ASAH1 (NM_004315) Human 3' UTR Clone

Specifications

Product Data
Product Name	ASAH1 (NM_004315) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AC; ACDase; ASAH; PHP; PHP32; SMAPME
ACCN	NM_004315
Insert Size	1572 bp
Sequence Data	Insert Sequence (showhide) >SC212561 3’UTR clone of NM_004315 The sequence shown below is from the reference sequence of NM_004315. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GACTGCCCTGACCCTTGTATAGGTTGGTGAGCACACGTCTGGCCTACAGAATGCGGCCTCTGAGACATG AAGACACCATCTCCATGTGACCGAACACTGCAGCTGTCTGACCTTCCAAAGACTAAGACTCGCGGCAGG TTCTCTTTGAGTCAATAGCTTGTCTTCGTCCATCTGTTGACAAATGACAGATCTTTTTTTTTTCCCCCT ATCAGTTGATTTTTCTTATTTACAGATAACTTCTTTAGGGGAAGTAAAACAGTCATCTAGAATTCACTG AGTTTTGTTTCACTTTGACATTTGGGGATCTGGTGGGCAGTCGAACCATGGTGAACTCCACCTCCGTGG AATAAATGGAGATTCAGCGTGGGTGTTGAATCCAGCACGTCTGTGTGAGTAACGGGACAGTAAACACTC CACATTCTTCAGTTTTTCACTTCTACCTACATATTTGTATGTTTTTCTGTATAACAGCCTTTTCCTTCT GGTTCTAACTGCTGTTAAAATTAATATATCATTATCTTTGCTGTTATTGACAGCGATATAATTTTATTA CATATGATTAGAGGGATGAGACAGACATTCACCTGTATATTTCTTTTAATGGGCACAAAATGGGCCCTT GCCTCTAAATAGCACTTTTTGGGGTTCAAGAAGTAATCAGTATGCAAAGCAATCTTTTATACAATAATT GAAGTGTTCCCTTTTTCATAATTACTCTACTTCCCAGTAACCCTAAGGAAGTTGCTAACTTAAAAAACT GCATCCCACGTTCTGTTAATTTAGTAAATAAACAAGTCAAAGACTTGTGGAAAATAGGAAGTGAACCCA TATTTTAAATTCTCATAAGTAGCATTCATGTAATAAACAGGTTTTTAGTTTGTTCTTCAGATTGATAGG GAGTTTTAAAGAAATTTTAGTAGTTACTAAAATTATGTTACTGTATTTTTCAGAAATCAAACTGCTTAT GAAAAGTACTAATAGAACTTGTTAACCTTTCTAACCTTCACGATTAACTGTGAAATGTACGTCATTTGT GCAAGACCGTTTGTCCACTTCATTTTGTATAATCACAGTTGTGTTCCTGACACTCAATAAACAGTCACT GGAAAGAGTGCCAGTCAGCAGTCATGCACGCTGATTGGGTGTGTACATCTGTGTTGGTTTGGAGGAGGG GGGTTATTATCAAGAAATACAAGCTGAACATCGTATCTGAATTAAATAACAAGGGTTATGTAAGTGGGT TATTAAATATGACTAAACGGTCACAATCTTACTCTTACATGACTGATACCACCTCTTAACCAGATACTA TCAACCCAATTTGCAGGTGTTTAAAGGCAGTTTTTCCCCCAGATAGGTGGTGCTTCCACAAAACTTTAG TGATTCCAAGATTACTTTAGTGAAACGAGGAATTATAAGAGGATTTACATTAAAATAGGATTTAATTAA TGAAAAAAAAACTTTACTCAGATTTTCTACCTCTTACATAAATGAAGTCAGGTCAACTTGATGTATTTT TTTGTTAATGTAATAACCTTTGATATGCCTGATAGTAAAGAGGTGAGATGCTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004315.6
Synonyms	AC; ACDase; ASAH; PHP; PHP32; SMAPME
Summary	This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy. [provided by RefSeq, Oct 2015]
Locus ID	427
MW	60.4

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