TL1A (TNFSF15) (NM_005118) Human 3' UTR Clone

Specifications

Product Data
Product Name	TL1A (TNFSF15) (NM_005118) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	TL1; TL1A; TNLG1B; VEGI; VEGI192A
ACCN	NM_005118
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC212724 3’UTR clone of NM_005118 The sequence shown below is from the reference sequence of NM_005118. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAAACCTTCTTTGGAGCCTTCTTACTATAGGAGGAGAGCAAATATCATTATATGAAAGTCCTCTGCCAC CGAGTTCCTAATTTTCTTTGTTCAAATGTAATTATAACCAGGGGTTTTCTTGGGGCCGGGAGTAGGGGG CATTCCACAGGGACAACGGTTTAGCTATGAAATTTGGGGCCCAAAATTTCACACTTCATGTGCCTTACT GATGAGAGTACTAACTGGAAAAAGGCTGAAGAGAGCAAATATATTATTAAGATGGGTTGGAGGATTGGC GAGTTTCTAAATATTAAGACACTGATCACTAAATGAATGGATGATCTACTCGGGTCAGGATTGAAAGAG AAATATTTCAACACCTTCCTGCTATACAATGGTCACCAGTGGTCCAGTTATTGTTCAATTTGATCATAA ATTTGCTTCAATTCAGGAGCTTTGAAGGAAGTCCAAGGAAAGCTCTAGAAAACAGTATAAACTTTCAGA GGCAAAATCCTTCACCAATTTTTCCACATACTTTCATGCCTTGCCTAAAAAAAATGAAAAGAGAGTTGG TATGTCTCATGAATGTTCACACAGAAGGAGTTGGTTTTCATGTCATCTACAGCATATGAGAAAAGCTAC CTTTCTTTTGATTATGTACACAGATATCTAAATAAGGAAGTATGAGTTTCACATGTATATCAAAAATAC AACAGTTGCTTGTATTCAGTAGAGTTTTCTTGCCCACCTATTTTGTGCTGGGTTCTACCTTAACCCAGA AGACACTATGAAAAACAAGACAGACTCCACTCAAAATTTATATGAACACCACTAGATACTTCCTGATCA AACATCAGTCAACATACTCTAAAGAATAACTCCAAGTCTTGGCCAGGCGCAGTGGCTCACACCTGTAAT CCCAACACTTTGGGAGGCCAAGGTGGGTGGATCATCTAAGGCCGGGAGTTCAAGACCAGCCTGACCAAC GTGGAGAAACCCCATCTCTACTAAAAATACAAAATTAGCCGGGCGTGGTAGCGCATGGCTGTAATCCTG GCTACTCAGGAGGCCGAGGCAGAAGAATTGCTTGAACTGGGGAGGCAGAGGTTGCGGTGAGCCCAGATC GCGCCATTGCACTCCAGCCTGGGTAACAAGAGCAAAACTCTGTCCAAAAAAAAAAAAATAAAATAATAA CTCCAAGCCTTTAAAAAATATCATCTGAAACTGTTACATCAGATTTCTGGCACTCTACTGACTGTGGAA GATAGCCAGCTGACTGGAAGATAGCCAGCTGATTAGTTCCCTGAAGAAACCTGAAGACAGATACCTGGT TAACTAGATCAACTACACTGCCAACTTGTTTGATGCTGAGAGACAATGGACTTATTCCATGGGGGAAGG GAAAAAAGAAGTCAATCACCAAATCTGAAGAAGTTAACCTAGATCTTTGAGGTTTGATTTGCAACTTTA TATGCAGAGTATTATGTGGGTATTTTCCCTTAAAATATTCAAAGGGATTTACATATGGGATTAGCTAAT GAGCCTAGCCAAGACCTTCCCTGGAGGACAGGCTGGTCATTGCGGAGGTCCCTTCTGTGCTTCAGTGGG TTCATATCCTCTAGTCCGTATGATTTTCCTACGCTAATATGTCAAGGGCAGGAGAGGCAGCTCTGTTCT CCTAGCCTTTGTTGACTTGTCTGCAAAGCAGGAATCTGCCCATTTGTTTCCAAGGAGCAAATGAGCTCA TGAGAATGAAAGATGTTAACTTCATGCATTCTGTGCCATCTGAGCATTTCGGTATTATATGACTGGTGA CCCTTGGCCCGTATTATAAATGCTTCCTATCCTGGGAGACCTCATGGATGAGTCTGAGAGGAAATTTGG CACCAAAATCACTCTCACTCTGGTTTCCAGTAGACTATAGAGGCAGAGAGGCATTTGAGAGGCTCCTGA GCAAAGTGTCCAGTGTAGCAGGAGCACTTCATTAATATTTATTGAGTTATAATTAAATAAAAATTAAT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_005118.4
Synonyms	TL1; TL1A; TNLG1B; VEGI; VEGI192A
Summary	The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
Locus ID	9966
MW	76.5

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