the reference sequence of NM_006255. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCCTATGTGTCTCCAGAATTGCAACCATAGCCTTATGGGGAGTGAGAGAGAGGGCACGAGAACCCAAAG GGAATAGAGATTCTCCAGGAATTTCCTCTATGGGACCTTCCCAGCATCAGCCTTAGAACAAGAACCTTA CCTTCAAGGAGCAAGTGAAGAACTCTGTGAAGGATGGAACTTTCAGATATCAACTATTTAGAGTCCAGA GGGAGCCATGGCACTAGAAATAGTTGATAATGAAATGAGATTTTATGAAGTATACCGCTCCACCTATGA GCGTCTGTCTCTGTGGGCTTGGGATGTTAACAGGAGCCAAAAGGAGGGAAAGTGTGAAGAATAAAGTAG ATCTGAGAAATTCTGAGCCAATCAGGCTTCTTAATTCAAGAGACAAACCAAGACGTTCTGTCAACTGTG CTGTGCTCTTCTTTAAGCCAATGAACCCCAATTCCTGGCAGTCTACAAGAAGTCTCTTAATGCTAATGA AGAATTTAAAGGTCTTTTTAAGGAAATGAAGGGCTTTCCAAATAGAATGATTTACTCTGAAGAAACAAA CAATGGTATCTCTGAAACTCACAACCTAAAGCCCAATCTTGAAAATATGTTGTGCACCAAGACGACTGC TTCAGCTTCTTCTCTTATCCTTACTTTCTTTAATAGATATTTATTAAACTGTCCAGTGAAAAGGTGCCA CAATGCCCAGTATTGTAAACAACAGGTTTGCATTCATGAAGCTTTCATTCATTCTGGAGTCTACTAATT TACCTGAATGGTGTTTGCATTCTGTGAAATGCCTCTCCACGTTGCATATGTCACACTTTTGTCTGCACA TAACTCTTTTTTCACAAGAAGGGTCACTGCCACAACAGCACAGTCAGCGGGTGAATTACAGGTGCCTGC TGCCTGCCTACCTGGGTAATCTGATCTTGTCTGTATCGCCGTGTGCTCATCACTGAAGAATTGCAGGCC ACTCATGTCAGTGACCAGATTTGTGGCTTATAAACATTAGCAGTTTATTTATGTTTTAAGATGCAAAGA TGTGTGTTTGATATTCACTTTAATAATTAGAAATGGATCTTGTAAACAGGGCATATATCAAAGATGACC TTATAATATGTACCCGAATATACAGTTCAAGAATTTTGTCTGACTGGAAATAAATGCATTTTGTAGCAA AA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006255.5
Synonyms	nPKC-eta; PKC-L; PKCL; PRKCL
Summary	Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene. Mutations in this gene are associated with susceptibility to cerebral infarction. [provided by RefSeq, Sep 2015]
Locus ID	5583
MW	44.5

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