INPP5E (NM_019892) Human 3' UTR Clone

Specifications

Product Data
Product Name	INPP5E (NM_019892) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CORS1; CPD4; JBTS1; MORMS; pharbin; PPI5PIV
ACCN	NM_019892
Insert Size	1086 bp
Sequence Data	Insert Sequence (showhide) >SC212571 3’UTR clone of NM_019892 The sequence shown below is from the reference sequence of NM_019892. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AACTCCAGCACCATCTGCTCCGTTTCTTGAAGTTTGCTGAACGAGGACTCACAGCTGCAACGTGGGGTG ATTGTATTGATCAAAACCCACTGGGAAGGACAAAGAGTTTGCCGCCTTTCGGGGATCCGAGGGACTGTG GCGACCGTGCCTCTGTGCCAGCGTCCCAGGAAGGAAGCCAACCCTGAGCGAGCCTGTCCTCTGTGGCAG GTCCACACGGTGTGGGTGGGCAGGGCTTGGACCCCCGTCTCCATGGCAGGTCCATACAGCATGGGTGGC AGGGTTTGGACCCGCCCAGCAGCACCACGGACCCCAGCCACTCTCGGGGGCAGACGTCAGAATCCGTTC CTGAGCAGCTCCTGTGCCCTGGGGGCAGTCACAGAGCCCCCCAACACCCCCGTGCTCTGCACCAGCCTC TCCCTCCACACCCGAAGCAGGCGTCCATCTGTGTCCTCCTGGCAGCCCCTCAAACACACACCACCCCAT GTCACACGGGTATCCAGAGCAAGGCTGGATCTGGGCTAGGTGACCCCTGGGGCCTCAGACCTCTGAGTG GGCCCCAGAGCCCAGCTGAGGAAGCCACACAGCCTCCAGGACGTGGCACGGTTCCCCTCCACTTGGCTG CAAGTCGCCTGCCATGGGGCGAGGAGGCCTGCACCCCAGTATAAGGGCCTCCCCAGCTGAGTAAGAAGC TGCTTCCCCTCCTCTCATAGGCCAAGCCTATTGTGTGAAACCATCTCATGGTCTTGGTGACGTAGACCA TTTTTGAAACCGTCTCATGGTCTTGGTGACGTAGACCGTTTGCTTCTTTAACTCCAGCCGCGGAATGAC ATTAGTGGAACCGGGCTAGGGAACTGCTGGAAGTTCAGGATGCCACCACCTTGAACACCTAGGCCAGGG ATCCCCACCATGTCCCGGGTTTCTTTCTTCGAGAGTATAGAACCGTTCATTCTTGCTTTGTGTCCCATT CCATCTCTTGAAAAAATGTAGTCTTTGAATGTGTGAAAATCTAGGGACATTCAATCTAGTCTTTTAAAT TATTTTTCCATATTTATATTTTTAAATAAATGCATATATTGAGTCTTAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_019892.6
Synonyms	CORS1; CPD4; JBTS1; MORMS; pharbin; PPI5PIV
Summary	The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,5-bisphosphate on the cytoplasmic Golgi membrane and thereby regulate Golgi-vesicular trafficking. Mutations in this gene cause Joubert syndrome; a clinically and genetically heterogenous group of disorders characterized by midbrain-hindbrain malformation and various associated ciliopathies that include retinal dystrophy, nephronophthisis, liver fibrosis and polydactyly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
Locus ID	56623
MW	40.3

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